R D Knight

Summary

Affiliation: Princeton University
Country: USA

Publications

  1. ncbi request reprint Rewiring the keyboard: evolvability of the genetic code
    R D Knight
    Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey 08544, USA
    Nat Rev Genet 2:49-58. 2001
  2. pmc A simple model based on mutation and selection explains trends in codon and amino-acid usage and GC composition within and across genomes
    R D Knight
    Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA
    Genome Biol 2:RESEARCH0010. 2001
  3. ncbi request reprint The molecular basis of nuclear genetic code change in ciliates
    C A Lozupone
    Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA
    Curr Biol 11:65-74. 2001
  4. ncbi request reprint How mitochondria redefine the code
    R D Knight
    Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA
    J Mol Evol 53:299-313. 2001

Collaborators

Detail Information

Publications4

  1. ncbi request reprint Rewiring the keyboard: evolvability of the genetic code
    R D Knight
    Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey 08544, USA
    Nat Rev Genet 2:49-58. 2001
    ..The majority of non-standard codes arise from alterations in the tRNA, with most occurring by post-transcriptional modifications, such as base modification or RNA editing, rather than by substitutions within tRNA anticodons...
  2. pmc A simple model based on mutation and selection explains trends in codon and amino-acid usage and GC composition within and across genomes
    R D Knight
    Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA
    Genome Biol 2:RESEARCH0010. 2001
    ..Thus, the model may be useful in predicting amino-acid or nucleotide sequences in poorly characterized taxa...
  3. ncbi request reprint The molecular basis of nuclear genetic code change in ciliates
    C A Lozupone
    Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA
    Curr Biol 11:65-74. 2001
    ..The strong concordance with biochemical data indicates that our methodology may be generally useful for detecting molecular determinants of biochemical changes in evolution...
  4. ncbi request reprint How mitochondria redefine the code
    R D Knight
    Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA
    J Mol Evol 53:299-313. 2001
    ..Ambiguity can act alone but often acts in concert with codon disappearance, which promotes codon reassignment...