Zia Khan

Summary

Affiliation: Princeton University
Country: USA

Publications

  1. pmc Protein quantification across hundreds of experimental conditions
    Zia Khan
    Department of Computer Science, Lewis Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08540, USA
    Proc Natl Acad Sci U S A 106:15544-8. 2009
  2. pmc Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS
    Zia Khan
    Department of Computer Science, Princeton University, Princeton, NJ 08544, USA
    Mol Syst Biol 8:602. 2012
  3. pmc Accurate proteome-wide protein quantification from high-resolution 15N mass spectra
    Zia Khan
    Lewis Sigler Institute for Integrative Genomics, Princeton University, Washington Rd, Princeton, NJ 08544, USA
    Genome Biol 12:R122. 2011
  4. pmc Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays
    Joshua S Bloom
    Lewis Sigler Institute of Integrative Genomics, Princeton University, New Jersey, USA
    BMC Genomics 10:221. 2009
  5. pmc Global secretome analysis identifies novel mediators of bone metastasis
    Mario Andres Blanco
    Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA
    Cell Res 22:1339-55. 2012
  6. pmc A practical algorithm for finding maximal exact matches in large sequence datasets using sparse suffix arrays
    Zia Khan
    Department of Computer Science, Lewis Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA
    Bioinformatics 25:1609-16. 2009
  7. pmc Stable Isotope Labeling of Phosphoproteins for Large-scale Phosphorylation Rate Determination
    Rosalynn C Molden
    Department of Chemistry, Frick Laboratory, Princeton University, Princeton, New Jersey 08544
    Mol Cell Proteomics 13:1106-18. 2014
  8. pmc Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization
    Manav Korpal
    Department of Molecular Biology, Princeton University, Princeton, New Jersey, USA
    Nat Med 17:1101-8. 2011

Detail Information

Publications8

  1. pmc Protein quantification across hundreds of experimental conditions
    Zia Khan
    Department of Computer Science, Lewis Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08540, USA
    Proc Natl Acad Sci U S A 106:15544-8. 2009
    ..We demonstrate the scalability of these techniques by applying them to a large dataset that comprises a total of 472 experimental conditions and replicates...
  2. pmc Quantitative measurement of allele-specific protein expression in a diploid yeast hybrid by LC-MS
    Zia Khan
    Department of Computer Science, Princeton University, Princeton, NJ 08544, USA
    Mol Syst Biol 8:602. 2012
    ..Our results provide the first analysis of the relative contribution of cis-acting and trans-acting regulatory differences to protein expression divergence between yeast species...
  3. pmc Accurate proteome-wide protein quantification from high-resolution 15N mass spectra
    Zia Khan
    Lewis Sigler Institute for Integrative Genomics, Princeton University, Washington Rd, Princeton, NJ 08544, USA
    Genome Biol 12:R122. 2011
    ..Application of this method to an Escherichia coli growth transition reveals significant improvement in quantification accuracy over previous methods...
  4. pmc Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays
    Joshua S Bloom
    Lewis Sigler Institute of Integrative Genomics, Princeton University, New Jersey, USA
    BMC Genomics 10:221. 2009
    ..High-throughput cDNA synthesis and sequencing of poly(A)-enriched RNA is rapidly emerging as a technology competing to replace microarrays as a quantitative platform for measuring gene expression...
  5. pmc Global secretome analysis identifies novel mediators of bone metastasis
    Mario Andres Blanco
    Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA
    Cell Res 22:1339-55. 2012
    ..Overall, our study has uncovered several new secreted mediators of bone metastasis and therefore demonstrated that secretome analysis is a powerful method for identification of novel biomarkers and candidate therapeutic targets...
  6. pmc A practical algorithm for finding maximal exact matches in large sequence datasets using sparse suffix arrays
    Zia Khan
    Department of Computer Science, Lewis Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA
    Bioinformatics 25:1609-16. 2009
    ....
  7. pmc Stable Isotope Labeling of Phosphoproteins for Large-scale Phosphorylation Rate Determination
    Rosalynn C Molden
    Department of Chemistry, Frick Laboratory, Princeton University, Princeton, New Jersey 08544
    Mol Cell Proteomics 13:1106-18. 2014
    ..The data have been deposited to the ProteomeXchange with the identifier PXD000680. ..
  8. pmc Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization
    Manav Korpal
    Department of Molecular Biology, Princeton University, Princeton, New Jersey, USA
    Nat Med 17:1101-8. 2011
    ..Overall, these findings suggest a pleiotropic role of miR-200s in promoting metastatic colonization by influencing E-cadherin-dependent epithelial traits and Sec23a-mediated tumor cell secretome...