Thomas Gregor

Summary

Affiliation: Princeton University
Country: USA

Publications

  1. ncbi Diffusion and scaling during early embryonic pattern formation
    Thomas Gregor
    Howard Hughes Medical Institute, Lewis Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA
    Proc Natl Acad Sci U S A 102:18403-7. 2005
  2. ncbi Probing the limits to positional information
    Thomas Gregor
    Joseph Henry Laboratories of Physics, Princeton University, Princeton, NJ 08544, USA
    Cell 130:153-64. 2007
  3. ncbi Shape and function of the Bicoid morphogen gradient in dipteran species with different sized embryos
    Thomas Gregor
    Howard Hughes Medical Institute, Princeton University, Princeton, NJ 08544, USA
    Dev Biol 316:350-8. 2008
  4. ncbi The formation of the Bicoid morphogen gradient requires protein movement from anteriorly localized mRNA
    Shawn C Little
    Howard Hughes Medical Institute, Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America
    PLoS Biol 9:e1000596. 2011
  5. ncbi Stability and nuclear dynamics of the bicoid morphogen gradient
    Thomas Gregor
    Lewis Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey 08544, USA
    Cell 130:141-52. 2007
  6. ncbi The role of input noise in transcriptional regulation
    Gasper Tkacik
    Joseph Henry Laboratories of Physics, Lewis Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America
    PLoS ONE 3:e2774. 2008

Collaborators

Detail Information

Publications6

  1. ncbi Diffusion and scaling during early embryonic pattern formation
    Thomas Gregor
    Howard Hughes Medical Institute, Lewis Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA
    Proc Natl Acad Sci U S A 102:18403-7. 2005
    ..Our results, together with constraints imposed by the time scales of development, suggest that the mechanism for scaling is a species-specific adaptation of the Bcd lifetime...
  2. ncbi Probing the limits to positional information
    Thomas Gregor
    Joseph Henry Laboratories of Physics, Princeton University, Princeton, NJ 08544, USA
    Cell 130:153-64. 2007
    ....
  3. ncbi Shape and function of the Bicoid morphogen gradient in dipteran species with different sized embryos
    Thomas Gregor
    Howard Hughes Medical Institute, Princeton University, Princeton, NJ 08544, USA
    Dev Biol 316:350-8. 2008
    ..However, a shallow gradient was observed using eGFP-NLS, suggesting nuclear localization may be necessary but not sufficient for gradient formation...
  4. ncbi The formation of the Bicoid morphogen gradient requires protein movement from anteriorly localized mRNA
    Shawn C Little
    Howard Hughes Medical Institute, Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America
    PLoS Biol 9:e1000596. 2011
    ..We conclude that the spatial distribution of bicoid mRNA contributes to, but cannot account for, protein gradient formation, and therefore that protein movement, either active or passive, is required for gradient formation...
  5. ncbi Stability and nuclear dynamics of the bicoid morphogen gradient
    Thomas Gregor
    Lewis Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey 08544, USA
    Cell 130:141-52. 2007
    ..A new model is presented emphasizing the possible role of nuclear dynamics in shaping and scaling the gradient...
  6. ncbi The role of input noise in transcriptional regulation
    Gasper Tkacik
    Joseph Henry Laboratories of Physics, Lewis Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America
    PLoS ONE 3:e2774. 2008
    ....