Sherrill Slichter

Summary

Affiliation: Puget Sound Blood Center
Country: USA

Publications

  1. pmc Factors affecting posttransfusion platelet increments, platelet refractoriness, and platelet transfusion intervals in thrombocytopenic patients
    Sherrill J Slichter
    Puget Sound Blood Center, Seattle, WA 98104 1256, USA
    Blood 105:4106-14. 2005
  2. ncbi request reprint Platelet transfusion therapy
    Sherrill J Slichter
    Puget Sound Blood Center, 921 Terry Avenue, Seattle, WA 98104 1256, USA
    Hematol Oncol Clin North Am 21:697-729, vii. 2007
  3. pmc Extended storage of autologous apheresis platelets in plasma
    S J Slichter
    Puget Sound Blood Center, Seattle, WA 98104 1256, USA
    Vox Sang 104:324-30. 2013
  4. pmc Platelet concentrates prepared after a 20- to 24-hour hold of the whole blood at 22°C
    Sherrill J Slichter
    Puget Sound Blood Center and University of Washington School of Medicine, Seattle, Washington 98104 1256, USA
    Transfusion 52:2043-8. 2012
  5. ncbi request reprint Platelets photochemically treated with amotosalen HCl and ultraviolet A light correct prolonged bleeding times in patients with thrombocytopenia
    Sherrill J Slichter
    Puget Sound Blood Center, Seattle, Washington 98104 1256, USA
    Transfusion 46:731-40. 2006
  6. ncbi request reprint Viability and function of 8-day-stored apheresis platelets
    Sherrill J Slichter
    Puget Sound Blood Center, Seattle, Washington 98104 1256, USA
    Transfusion 46:1763-9. 2006
  7. doi request reprint Effects of pretransfusion warming of platelets to 35 degrees C on posttransfusion platelet viability
    Sherrill J Slichter
    Platelet Transfusion Research, Puget Sound Blood Center, 921 Terry Avenue, Seattle, WA 98104 1256, USA
    Transfusion 49:2319-25. 2009
  8. pmc Dose of prophylactic platelet transfusions and prevention of hemorrhage
    Sherrill J Slichter
    Puget Sound Blood Center, Seattle, WA 98104 1256, USA
    N Engl J Med 362:600-13. 2010
  9. pmc Extended storage of platelet-rich plasma-prepared platelet concentrates in plasma or Plasmalyte
    Sherrill J Slichter
    Puget Sound Blood Center and the University of Washington School of Medicine, Seattle, Washington 98104 1256, USA
    Transfusion 50:2199-209. 2010
  10. doi request reprint New thoughts on the correct dosing of prophylactic platelet transfusions to prevent bleeding
    Sherrill J Slichter
    Puget Sound Blood Center, Seattle, Washington 98104 1256, USA
    Curr Opin Hematol 18:427-35. 2011

Research Grants

  1. NOVEL APPROACHES TO IMPROVE AND EXTEND PLATELET STORAGE
    Sherrill Slichter; Fiscal Year: 2001
  2. TRANSFUSION MEDICINE/HEMOSTASIS TRAIL SITE AT PSBC
    Sherrill Slichter; Fiscal Year: 2007
  3. BIOLOGIC AND IMMUNOLOGIC ASPECTS OF TRANSFUSION MEDICINE
    Sherrill Slichter; Fiscal Year: 2007

Detail Information

Publications25

  1. pmc Factors affecting posttransfusion platelet increments, platelet refractoriness, and platelet transfusion intervals in thrombocytopenic patients
    Sherrill J Slichter
    Puget Sound Blood Center, Seattle, WA 98104 1256, USA
    Blood 105:4106-14. 2005
    ..The only factors that reduced platelet refractoriness rates were increasing the dose of platelets transfused or transfusing filtered apheresis platelets...
  2. ncbi request reprint Platelet transfusion therapy
    Sherrill J Slichter
    Puget Sound Blood Center, 921 Terry Avenue, Seattle, WA 98104 1256, USA
    Hematol Oncol Clin North Am 21:697-729, vii. 2007
    ..Identification, prevention, and management of adverse consequences of platelet transfusions and platelet refractoriness are discussed...
  3. pmc Extended storage of autologous apheresis platelets in plasma
    S J Slichter
    Puget Sound Blood Center, Seattle, WA 98104 1256, USA
    Vox Sang 104:324-30. 2013
    ..The purpose of our studies was to determine the effects of extended platelet storage on poststorage platelet viability...
  4. pmc Platelet concentrates prepared after a 20- to 24-hour hold of the whole blood at 22°C
    Sherrill J Slichter
    Puget Sound Blood Center and University of Washington School of Medicine, Seattle, Washington 98104 1256, USA
    Transfusion 52:2043-8. 2012
    ..The Food and Drug Administration (FDA) requires that red blood cells must be refrigerated within 8 hours of whole blood collection. Longer storage of whole blood at 22°C before component preparation would have many advantages...
  5. ncbi request reprint Platelets photochemically treated with amotosalen HCl and ultraviolet A light correct prolonged bleeding times in patients with thrombocytopenia
    Sherrill J Slichter
    Puget Sound Blood Center, Seattle, Washington 98104 1256, USA
    Transfusion 46:731-40. 2006
    ..Photochemical treatment (PCT) with amotosalen HCl with ultraviolet A illumination inactivates pathogens and white blood cells in platelet (PLT) concentrates...
  6. ncbi request reprint Viability and function of 8-day-stored apheresis platelets
    Sherrill J Slichter
    Puget Sound Blood Center, Seattle, Washington 98104 1256, USA
    Transfusion 46:1763-9. 2006
    ..Methods of bacterial detection and pathogen inactivation of platelets (PLTs) may allow extended storage of PLTs as long as PLT quality is maintained...
  7. doi request reprint Effects of pretransfusion warming of platelets to 35 degrees C on posttransfusion platelet viability
    Sherrill J Slichter
    Platelet Transfusion Research, Puget Sound Blood Center, 921 Terry Avenue, Seattle, WA 98104 1256, USA
    Transfusion 49:2319-25. 2009
    ..Three of four prior studies suggested that warming platelets (PLTs) to 37 degrees C before transfusion into patients with thrombocytopenia gave improved corrected PLT count increments...
  8. pmc Dose of prophylactic platelet transfusions and prevention of hemorrhage
    Sherrill J Slichter
    Puget Sound Blood Center, Seattle, WA 98104 1256, USA
    N Engl J Med 362:600-13. 2010
    ..We conducted a trial of prophylactic platelet transfusions to evaluate the effect of platelet dose on bleeding in patients with hypoproliferative thrombocytopenia...
  9. pmc Extended storage of platelet-rich plasma-prepared platelet concentrates in plasma or Plasmalyte
    Sherrill J Slichter
    Puget Sound Blood Center and the University of Washington School of Medicine, Seattle, Washington 98104 1256, USA
    Transfusion 50:2199-209. 2010
    ..The Food and Drug Administration (FDA)'s poststorage PLT acceptance guidelines are that autologous stored PLT recoveries and survivals should be 66 and 58% or greater, respectively, of each donor's fresh PLT data...
  10. doi request reprint New thoughts on the correct dosing of prophylactic platelet transfusions to prevent bleeding
    Sherrill J Slichter
    Puget Sound Blood Center, Seattle, Washington 98104 1256, USA
    Curr Opin Hematol 18:427-35. 2011
    ..Recent studies have evaluated the effects of platelet dose on hemostasis...
  11. ncbi request reprint Background, rationale, and design of a clinical trial to assess the effects of platelet dose on bleeding risk in thrombocytopenic patients
    Sherrill J Slichter
    Puget Sound Blood Center, 921 Terry Avenue, Seattle, Washington 98104 1256, USA
    J Clin Apher 21:78-84. 2006
    ....
  12. ncbi request reprint Understanding the effects of different types of white cells on patient's responses to transfusion: immunization versus tolerization
    Sherrill J Slichter
    Puget Sound Blood Center, and University of Washington School of Medicine, Seattle, WA, USA
    Vox Sang 83:421-4. 2002
  13. ncbi request reprint Platelet transfusion: future directions
    S J Slichter
    Executive Vice President of Research, Puget Sound Blood Center Professor of Medicine, University of Washington School of Medicine, Seattle, Washington 98104 1256, USA
    Vox Sang 87:47-51. 2004
  14. ncbi request reprint Relationship between platelet count and bleeding risk in thrombocytopenic patients
    Sherrill J Slichter
    Puget Sound Blood Center, University of Washington School of Medicine, Seattle 98104 01256, USA
    Transfus Med Rev 18:153-67. 2004
    ..Therapeutic platelet transfusions have been documented to control bleeding, and mortality rates are not increased when comparing patients receiving therapeutic to that seen in patients receiving prophylactic platelet transfusions...
  15. ncbi request reprint Evaluation of different methods of leukoreduction of donor platelets to prevent alloimmune platelet refractoriness and induce tolerance in a canine transfusion model
    Sherrill J Slichter
    Puget Sound Blood Center, Seattle, WA 98104 1256, USA
    Blood 105:847-54. 2005
    ..These data suggest that some allostimulatory white cells are filter adherent, whereas others escape filtration but can be removed by centrifugation and tolerance requires a residual functioning white cell...
  16. ncbi request reprint Recombinant human macrophage colony-stimulating factor-induced thrombocytopenia in dogs
    Kraig Abrams
    Puget Sound Blood Center, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA 98109 1024, USA
    Br J Haematol 121:614-22. 2003
    ..18; n = 4). These results support the concept that rhM-CSF induces an activation of the monocyte-macrophage system (MMS), which causes a reversible TCP in a dog model...
  17. doi request reprint A systematic assessment of the quality of reporting for platelet transfusion studies
    Meghan Delaney
    Puget Sound Blood Center, Seattle, Washington 98104, USA
    Transfusion 50:2135-44. 2010
    ..A recent review of clinical platelet (PLT) studies indicated variability in reporting. We undertook a critical analysis of PLT transfusion studies to determine the quality of reporting...
  18. ncbi request reprint Therapeutic efficacy and safety of platelets treated with a photochemical process for pathogen inactivation: the SPRINT Trial
    Jeffrey McCullough
    University of Minnesota, MMC 609, 420 Delaware Street SE, Minneapolis, MN 55455, USA
    Blood 104:1534-41. 2004
    ..02). The incidence of grade 2 bleeding was equivalent for PCT and conventional platelets, although posttransfusion platelet count increments and days to next transfusion were decreased for PCT compared with conventional platelets...
  19. ncbi request reprint Galactosylation does not prevent the rapid clearance of long-term, 4 degrees C-stored platelets
    Hans H Wandall
    ZymeQuest, Beverly, MA, USA
    Blood 111:3249-56. 2008
    ..We conclude that different mechanisms of clearance may exist for short- and long-term cold-stored platelets...
  20. ncbi request reprint In vitro pH effects on in vivo recovery and survival of platelets: an analysis by the BEST Collaborative
    Larry J Dumont
    Gambro BCT, Lakewood, CO, USA
    Transfusion 46:1300-5. 2006
    ..The objective of this study was to evaluate the effect of in vitro pH on the in vivo recovery and survival of autologous PLT products...
  21. ncbi request reprint A descriptive analysis of international transfusion practice and bleeding outcomes in patients with acute leukemia
    Nancy M Heddle
    Department of Medicine, McMaster University, Canadian Blood Services, Hamilton, Ontario, Canada, and the Transfusion and Transplant Immunology Center IRCCS, Maggiore Hospital, Milan, Italy
    Transfusion 46:903-11. 2006
    ..The purpose of this study was to provide a descriptive summary of data from PLT studies conducted in four countries and exploratory analyses to determine the relationship between bleeding and PLT count...
  22. ncbi request reprint Clinical safety of platelets photochemically treated with amotosalen HCl and ultraviolet A light for pathogen inactivation: the SPRINT trial
    Edward Snyder
    Yale University Medical School, Yale New Haven Hospital, New Haven, Connecticut, USA
    Transfusion 45:1864-75. 2005
    ..Hemostatic equivalency was demonstrated. The proportion of patients with Grade 2 bleeding was not inferior for PCT PLTs...
  23. ncbi request reprint Platelet dose consistency and its effect on the number of platelet transfusions for support of thrombocytopenia: an analysis of the SPRINT trial of platelets photochemically treated with amotosalen HCl and ultraviolet A light
    Scott Murphy
    American Red Cross Blood Services, Philadelphia, Pennsylvania, USA
    Transfusion 46:24-33. 2006
    ..PLT dose was analyzed to determine the impact of the number of PLTs transfused on transfusion requirements...
  24. ncbi request reprint Comparison of computerized formulae for determination of platelet recovery and survival
    James P AuBuchon
    Transfusion 45:1237-9. 2005
  25. ncbi request reprint Factors influencing moderate to severe reactions to PLT transfusions: experience of the TRAP multicenter clinical trial
    Helen Enright
    University of Minnesota School of Medicine, Minneapolis, Minnesota, USA
    Transfusion 43:1545-52. 2003
    ..During the Trial to Reduce Alloimmunization to Platelets (TRAP Trial), data were prospectively collected for 8769 PLT transfusions regarding the frequency of moderate to severe PLT transfusion reactions...

Research Grants8

  1. NOVEL APPROACHES TO IMPROVE AND EXTEND PLATELET STORAGE
    Sherrill Slichter; Fiscal Year: 2001
    ....
  2. TRANSFUSION MEDICINE/HEMOSTASIS TRAIL SITE AT PSBC
    Sherrill Slichter; Fiscal Year: 2007
    ..We are still working with the Hemophilia specialist (Dr. Dana Matthews) at our Childrens Hospital to determine if she is willing to enroll patients in the RICH trial. PUGET SOUND BLOOD CENTER CRITIQUES ..
  3. BIOLOGIC AND IMMUNOLOGIC ASPECTS OF TRANSFUSION MEDICINE
    Sherrill Slichter; Fiscal Year: 2007
    ..End of Abstract) ..