Research Topics
Species | M A MillerSummaryAffiliation: Purdue University Country: USA Publications
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Detail Information
Publications
Extraskeletal osteosarcoma associated with retained surgical sponge in a dogMargaret A Miller
Department of Veterinary Pathobiology, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907, USA
J Vet Diagn Invest 18:224-8. 2006..Three months after surgical excision, the dog was euthanized because of local recurrence of the mass along with lameness and decreased appetite...
Synovial hemangioma in the stifle joint of a dogM A Miller
Animal Disease Diagnostic Laboratory, Department of Veterinary Pathology, Purdue University, 406 S University St, West Lafayette, IN 47907, USA
Vet Pathol 44:240-3. 2007..Synovial hemangioma is a rare benign vascular proliferation in people, most commonly in the knee, and should be included in the differential diagnosis for canine synovial tumors...
Interstitial cell tumor and Sertoli cell tumor in the testis of a catM A Miller
Department of Veterinary Pathology, Purdue University, West Lafayette, IN 47907, USA
Vet Pathol 44:394-7. 2007..Neither tumor had metastasized. The right testis was never found and was presumed to have been removed during the reported castration procedure...
Mandibular ossifying fibroma in a dogM A Miller
Animal Disease Diagnostic Laboratory, Purdue University, 406 S University Street, West Lafayette, IN 47907, USA
Vet Pathol 45:203-6. 2008..Although benign, en bloc excision may be necessary for surgical cure...
Correlation of pituitary histomorphometry with adrenocorticotrophic hormone response to domperidone administration in the diagnosis of equine pituitary pars intermedia dysfunctionM A Miller
Animal Disease Diagnostic Laboratory, Department of Comparative Pathobiology, Purdue University, West Lafayette, IN 47907, USA
Vet Pathol 45:26-38. 2008..3 years, 128.0 pg/ml, 0.87 cm(2); grade 5 (adenoma), n = 4, 24.9 years, 720.5 pg/ml, 2.1 cm(2). Results suggest that horses with pituitary histologic grade > or =3 respond to domperidone with increased plasma ACTH concentration...
Immunohistochemical evaluation of GATA-4 in canine testicular tumorsJ A Ramos-Vara
Animal Disease Diagnostic Laboratory, Purdue University, 406 South University, West Lafayette, IN 47907, USA
Vet Pathol 46:893-6. 2009..GCTs were negative for this marker. Sex cord-stromal cells of MGSCT were also positive. These results indicate that GATA-4 is mainly expressed in sex cord-stromal tumors and not in germ cell tumors of the canine testis...
Immunohistochemical detection of CD34, E-cadherin, claudin-1, glucose transporter 1, laminin, and protein gene product 9.5 in 28 canine and 8 feline meningiomasJ A Ramos-Vara
Animal Disease Diagnostic Laboratory, Purdue University, 406 South University, West Lafayette, IN 47907, USA
Vet Pathol 47:725-37. 2010..Further studies with CD34, E-cadherin, and claudin-1 in canine and feline tumors that may mimic meningiomas are needed to determine the adequacy of this approach...
Immunohistochemical detection of multiple myeloma 1/interferon regulatory factor 4 (MUM1/IRF-4) in canine plasmacytoma: comparison with CD79a and CD20J A Ramos-Vara
Animal Disease Diagnostic Laboratory, Purdue University, 406 South University, West Lafayette, IN 47907, USA
Vet Pathol 44:875-84. 2007....
Immunohistochemical expression of E-cadherin does not distinguish canine cutaneous histiocytoma from other canine round cell tumorsJ A Ramos-Vara
Department of Comparative Pathobiology, Purdue University, West Lafayette, IN 47907, USA
Vet Pathol 48:758-63. 2011....
Effects of prolonged formalin fixation on diagnostic immunohistochemistry in domestic animalsJoshua D Webster
Animal Disease Diagnostic Laboratory, Department of Comparative Pathobiology, School of Veterinary Medicine, Purdue University, 406 S University, West Lafayette, IN 47907, USA
J Histochem Cytochem 57:753-61. 2009..These results suggest that prolonged formalin fixation has minimal effects on antigen detection for most commonly used antibodies. These results further validate the use of IHC in diagnostic pathology...
Comparison of CD34, CD31, and factor VIII-related antigen immunohistochemical expression in feline vascular neoplasms and CD34 expression in feline nonvascular neoplasmsR N Jennings
Animal Disease Diagnostic Laboratory and Department of Comparative Pathobiology, Purdue University, 406 South University, West Lafayette, IN 47907, USA
Vet Pathol 49:532-7. 2012..Given the broad expression of CD34 in mesenchymal neoplasms, this marker has limited diagnostic relevance for vascular neoplasms of cats...
Evaluation of the effects of transendoscopic diode laser palatoplasty on clinical, histologic, magnetic resonance imaging, and biomechanical findings in horsesKira C Alkabes
Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907, USA
Am J Vet Res 71:575-82. 2010..To determine the effects of diode laser palatoplasty on the soft palate in horses...
Glomerulocystic kidney disease in a Belgian Malinois dog: an ultrastructural, immunohistochemical, and lectin-binding studyJose A Ramos-Vara
Animal Disease Diagnostic Laboratory, Purdue University, West Lafayette, Indiana, USA
Ultrastruct Pathol 28:33-42. 2004..The presence of parietal podocytes in all cysts suggests that abnormal differentiation may play an important role in the pathogenesis of this type of polycystic kidney disease...
Nocardia tenerifensis genome identification in a cutaneous granuloma of a catJose A Ramos-Vara
Animal Disease Diagnostic Laboratory and Department of Comparative Pathobiology, Purdue University, West Lafayette, IN 47907, USA
J Vet Diagn Invest 19:577-80. 2007..and had the highest sequence homology of 98.2% with Nocardia tenerifensis among Nocardia spp. To the authors' knowledge, this is the first report of detection of N. tenerifensis genome associated with cutaneous nocardiosis in an animal...
Toxoplasmosis in a woodchuck (Marmota monax) and two American red squirrels (Tamiasciurus hudsonicus)Dinesh S Bangari
Department of Comparative Pathobiology, School of Veterinary Medicine, Animal Disease Diagnostic Laboratory, Purdue University, West Lafayette, IN 47907, USA
J Vet Diagn Invest 19:705-9. 2007..Because rodents are common near urban settlements, this finding underscores their role as important intermediate hosts for T. gondii...
Fatal ricin toxicosis in a puppy confirmed by liquid chromatography/mass spectrometry when using ricinine as a markerPamela Mouser
Animal Disease Diagnostic Laboratory, Purdue University, West Lafayette, IN, USA
J Vet Diagn Invest 19:216-20. 2007....
Comparison of two polymer-based immunohistochemical detection systems: ENVISION+ and ImmPRESSJose A Ramos-Vara
Purdue University, Animal Disease Diagnostic Laboratory, School of Veterinary Medicine, 406 South University, West Lafayette, IN 47905, USA
J Microsc 224:135-9. 2006..The cost of ImmPRESS was 25% lower than for ENVISION+trade mark. Based on these results, ImmPRESS is a good polymer-based detection system for routine immunohistochemistry...
Evaluation of minimally invasive excisional brain biopsy and intracranial brachytherapy catheter placement in dogsRebecca A Packer
Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907, USA
Am J Vet Res 72:109-21. 2011..To evaluate a technique for minimally invasive excisional brain biopsy and intracranial brachytherapy catheter placement in dogs...
Immunohistochemical detection of protein gene product 9.5 (PGP 9.5) in canine epitheliotropic T-cell lymphoma (mycosis fungoides)J A Ramos-Vara
Animal Disease Diagnostic Laboratory, Purdue University, West Lafayette, IN 47907, USA
Vet Pathol 44:74-9. 2007..This unexpected staining of lymphocytes in mycosis fungoides with an antibody to PGP 9.5 demonstrates its presence in nonneuroendocrine tumors and precludes its use as the sole diagnostic marker in discrete cell tumors in the skin...
Metritis, valvular endocarditis, and septicemia by Actinobacillus equuli in a gilt in the United StatesJ A Ramos-Vara
Animal Disease Diagnostic Laboratory, Purdue University, 406 South University, West Lafayette, IN 47907, USA
Vet Pathol 45:495-9. 2008..A. equuli in pigs in the United States has been reported only twice and not, to our knowledge, in the last 30 years. This is the first time that molecular techniques have been used to characterize this organism in FFPE porcine tissues...
Immunohistochemical identification of canine melanocytic neoplasms with antibodies to melanocytic antigen PNL2 and tyrosinase: comparison with Melan AJ A Ramos-Vara
Department of Comparative Pathbiology, Purdue University, West Lafayette, IN 47907, USA
Vet Pathol 48:443-50. 2011..Results indicate that PNL2 is an excellent marker in the identification of canine melanomas and that the sensitivity is close to 100% when used in conjunction with Melan A and tyrosinase...
Diagnostic exercise. Cerebral mass in a puppy with respiratory distress and progressive neurologic signsL T Reed
Purdue University, Animal Disease Diagnostic Laboratory, 406 S University St, West Lafayette, IN 47907 Email
Vet Pathol 47:1116-9. 2010..Concurrent infections included canine distemper, canine adenoviral bronchiolitis, and oral candidiasis. Canine distemper virus probably caused immunosuppression and increased susceptibility to secondary infections...
Prevalence and classification of spontaneous mammary intraepithelial lesions in dogs without clinical mammary diseaseP Mouser
Department of Comparative Pathobiology, Purdue University, West Lafayette, IN 47907, USA
Vet Pathol 47:275-84. 2010....
Effects of prolonged formalin fixation on the immunohistochemical detection of infectious agents in formalin-fixed, paraffin-embedded tissuesJ D Webster
Animal Disease Diagnostic Laboratory, School of Veterinary Medicine, Purdue University, 406 South University, West Lafayette, IN 47907, USA
Vet Pathol 47:529-35. 2010..However, the effects of prolonged fixation depend on the targeted antigen and the selected antibody. The results of this study further validate the utility and reliability of immunohistochemistry in diagnostic pathology...
Encephalitozoon cuniculi-associated placentitis and perinatal death in an alpaca (Lama pacos)J D Webster
Animal Disease Diagnostic Laboratory, Purdue University, 406 S University, West Lafayette, IN 47907, USA
Vet Pathol 45:255-8. 2008..No organisms were detected in tissues other than the placenta. This is the first reported case of E. cuniculi infection in an alpaca...
Isolation and characterization of Sarcocystis from brain tissue of a free-living southern sea otter (Enhydra lutris nereis) with fatal meningoencephalitisM A Miller
Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis 95616-8739, USA
Parasitol Res 87:252-7. 2001..This isolate (SO SN1), was indistinguishable from S. neurona, based on parasite morphology, antigenic reactivity and molecular characterization...
Radiofrequency-induced thermal inactivation of Toxoplasma gondii oocysts in waterK E Wainwright
Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, CA, USA
Zoonoses Public Health 57:74-81. 2010..The impact of factors such as water heating time, cooling time and the volume of water treated must be considered when evaluating the efficacy of RF power for oocyst inactivation...
Usefulness of thyroid transcription factor-1 immunohistochemical staining in the differential diagnosis of primary pulmonary tumors of dogsJ A Ramos-Vara
Animal Disease Diagnostic Laboratory, Purdue University, 406 South University, West Lafayette, IN 47907, USA
Vet Pathol 42:315-20. 2005..On the basis of our limited studies and the human literature, it appears that MoAb 8G7G3/1 to TTF-1 is a highly specific (with the exception of thyroid tumors) and moderately sensitive marker for canine pulmonary epithelial tumors...
Testicular interstitial cell tumor and gynecomastia in a rabbitK A Maratea
Animal Disease Diagnostic Laboratory, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907, USA
Vet Pathol 44:513-7. 2007..This is the first report of concurrent interstitial cell tumor and gynecomastia in a rabbit and also the first description of gynecomastia in this species...
Cutaneous and systemic poxviral disease in red (Tamiasciurus hudsonicus) and gray (Sciurus carolinensis) squirrelsD S Bangari
Department of Comparative Pathobiology, College of Veterinary Medicine, Purdue University, 406 S University Street, West Lafayette, IN 47907, USA
Vet Pathol 46:667-72. 2009..To the authors' knowledge, this is the first report of cutaneous and systemic poxviral disease in American red squirrels with molecular characterization of the squirrel fibroma virus...
New genotypes and factors associated with Cryptosporidium detection in mussels (Mytilus spp.) along the California coastW A Miller
School of Veterinary Medicine, University of California, Davis, CA 95616, USA
Int J Parasitol 35:1103-13. 2005....
Evaluation of immune responses in horses immunized using a killed Sarcocystis neurona vaccineAntoinette E Marsh
Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
Vet Ther 5:34-42. 2004..neurona encephalitis has been established that allows for reisolation of the pathogen after challenge...
Effects of delayed or prolonged fixation on immunohistochemical detection of bovine viral diarrhea virus type I in skin of two persistently infected calvesMargaret A Miller
Department of Veterinary Pathobiology, Animal Disease Diagnostic Laboratory, Purdue University, West Lafayette, IN 47907, USA
J Vet Diagn Invest 17:461-3. 2005..Samples can be held in formalin at least 36 days, without loss of reactivity. A 1-day delay in fixation caused no loss of reactivity, provided the specimen was refrigerated and protected from desiccation...
Phase I clinical trial of the use of zinc phthalocyanine tetrasulfonate as a photosensitizer for photodynamic therapy in dogsAntonella Borgatti Jeffreys
Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907, USA
Am J Vet Res 68:399-404. 2007....
Spontaneous mammary intraepithelial lesions in dogs--a model of breast cancerElisabetta Antuofermo
Department of Comparative Pathobiology, Purdue University, West Lafayette, IN 47907, USA
Cancer Epidemiol Biomarkers Prev 16:2247-56. 2007....
Patterns of mortality in southern sea otters (Enhydra lutris nereis) from 1998-2001C Kreuder
Wildlife Health Center, School of Veterinary Medicine, University of California, Davis, California 95616, USA
J Wildl Dis 39:495-509. 2003..1% of otters examined. This pattern of mortality, observed predominantly in juvenile and prime-aged adult southern sea otters, has negative implications for the overall health and recovery of this population...
Ultrastructural changes and olfactory deficits during 3-methylindole-induced olfactory mucosal necrosis and repair in miceMargaret A Miller
Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, UMC Veterinary Medfical Diagnostic Laboratory, PO Box 6023, Columbia, MO 65205, USA
Ultrastruct Pathol 27:13-21. 2003..Though olfactory neurons were initially spared, their absence in the regenerated epithelium explains lingering olfactory deficits in murine 3MI toxicosis...
Immunohistochemical analysis of matrix metalloproteinase-1, -3, and -13 in naturally occurring cartilaginous tumors of dogsKeiichi Kuroki
Comparative Orthopaedic Laboratory, College of Veterinary Medicine, University of Missouri, Columbia 65211, USA
Am J Vet Res 63:1285-91. 2002....
Heart failure caused by toxoplasmosis in a fennec fox (Fennecus zerda)Jack J Kottwitz
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, Missouri 65201, USA
J Am Anim Hosp Assoc 40:501-7. 2004..Toxoplasma-induced myocarditis should be included in the differential diagnosis of heart failure and retinochoroiditis in the fennec fox...
Agreement in histologic assessments of the pituitary pars intermedia in aged horsesDianne McFarlane
Department of Biomedical Sciences, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, PE C1A 4P3, Canada
Am J Vet Res 66:2055-9. 2005..Caution should be used when interpreting diagnostic test results in horses in which early PPID is suspected...
Uterine neoplasia in 13 catsMargaret A Miller
Veterinary Medical Diagnostic Laboratory and Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, PO Box 6023, Columbia, MO 65205, USA
J Vet Diagn Invest 15:515-22. 2003..Metastasis was not detected in any mesenchymal tumor; however, these cats were either euthanized on discovery of the tumor or the tumor was first detected at necropsy...
Hypoglycemia and tumor lysis syndrome associated with peritoneal mesothelioma in a horseAlison M Lacarrubba
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia 65211, USA
J Vet Intern Med 20:1018-22. 2006
