Research Topics
| Zhilan FengSummaryAffiliation: Purdue University Country: USA Publications
| Collaborators
|
Detail Information
Publications
Pandemic H1N1 influenza: predicting the course of a pandemic and assessing the efficacy of the planned vaccination programme in the United StatesS Towers
Department of Statistics, Purdue University, West Lafayette, Indiana, USA
Euro Surveill 14:19358. 2009....
A mathematical model for coupling within-host and between-host dynamics in an environmentally-driven infectious diseaseZhilan Feng
Department of Mathematics, Purdue University, West Lafayette, Indiana, USA
Math Biosci 241:49-55. 2013..We show that these reproduction numbers determine the stability of the infection-free and the endemic equilibrium points. Our model may present a so-called backward bifurcation...
Modeling the effects of vaccination and treatment on pandemic influenzaZhilan Feng
Department of Mathematics, Purdue University, West Lafayette, Indiana 47906, USA
AAPS J 13:427-37. 2011..Particularly, the models can help identify potential adverse effects of vaccination and drug treatment in the case of pandemic influenza...
Coexistence in a metapopulation model with explicit local dynamicsZhilan Feng
Department of Mathematics, Purdue University, West Lafayette, IN 47907
Math Biosci Eng 1:131-45. 2004..Our results show that the coupled system leads to more complex outcomes than simple patch models which do not include explicit local dynamics. We also discuss implications of the model for ecological systems in fragmented landscapes...
The influence of infectious diseases on population geneticsZhilan Feng
Department of Mathematics, Purdue University, West Lafayette, IN 47907
Math Biosci Eng 3:467-83. 2006..We start from the published results of an earlier model and proceed to remove some model restrictions in order to better understand the impact on the natural hosts' genetics in an environment where malaria is endemic...
Schistosomiasis models with density dependence and age of infection in snail dynamicsZhilan Feng
Department of Mathematics, Purdue University, West Lafayette, IN 47907 1395, USA
Math Biosci 177:271-86. 2002..Evaluations of cost-effectiveness are also discussed by analyzing the sensitivity of the mean number of parasites per person to changes of other parameters...
Final and peak epidemic sizes for SEIR models with quarantine and isolationZhilan Feng
Department of Mathematics, Purdue University, West Lafayette, IN 47907, USA
Math Biosci Eng 4:675-86. 2007....
Epidemiological models with non-exponentially distributed disease stages and applications to disease controlZhilan Feng
Department of Mathematics, Purdue University, West Lafayette, IN 47907, USA
Bull Math Biol 69:1511-36. 2007..Numerical simulations suggest that models that assume exponential and non-exponential stage distribution assumptions can produce inconsistent predictions...
The influence of drug treatment on the maintenance of schistosome genetic diversityZ Feng
Department of Mathematics, Purdue University, West Lafayette, IN 47907, USA
J Math Biol 43:52-68. 2001....
Evolution of host resistance to parasite infection in the snail-schistosome-human systemYiding Yang
Department of Mathematics, Purdue University, West Lafayette, IN 47907, USA
J Math Biol 65:201-36. 2012..Results from this work demonstrate that the evolutionary trajectories of host-parasite interactions can be varied, and at times, counter-intuitive, based on parasite virulence, host resistance, and drug treatment...
Interactions among virulence, coinfection and drug resistance in a complex life-cycle parasiteDashun Xu
Department of Mathematics, Southern Illinois University, Carbondale, IL 62901, USA
J Theor Biol 304:197-210. 2012..This calls for more empirical studies on the parasite...
On the role of schistosome mating structure in the maintenance of drug-resistant strainsDashun Xu
Department of Mathematics, Purdue University, West Lafayette, IN 47907, USA
Bull Math Biol 68:209-29. 2006....
Timely identification of optimal control strategies for emerging infectious diseasesZhilan Feng
Department of Mathematics, Purdue University, West Lafayette, IN 47907, USA
J Theor Biol 259:165-71. 2009..Health authorities must rely on quarantine, isolation, and other non-pharmaceutical interventions to contain outbreaks of newly emerging human diseases...
Dynamics of a plant-herbivore-predator system with plant-toxicityZhilan Feng
Department of Mathematics, Purdue University, West Lafayette, IN 47907, USA
Math Biosci 229:190-204. 2011..This model can be applied to a boreal ecosystem trophic chain to examine the possible cascading effects of predator-control actions when plant species differ in their levels of toxic defense...
A schistosomiasis model with an age-structure in human hosts and its application to treatment strategiesPei Zhang
Mathematics Department, Purdue University, West Lafayette, IN 47907, USA
Math Biosci 205:83-107. 2007..The effects of various drug treatment programs on disease control are compared in terms of both R and the mean parasite load within the human hosts...
Evolutionary implications for interactions between multiple strains of host and parasitePei Zhang
Department of Mathematics, Purdue University, West Lafayette, IN 47907, USA
J Theor Biol 248:225-40. 2007..We identify conditions that determine the evolution of parasite specialism or generalism based on the life-history strategies employed by hosts, and investigate how host strains may influence parasite persistence...
Coupling ecology and evolution: malaria and the S-gene across time scalesZhilan Feng
Department of Mathematics, Purdue University, West Lafayette, IN 47907 1395, USA
Math Biosci 189:1-19. 2004..We analyze the slow time scale dynamics to investigate the impact of malaria on the evolution of resistance...
Merging spatial and temporal structure within a metapopulation modelYssa D DeWoody
Department of Forestry and Natural Resources, Purdue University, West Lafayette, Indiana 47907 2061, USA
Am Nat 166:42-55. 2005..This model allows for an expansion of the classic definition of a patch and should prove useful when considering species inhabiting complex dynamic landscapes, for example, agricultural landscapes...
The impact of school closures on pandemic influenza: Assessing potential repercussions using a seasonal SIR modelSherry Towers
Department of Mathematics, Purdue University, West Lafayette, IN 47907, United States
Math Biosci Eng 9:413-30. 2012..Our studies thus suggest that when heterogeneity in transmission is a significant factor, decisions of public health policy will be particularly important as to how control measures such as school closures should be implemented...
On the role of schistosome mating structure in the maintenance of drug resistant strainsDashun Xu
Department of Mathematics, Purdue University, West Lafayette, IN 47907, USA
Bull Math Biol 67:1207-26. 2005....
A spatially structured metapopulation model with patch dynamicsDashun Xu
Department of Mathematics, Purdue University, West Lafayette, IN 47907, USA
J Theor Biol 239:469-81. 2006..We also derive a stochastic differential equations (SDE) model of the Itô type based on our deterministic model. Our simulations reveal good agreement between the deterministic model and the SDE model...
Plant-herbivore interactions mediated by plant toxicityZhilan Feng
Department of Mathematics, Purdue University, West Lafayette, IN 47907, United States
Theor Popul Biol 73:449-59. 2008....
Troublesome toxins: time to re-think plant-herbivore interactions in vertebrate ecologyRobert K Swihart
Department of Forestry and Natural Resources, Purdue University, West Lafayette, IN 47907, USA
BMC Ecol 9:5. 2009..Future ecological studies will need to address explicitly the importance of plant toxins in shaping plant and herbivore communities...
Cats protecting birds revisitedMeng Fan
School of Mathematics and Statistics and Key Laboratory for Vegetation Ecology of the Education Ministry, Northeast Normal University, 5268 Renmin Street, Changchun, Jilin 130024, People s Republic of China
Bull Math Biol 67:1081-106. 2005..The presence of a superpredator may have a beneficial effect in such systems...
A schistosomiasis model with mating structure and time delayCarlos Castillo-Chavez
Department of Mathematics and Statistics, Arizona State University, Tempe, AZ 85287, USA
Math Biosci 211:333-41. 2008..However, quantitatively the time delays make it more likely for drug-resistant strains to invade in a parasite population...
Emergence of drug resistance: implications for antiviral control of pandemic influenzaMurray E Alexander
Institute for Biodiagnostics, National Research Council Canada, Winnipeg, Manitoba, Canada
Proc Biol Sci 274:1675-84. 2007..4 emerge. While an antiviral strategy is crucial for containing a pandemic, its effectiveness depends critically on timely and strategic use of drugs...
