Henry C Chang


Affiliation: Purdue University
Country: USA


  1. Bai T, Seebald J, Kim K, Ding H, Szeto D, Chang H. Disruption of zebrafish cyclin G-associated kinase (GAK) function impairs the expression of Notch-dependent genes during neurogenesis and causes defects in neuronal development. BMC Dev Biol. 2010;10:7 pubmed publisher
    ..In addition, our analysis suggests that zebrafish GAK has at least two functions during the development of neural tissues: an early Notch-dependent role in neuronal patterning and a late role in maintaining the survival of neural cells. ..
  2. Kandachar V, Bai T, Chang H. The clathrin-binding motif and the J-domain of Drosophila Auxilin are essential for facilitating Notch ligand endocytosis. BMC Dev Biol. 2008;8:50 pubmed publisher
    ..Together, our observations argue that ligand endocytosis is critical for Notch signaling and auxilin participates in Notch signaling by facilitating ligand internalization. ..