Pankaj Mehta

Summary

Affiliation: Princeton University
Country: USA

Publications

  1. doi request reprint Exponential sensitivity of noise-driven switching in genetic networks
    Pankaj Mehta
    Department of Molecular Biology and Department of Physics, Princeton University, Princeton, NJ 08544, USA
    Phys Biol 5:026005. 2008
  2. pmc A quantitative comparison of sRNA-based and protein-based gene regulation
    Pankaj Mehta
    Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA
    Mol Syst Biol 4:221. 2008
  3. pmc Information processing and signal integration in bacterial quorum sensing
    Pankaj Mehta
    Department of Molecular Biology, Lewis Thomas Laboratory, Princeton University, Princeton, NJ 08540, USA
    Mol Syst Biol 5:325. 2009
  4. pmc Active regulation of receptor ratios controls integration of quorum-sensing signals in Vibrio harveyi
    Shu Wen Teng
    Department of Physics, Princeton University, Princeton, NJ, USA
    Mol Syst Biol 7:491. 2011
  5. pmc Measurement of the copy number of the master quorum-sensing regulator of a bacterial cell
    Shu Wen Teng
    Department of Physics, Princeton University, Princeton, New Jersey, USA
    Biophys J 98:2024-31. 2010
  6. pmc Quantifying the integration of quorum-sensing signals with single-cell resolution
    Tao Long
    Department of Physics, Princeton University, Princeton, NJ, USA
    PLoS Biol 7:e68. 2009

Collaborators

Detail Information

Publications6

  1. doi request reprint Exponential sensitivity of noise-driven switching in genetic networks
    Pankaj Mehta
    Department of Molecular Biology and Department of Physics, Princeton University, Princeton, NJ 08544, USA
    Phys Biol 5:026005. 2008
    ..Exponential sensitivity limits the robustness of noise-driven switching, suggesting cells may use other mechanisms in order to switch reliably. We discuss our results in the context of competence in the bacterium Bacillus subtilis...
  2. pmc A quantitative comparison of sRNA-based and protein-based gene regulation
    Pankaj Mehta
    Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA
    Mol Syst Biol 4:221. 2008
    ..This functional niche is consistent with the widespread appearance of sRNAs in stress response and quasi-developmental networks in prokaryotes...
  3. pmc Information processing and signal integration in bacterial quorum sensing
    Pankaj Mehta
    Department of Molecular Biology, Lewis Thomas Laboratory, Princeton University, Princeton, NJ 08540, USA
    Mol Syst Biol 5:325. 2009
    ..Here, we analyze two such strategies: manipulation of autoinducer production and feedback on receptor number ratios...
  4. pmc Active regulation of receptor ratios controls integration of quorum-sensing signals in Vibrio harveyi
    Shu Wen Teng
    Department of Physics, Princeton University, Princeton, NJ, USA
    Mol Syst Biol 7:491. 2011
    ..We conclude that V. harveyi employs multiple feedback loops to simultaneously control quorum-sensing signal integration and to ensure signal transmission fidelity...
  5. pmc Measurement of the copy number of the master quorum-sensing regulator of a bacterial cell
    Shu Wen Teng
    Department of Physics, Princeton University, Princeton, New Jersey, USA
    Biophys J 98:2024-31. 2010
    ..Combining the static and time-lapse experiments, we determine the magnitude of the Fano factor of the distribution. This technique has broad applicability as a general in vivo technique for measuring protein copy number and burst size...
  6. pmc Quantifying the integration of quorum-sensing signals with single-cell resolution
    Tao Long
    Department of Physics, Princeton University, Princeton, NJ, USA
    PLoS Biol 7:e68. 2009
    ..We speculate that the use of multiple autoinducers allows a growing population of cells to synchronize gene expression during a series of distinct developmental stages...