Affiliation: Psychiatric Genomics
- The mood stabilizer valproic acid stimulates GABA neurogenesis from rat forebrain stem cellsPascal Laeng
Gene Discovery, Psychiatric Genomics, Inc, Gaithersburg, Maryland 20878, USA
J Neurochem 91:238-51. 2004....
- Comparison of microarray-based mRNA profiling technologies for identification of psychiatric disease and drug signaturesLinda W Jurata
Psychiatric Genomics Inc, 19 Firstfield Road, Gaithersburg, MD 20878, USA
J Neurosci Methods 138:173-88. 2004..The modest overlap but similar validation rates show that each microarray system identifies a unique set of differentially expressed genes, and thus the greatest information is obtained from the use of both platforms...
- Insulin, IGF-1, and muscarinic agonists modulate schizophrenia-associated genes in human neuroblastoma cellsC Anthony Altar
Psychiatric Genomics, Inc, Gaithersburg, Maryland, USA
Biol Psychiatry 64:1077-87. 2008..We determined with human SH-SY5Y neuroblastoma and astrocyte cell lines whether insulin or other molecules could modulate genes opposite to their change reported in schizophrenia brain...
- Electroconvulsive seizures regulate gene expression of distinct neurotrophic signaling pathwaysC Anthony Altar
Psychiatric Genomics, Gaithersburg, Maryland 20878, USA
J Neurosci 24:2667-77. 2004..These genes, and others that increase only with chronic ECS such as neuropeptide Y and thyrotropin-releasing hormone, may provide novel ways to select drugs for the treatment of depression and mimic the rapid effectiveness of ECT...