Kolapo M Ajuwon

Summary

Affiliation: Purdue University
Country: USA

Publications

  1. ncbi request reprint Chronic immune stimulation in adipose tissue and its consequences for health and performance in the pig
    Kolapo M Ajuwon
    Department of Animal Sciences, Purdue University, West Lafayette, IN 47907, USA Electronic address
    Vet Immunol Immunopathol 159:166-70. 2014
  2. pmc Dietary fat content and fiber type modulate hind gut microbial community and metabolic markers in the pig
    Hui Yan
    Department of Animal Sciences, Purdue University, West Lafayette, Indiana, United States of America
    PLoS ONE 8:e59581. 2013
  3. pmc Biglycan deletion alters adiponectin expression in murine adipose tissue and 3T3-L1 adipocytes
    Meliza G Ward
    Department of Animal Sciences, Purdue University, West Lafayette, Indiana, United States of America
    PLoS ONE 7:e50554. 2012
  4. pmc Metabolic markers in Ossabaw pigs fed high fat diets enriched in regular or low α-linolenic acid soy oil
    Ramesh B Potu
    Department of Animal Sciences, Purdue University, West Lafayette, IN 47907, USA
    Nutr Metab (Lond) 10:27. 2013
  5. pmc Adipose tissue biglycan as a potential anti-inflammatory target of sodium salicylate in mice fed a high fat diet
    Venkata J Adapala
    Department of Animal Sciences, Purdue University, West Lafayette, IN, 47907 2054, USA
    J Inflamm (Lond) 9:15. 2012
  6. pmc Novel anti-inflammatory role of SLPI in adipose tissue and its regulation by high fat diet
    Venkata J Adapala
    Department of Animal Sciences, Purdue University, West Lafayette, Indiana, 47907, USA
    J Inflamm (Lond) 8:5. 2011
  7. pmc Stimulation with Peptidoglycan induces interleukin 6 and TLR2 expression and a concomitant downregulation of expression of adiponectin receptors 1 and 2 in 3T3-L1 adipocytes
    Kolapo M Ajuwon
    Department of Animal Sciences, Purdue University, West Lafayette, IN 47907, USA
    J Inflamm (Lond) 6:8. 2009
  8. ncbi request reprint Adiponectin inhibits LPS-induced NF-kappaB activation and IL-6 production and increases PPARgamma2 expression in adipocytes
    Kolapo M Ajuwon
    Department of Animal Sciences, Comparative Medicine Center, Purdue Univ, 3 230 Lilly Hall of Life Sciences, 915 W State St, West Lafayette, IN 47907 2054, USA
    Am J Physiol Regul Integr Comp Physiol 288:R1220-5. 2005
  9. ncbi request reprint Chronic leptin administration increases serum NEFA in the pig and differentially regulates PPAR expression in adipose tissue
    Kolapo M Ajuwon
    Department of Animal Sciences, Purdue University, West Lafayette, IN, USA
    J Nutr Biochem 14:576-83. 2003
  10. ncbi request reprint Adiponectin differentially regulates cytokines in porcine macrophages
    Meghan C Wulster-Radcliffe
    Department of Animal Sciences, Comparative Medicine Program, Purdue University, West Lafayette, IN, USA
    Biochem Biophys Res Commun 316:924-9. 2004

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Chronic immune stimulation in adipose tissue and its consequences for health and performance in the pig
    Kolapo M Ajuwon
    Department of Animal Sciences, Purdue University, West Lafayette, IN 47907, USA Electronic address
    Vet Immunol Immunopathol 159:166-70. 2014
    ..Because chronic inflammation is linked to impairment of animal health and optimal growth efficiency, strategies are needed to minimize exposure to factors that may activate immune response in pigs. ..
  2. pmc Dietary fat content and fiber type modulate hind gut microbial community and metabolic markers in the pig
    Hui Yan
    Department of Animal Sciences, Purdue University, West Lafayette, Indiana, United States of America
    PLoS ONE 8:e59581. 2013
    ..This study suggests a strong interplay between dietary fat level and fiber type in determining susceptibility to obesity...
  3. pmc Biglycan deletion alters adiponectin expression in murine adipose tissue and 3T3-L1 adipocytes
    Meliza G Ward
    Department of Animal Sciences, Purdue University, West Lafayette, Indiana, United States of America
    PLoS ONE 7:e50554. 2012
    ..These data suggest a link between biglycan and adiponectin expression. However, the difference in the pattern of regulation between in vivo and in vitro settings reveals the complexity of this relationship...
  4. pmc Metabolic markers in Ossabaw pigs fed high fat diets enriched in regular or low α-linolenic acid soy oil
    Ramesh B Potu
    Department of Animal Sciences, Purdue University, West Lafayette, IN 47907, USA
    Nutr Metab (Lond) 10:27. 2013
    ..The study was conducted to determine the metabolic impact of the low α-linolenic acid containing soy oil...
  5. pmc Adipose tissue biglycan as a potential anti-inflammatory target of sodium salicylate in mice fed a high fat diet
    Venkata J Adapala
    Department of Animal Sciences, Purdue University, West Lafayette, IN, 47907 2054, USA
    J Inflamm (Lond) 9:15. 2012
    ..abstract:..
  6. pmc Novel anti-inflammatory role of SLPI in adipose tissue and its regulation by high fat diet
    Venkata J Adapala
    Department of Animal Sciences, Purdue University, West Lafayette, Indiana, 47907, USA
    J Inflamm (Lond) 8:5. 2011
    ..abstract:..
  7. pmc Stimulation with Peptidoglycan induces interleukin 6 and TLR2 expression and a concomitant downregulation of expression of adiponectin receptors 1 and 2 in 3T3-L1 adipocytes
    Kolapo M Ajuwon
    Department of Animal Sciences, Purdue University, West Lafayette, IN 47907, USA
    J Inflamm (Lond) 6:8. 2009
    ..Whereas it has been demonstrated that adipocytes respond to TLR4 stimulation with lipopolysacccharide, very little is known about their response to the TLR2 agonist, peptidoglycan...
  8. ncbi request reprint Adiponectin inhibits LPS-induced NF-kappaB activation and IL-6 production and increases PPARgamma2 expression in adipocytes
    Kolapo M Ajuwon
    Department of Animal Sciences, Comparative Medicine Center, Purdue Univ, 3 230 Lilly Hall of Life Sciences, 915 W State St, West Lafayette, IN 47907 2054, USA
    Am J Physiol Regul Integr Comp Physiol 288:R1220-5. 2005
    ..05). These findings indicate that adiponectin may be a local regulator of inflammation in the adipocyte and adipose tissue via its regulation of the NF-kappaB and PPARgamma2 transcription factors...
  9. ncbi request reprint Chronic leptin administration increases serum NEFA in the pig and differentially regulates PPAR expression in adipose tissue
    Kolapo M Ajuwon
    Department of Animal Sciences, Purdue University, West Lafayette, IN, USA
    J Nutr Biochem 14:576-83. 2003
    ..The regulation of PPARgamma by leptin seems complex in that it varied in relation to dose in vivo, and may be impacted by in vitro vs. in vivo circumstances...
  10. ncbi request reprint Adiponectin differentially regulates cytokines in porcine macrophages
    Meghan C Wulster-Radcliffe
    Department of Animal Sciences, Comparative Medicine Program, Purdue University, West Lafayette, IN, USA
    Biochem Biophys Res Commun 316:924-9. 2004
    ..In addition, we provide evidence that some of the anti-inflammatory actions of adiponectin are mediated in part by suppression of NFkappaB signaling and ERK1/2 activity...
  11. doi request reprint Regulation of adipocyte differentiation and gene expression-crosstalk between TGFβ and wnt signaling pathways
    Hang Lu
    Department of Animal Sciences, Purdue University, 915 W State Street, West Lafayette, IN 47907 2054, USA
    Mol Biol Rep 40:5237-45. 2013
    ....
  12. ncbi request reprint Direct regulation of lipolysis by interleukin-15 in primary pig adipocytes
    Kolapo M Ajuwon
    Department of Animal Sciences, Comparative Medicine Program, Purdue University, Lilly Hall of Life Sciences, 915 W State St, West Lafayette, IN 47907 2054, USA
    Am J Physiol Regul Integr Comp Physiol 287:R608-11. 2004
    ..Thus, when induced by IFN-gamma or other inflammatory mediators, IL-15 may be a significant homeorhetic factor that mobilizes and directs energy away from the adipocyte to other cells during the acute phase of the inflammatory response...
  13. ncbi request reprint Palmitate activates the NF-kappaB transcription factor and induces IL-6 and TNFalpha expression in 3T3-L1 adipocytes
    Kolapo M Ajuwon
    Department of Animal Sciences, Center for Comparative Medicine, Purdue University, West Lafayette, IN 47907 2054, USA
    J Nutr 135:1841-6. 2005
    ..Furthermore, PI3K may act constitutively to suppress inflammation. Consequently, inhibition of this enzyme may promote and exacerbate the inflammation in adipose tissue that is associated with obesity and insulin resistance...
  14. ncbi request reprint Interleukin-6 and interleukin-15 are selectively regulated by lipopolysaccharide and interferon-gamma in primary pig adipocytes
    Kolapo M Ajuwon
    Department of Animal Sciences, Comparative Medicine Program, Purdue University, West Lafayette, Indiana 47907 2054, USA
    Am J Physiol Regul Integr Comp Physiol 286:R547-53. 2004
    ....
  15. ncbi request reprint The regulation of IGF-1 by leptin in the pig is tissue specific and independent of changes in growth hormone
    Kolapo M Ajuwon
    Department of Animal Sciences, Purdue University, West Lafayette, IN, USA
    J Nutr Biochem 14:522-30. 2003
    ..Collectively, these data indicate that leptin may regulate hepatic IGF-1 production in the pig, independent of GH, but that hepatocyte sensitivity to leptin may be depend on dose and in vitro vs. in vivo conditions...
  16. doi request reprint Acute inflammation plays a limited role in the regulation of adipose tissue COL1A1 protein abundance
    Venkata J Adapala
    Department of Animal Sciences, Purdue University, West Lafayette, IN 47907 2054, USA
    J Nutr Biochem 23:567-72. 2012
    ..Elevated MMP9 gelatinolytic activity in SWAT from obese humans indicates a prominent role for MMP9 in SWAT COL1A1 protein turnover in humans...