J Grosshans

Summary

Affiliation: Princeton University
Country: USA

Publications

  1. ncbi request reprint Oligomerisation of Tube and Pelle leads to nuclear localisation of dorsal
    J Grosshans
    Max Planck Institut fur Entwicklungsbiologie, Abteilung III Genetik, Spemannstrasse 35 III, D 72076, Tubingen, Germany
    Mech Dev 81:127-38. 1999
  2. ncbi request reprint A genetic link between morphogenesis and cell division during formation of the ventral furrow in Drosophila
    J Grosshans
    Howard Hughes Medical Institute, Department of Molecular Biology, Princeton University, New Jersey 08540, USA
    Cell 101:523-31. 2000
  3. ncbi request reprint Activation of the kinase Pelle by Tube in the dorsoventral signal transduction pathway of Drosophila embryo
    J Grosshans
    Max Plank Institut für Entwicklungsbiologie, Abteilung III Genetik, Tubingen, Germany
    Nature 372:563-6. 1994
  4. ncbi request reprint The Drosophila proteins Pelle and Tube induce JNK/AP-1 activity in mammalian cells
    S Bacher
    German Cancer Research Center, Department of Immunochemistry G0200, Heidelberg, Germany
    FEBS Lett 497:153-8. 2001
  5. ncbi request reprint Separable and redundant regulatory determinants in Cactus mediate its dorsal group dependent degradation
    N Q Fernandez
    Department of Molecular Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Development 128:2963-74. 2001

Collaborators

Detail Information

Publications5

  1. ncbi request reprint Oligomerisation of Tube and Pelle leads to nuclear localisation of dorsal
    J Grosshans
    Max Planck Institut fur Entwicklungsbiologie, Abteilung III Genetik, Spemannstrasse 35 III, D 72076, Tubingen, Germany
    Mech Dev 81:127-38. 1999
    ....
  2. ncbi request reprint A genetic link between morphogenesis and cell division during formation of the ventral furrow in Drosophila
    J Grosshans
    Howard Hughes Medical Institute, Department of Molecular Biology, Princeton University, New Jersey 08540, USA
    Cell 101:523-31. 2000
    ..When overexpressed in a microinjection assay, Tribbles directly inhibits mitosis. We propose that Frühstart and Tribbles form a link between the morphogenetic movements and mitotic control...
  3. ncbi request reprint Activation of the kinase Pelle by Tube in the dorsoventral signal transduction pathway of Drosophila embryo
    J Grosshans
    Max Plank Institut für Entwicklungsbiologie, Abteilung III Genetik, Tubingen, Germany
    Nature 372:563-6. 1994
    ..In addition, Pelle and Tube interact directly with one another. We propose that Tube is a direct activator of the protein kinase Pelle...
  4. ncbi request reprint The Drosophila proteins Pelle and Tube induce JNK/AP-1 activity in mammalian cells
    S Bacher
    German Cancer Research Center, Department of Immunochemistry G0200, Heidelberg, Germany
    FEBS Lett 497:153-8. 2001
    ..Activation of JNK/AP-1 activity was seen upon expression of a Pelle mutant lacking its C-terminal half or by a membrane-bound and multimerised Tube protein, showing the functionality of the Drosophila proteins in mammalian cells...
  5. ncbi request reprint Separable and redundant regulatory determinants in Cactus mediate its dorsal group dependent degradation
    N Q Fernandez
    Department of Molecular Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Development 128:2963-74. 2001
    ..Strikingly, the regulatory domain of human IkappaBalpha can also direct polarized degradation of Cactus-lacZ fusion protein...