Aleksandra M Walczak

Summary

Affiliation: Princeton University
Country: USA

Publications

  1. pmc A stochastic spectral analysis of transcriptional regulatory cascades
    Aleksandra M Walczak
    Princeton Center for Theoretical Science, Princeton University, Princeton, NJ 08544, USA
    Proc Natl Acad Sci U S A 106:6529-34. 2009
  2. ncbi request reprint Optimizing information flow in small genetic networks. II. Feed-forward interactions
    Aleksandra M Walczak
    Joseph Henry Laboratories of Physics, Lewis Sigler Institute for Integrative Genomics, and Princeton Center for Theoretical Science, Princeton University, Princeton, New Jersey 08544, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 81:041905. 2010
  3. pmc Social interactions dominate speed control in poising natural flocks near criticality
    William Bialek
    Joseph Henry Laboratories of Physics and Lewis Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544
    Proc Natl Acad Sci U S A 111:7212-7. 2014
  4. pmc Statistical inference of the generation probability of T-cell receptors from sequence repertoires
    Anand Murugan
    Joseph Henry Laboratories, Princeton University, Princeton, NJ 08544, USA
    Proc Natl Acad Sci U S A 109:16161-6. 2012
  5. pmc Statistical mechanics for natural flocks of birds
    William Bialek
    Joseph Henry Laboratories of Physics and Lewis Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA
    Proc Natl Acad Sci U S A 109:4786-91. 2012
  6. pmc Gene-gene cooperativity in small networks
    Aleksandra M Walczak
    Princeton Center for Theoretical Science, Princeton University, Princeton, New Jersey, USA
    Biophys J 96:4525-41. 2009
  7. pmc Maximum entropy models for antibody diversity
    Thierry Mora
    Joseph Henry Laboratories of Physics and Lewis Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA
    Proc Natl Acad Sci U S A 107:5405-10. 2010

Collaborators

  • Andrew Mugler
  • Gasper Tkacik
  • William Bialek
  • Thierry Mora
  • Massimiliano Viale
  • Irene Giardina
  • Andrea Cavagna
  • Edmondo Silvestri
  • Anand Murugan
  • Curtis G Callan
  • Oliver Pohl

Detail Information

Publications7

  1. pmc A stochastic spectral analysis of transcriptional regulatory cascades
    Aleksandra M Walczak
    Princeton Center for Theoretical Science, Princeton University, Princeton, NJ 08544, USA
    Proc Natl Acad Sci U S A 106:6529-34. 2009
    ..We anticipate that this numerical approach may be useful for modeling noise in a variety of small network topologies in biology...
  2. ncbi request reprint Optimizing information flow in small genetic networks. II. Feed-forward interactions
    Aleksandra M Walczak
    Joseph Henry Laboratories of Physics, Lewis Sigler Institute for Integrative Genomics, and Princeton Center for Theoretical Science, Princeton University, Princeton, New Jersey 08544, USA
    Phys Rev E Stat Nonlin Soft Matter Phys 81:041905. 2010
    ..Even with this limitation, the networks that optimize information transmission have a structure reminiscent of the networks found in real biological systems...
  3. pmc Social interactions dominate speed control in poising natural flocks near criticality
    William Bialek
    Joseph Henry Laboratories of Physics and Lewis Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544
    Proc Natl Acad Sci U S A 111:7212-7. 2014
    ..In biological terms, criticality allows the flock to achieve maximal correlation across long distances with limited speed fluctuations...
  4. pmc Statistical inference of the generation probability of T-cell receptors from sequence repertoires
    Anand Murugan
    Joseph Henry Laboratories, Princeton University, Princeton, NJ 08544, USA
    Proc Natl Acad Sci U S A 109:16161-6. 2012
    ..We argue that the use of formal statistical inference methods, of the kind presented in this paper, will be essential for quantitative understanding of the generation and evolution of diversity in the adaptive immune system...
  5. pmc Statistical mechanics for natural flocks of birds
    William Bialek
    Joseph Henry Laboratories of Physics and Lewis Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA
    Proc Natl Acad Sci U S A 109:4786-91. 2012
    ..Finally, by comparing flocks of different sizes, the model correctly accounts for the observed scale invariance of long-range correlations among the fluctuations in flight direction...
  6. pmc Gene-gene cooperativity in small networks
    Aleksandra M Walczak
    Princeton Center for Theoretical Science, Princeton University, Princeton, New Jersey, USA
    Biophys J 96:4525-41. 2009
    ....
  7. pmc Maximum entropy models for antibody diversity
    Thierry Mora
    Joseph Henry Laboratories of Physics and Lewis Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA
    Proc Natl Acad Sci U S A 107:5405-10. 2010
    ..This approach should be applicable to the study of the global properties of other protein families...