Research Topics
Species | PETER HOLLENBECKSummaryAffiliation: Purdue University Country: USA Publications
Research Grants
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Detail Information
Publications
Mitochondrial movement and positioning in axons: the role of growth factor signalingSonita R Chada
Department of Biological Sciences, Purdue University, West Lafayette, IN 47907-1392, USA
J Exp Biol 206:1985-92. 2003..We propose that mitochondrial transport and/or docking are regulated in part via NGF/TrkA/PI 3-kinase signaling...- Comparing the properties of neuronal culture systems: a shopping guide for the cell biologistPeter J Hollenbeck
Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907, USA
Methods Cell Biol 71:1-16. 2003.... - Nerve growth factor signaling regulates motility and docking of axonal mitochondriaSonita R Chada
Department of Biological Sciences, Purdue University, West Lafayette, IN 47907-1392 USA
Curr Biol 14:1272-6. 2004.... 
Mitochondrial membrane potential in axons increases with local nerve growth factor or semaphorin signalingJessica Verburg
Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47906, USA
J Neurosci 28:8306-15. 2008..Thus, two guidance molecules that exert different effects on growth cone motility both elicit local, receptor-mediated increases in membrane potential...- Cytoskeleton: Microtubules get the signalP Hollenbeck
Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907, USA
Curr Biol 11:R820-3. 2001..Recent work in fibroblasts shows that microtubules are also subject to regulation by the Rho pathway, and that the signals acting on actin and microtubules can be teased apart... - The axonal transport of mitochondriaPeter J Hollenbeck
Department of Biological Sciences, Purdue University, 915 West State Street, West Lafayette, IN 47907, USA
J Cell Sci 118:5411-9. 2005.... - Mitochondria and neurotransmission: evacuating the synapsePeter J Hollenbeck
Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907, USA
Neuron 47:331-3. 2005..Now, evidence from the nervous system of Drosophila identifies the specific subcellular events that are most dependent upon nearby mitochondria... - Organization and translation of mRNA in sympathetic axonsSun Kyung Lee
Department of Biological Sciences, Purdue University, West Lafayette, IN 47906, USA
J Cell Sci 116:4467-78. 2003.... - Response of mitochondrial traffic to axon determination and differential branch growthGordon Ruthel
Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907 2504, USA
J Neurosci 23:8618-24. 2003.... - Evidence that myosin activity opposes microtubule-based axonal transport of mitochondriaDivya Pathak
Department of Biological Sciences and Purdue University Integrative Neuroscience Program, West Lafayette, IN 47907, USA
J Neurosci 30:8984-92. 2010..These data indicate that myosin V and VI play related but distinct roles in regulating MT-based mitochondrial movement: they oppose, rather than complement, protracted MT-based movements and perhaps facilitate organelle docking... - Mitochondrial biogenesis in the axons of vertebrate peripheral neuronsMandana Amiri
Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47906, USA
Dev Neurobiol 68:1348-61. 2008..These data indicate that mitochondria can replicate their DNA, divide, and fuse locally within the axon; thus, the biogenesis of mitochondria is not limited to the cell body... - Expression of transgenes in primary neurons from chick peripheral and central nervous systems by retroviral infection of early embryosPeter J Hollenbeck
Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907, USA
Methods Cell Biol 71:369-86. 2003..In this manner, the majority of the sympathetic and dorsal root ganglion neurons can be induced to express the trangene. A similar result, at lower efficiencies, is obtained for central nervous system neurons... - Defects in mitochondrial axonal transport and membrane potential without increased reactive oxygen species production in a Drosophila model of Friedreich ataxiaYujiro Shidara
Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907, USA
J Neurosci 30:11369-78. 2010..We propose that pathology in the frataxin-deficient nervous system involves decreased MMP and ATP production followed by failures of mitochondrial transport and NMJ function... - Transfection of primary central and peripheral nervous system neurons by electroporationCecilia Y Martinez
Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47906, USA
Methods Cell Biol 71:339-51. 2003..We emphasize the rationale for each element in our method and provide information useful for optimizing the procedure for other neurons...
Research Grants
- Control of Neural Organelle TransportPETER HOLLENBECK; Fiscal Year: 2007..The information provided by these experiments in chick neurons may aid in understanding the molecular and cellular basis of human nerve injury and neurodegenerative diseases. ..
- CONTROL OF NEURONAL ORGANELLE TRANSPORTPETER HOLLENBECK; Fiscal Year: 2003..abstract_text> ..
- CONTROL OF NEURONAL ORGANELLE TRANSPORTPeter J Hollenbeck; Fiscal Year: 2010..Our hope is that this knowledge will aid in designing new treatments for these disorders. ..