K Hagstrom

Summary

Affiliation: Princeton University
Country: USA

Publications

  1. pmc A Polycomb and GAGA dependent silencer adjoins the Fab-7 boundary in the Drosophila bithorax complex
    K Hagstrom
    Department of Molecular Biology, Princeton University, New Jersey 08544, USA
    Genetics 146:1365-80. 1997
  2. ncbi request reprint Remembrance of things past: maintaining gene expression patterns with altered chromatin
    K Hagstrom
    Department of Molecular Biology, Princeton University, New Jersey 08544, USA
    Curr Opin Genet Dev 7:814-21. 1997
  3. pmc The mcp element from the Drosophila melanogaster bithorax complex mediates long-distance regulatory interactions
    M Muller
    Department of Molecular Biology, Princeton University, Princeton, New Jersey 08540, USA
    Genetics 153:1333-56. 1999
  4. ncbi request reprint Fab-7 functions as a chromatin domain boundary to ensure proper segment specification by the Drosophila bithorax complex
    K Hagstrom
    Department of Molecular Biology, Princeton University, New Jersey 08544, USA
    Genes Dev 10:3202-15. 1996
  5. ncbi request reprint Genetic and molecular analysis of chromatin domains
    J Vazquez
    Department of Molecular Biology, Princeton University, New Jersey 08544
    Cold Spring Harb Symp Quant Biol 58:45-54. 1993
  6. ncbi request reprint Chromatin domain boundaries in the Bithorax complex
    J Mihaly
    Department of Zoology and Animal Biology, University of Geneva, Switzerland
    Cell Mol Life Sci 54:60-70. 1998
  7. ncbi request reprint The Fab-8 boundary defines the distal limit of the bithorax complex iab-7 domain and insulates iab-7 from initiation elements and a PRE in the adjacent iab-8 domain
    S Barges
    Department of Zoology and Animal Biology, University of Geneva, CH 1211 Geneva 4, Switzerland
    Development 127:779-90. 2000
  8. pmc The iab-7 polycomb response element maps to a nucleosome-free region of chromatin and requires both GAGA and pleiohomeotic for silencing activity
    R K Mishra
    D├ępartement de Zoologie et Biologie Animale, Universite de Geneve, 1211 Geneva 4, Switzerland
    Mol Cell Biol 21:1311-8. 2001

Collaborators

Detail Information

Publications8

  1. pmc A Polycomb and GAGA dependent silencer adjoins the Fab-7 boundary in the Drosophila bithorax complex
    K Hagstrom
    Department of Molecular Biology, Princeton University, New Jersey 08544, USA
    Genetics 146:1365-80. 1997
    ..The iab-7 PRE silencer is contained within a 0.8-kb fragment that spans a nuclease hypersensitive site, and silencing appears to depend on the chromatin remodeling protein, the GAGA factor...
  2. ncbi request reprint Remembrance of things past: maintaining gene expression patterns with altered chromatin
    K Hagstrom
    Department of Molecular Biology, Princeton University, New Jersey 08544, USA
    Curr Opin Genet Dev 7:814-21. 1997
    ..These studies suggest that, after gene activity states are selected during development, maintenance protein complexes provide a molecular memory of those states by altering a local domain of chromatin structure...
  3. pmc The mcp element from the Drosophila melanogaster bithorax complex mediates long-distance regulatory interactions
    M Muller
    Department of Molecular Biology, Princeton University, Princeton, New Jersey 08540, USA
    Genetics 153:1333-56. 1999
    ..Finally, this pairing element can also mediate long-distance interactions between enhancers and promoters, activating mini-white expression...
  4. ncbi request reprint Fab-7 functions as a chromatin domain boundary to ensure proper segment specification by the Drosophila bithorax complex
    K Hagstrom
    Department of Molecular Biology, Princeton University, New Jersey 08544, USA
    Genes Dev 10:3202-15. 1996
    ..These results support the model that Fab-7 functions as a domain boundary within the context of the bithorax complex, making Fab-7 one of the first boundary elements that is known to have an essential function in vivo...
  5. ncbi request reprint Genetic and molecular analysis of chromatin domains
    J Vazquez
    Department of Molecular Biology, Princeton University, New Jersey 08544
    Cold Spring Harb Symp Quant Biol 58:45-54. 1993
  6. ncbi request reprint Chromatin domain boundaries in the Bithorax complex
    J Mihaly
    Department of Zoology and Animal Biology, University of Geneva, Switzerland
    Cell Mol Life Sci 54:60-70. 1998
    ..Although the mechanisms by which Fab-7 works as a domain boundary remain an open issue, we provide preliminary evidence that Fab-7 is not a mere insulator like scs or the reiterated binding site for the SU(HW) protein...
  7. ncbi request reprint The Fab-8 boundary defines the distal limit of the bithorax complex iab-7 domain and insulates iab-7 from initiation elements and a PRE in the adjacent iab-8 domain
    S Barges
    Department of Zoology and Animal Biology, University of Geneva, CH 1211 Geneva 4, Switzerland
    Development 127:779-90. 2000
    ..Fab-8 together with the previously identified Fab-7 boundary delimit the first genetically defined higher order domain in a multicellular eukaryote...
  8. pmc The iab-7 polycomb response element maps to a nucleosome-free region of chromatin and requires both GAGA and pleiohomeotic for silencing activity
    R K Mishra
    D├ępartement de Zoologie et Biologie Animale, Universite de Geneve, 1211 Geneva 4, Switzerland
    Mol Cell Biol 21:1311-8. 2001
    ..We show that GAGA and Pho interact with these sequences in vitro and that the consensus binding sites for the two proteins are critical for the silencing activity of the iab-7 PRE in vivo...