J D Cohen

Summary

Affiliation: Princeton University
Country: USA

Publications

  1. ncbi request reprint Computational perspectives on dopamine function in prefrontal cortex
    Jonathan D Cohen
    Department of Psychology, Princeton University, Princeton, New Jersey 08540, USA
    Curr Opin Neurobiol 12:223-9. 2002
  2. pmc Should I stay or should I go? How the human brain manages the trade-off between exploitation and exploration
    Jonathan D Cohen
    Department of Psychology and Center for the Study of Brain, Mind and Behaviour, Princeton University, Princeton, NJ 08540, USA
    Philos Trans R Soc Lond B Biol Sci 362:933-42. 2007
  3. ncbi request reprint Context-processing deficits in schizophrenia: converging evidence from three theoretically motivated cognitive tasks
    J D Cohen
    Department of Psychiatry, University of Pittsburgh, USA
    J Abnorm Psychol 108:120-33. 1999
  4. ncbi request reprint Reward and decision
    Jonathan D Cohen
    Department of Psychology and Center for the Study of Brain, Mind and Behavior, Princeton University, Princeton, NJ 08544, USA
    Neuron 36:193-8. 2002
  5. doi request reprint Cognitive neuroscience and schizophrenia: translational research in need of a translator
    Jonathan D Cohen
    Department of Psychology and Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA
    Biol Psychiatry 64:2-3. 2008
  6. ncbi request reprint Dissociating working memory from task difficulty in human prefrontal cortex
    D M Barch
    Department of Psychiatry, University of Pittsburgh, PA 15213, USA
    Neuropsychologia 35:1373-80. 1997
  7. ncbi request reprint Anterior cingulate gyrus dysfunction and selective attention deficits in schizophrenia: [15O]H2O PET study during single-trial Stroop task performance
    C S Carter
    Department of Psychiatry, University of Pittsburgh, Western Psychiatric Institute and Clinic, PA 15213, USA
    Am J Psychiatry 154:1670-5. 1997
  8. ncbi request reprint Selective deficits in prefrontal cortex function in medication-naive patients with schizophrenia
    D M Barch
    Department of Psychology, Campus Box 1125, 1 Brookings Dr, Washington University, St Louis, MO 63130, USA
    Arch Gen Psychiatry 58:280-8. 2001
  9. ncbi request reprint Anterior cingulate cortex, error detection, and the online monitoring of performance
    C S Carter
    Western Psychiatric Institute and Clinic, School of Medicine, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Science 280:747-9. 1998
  10. ncbi request reprint Specificity of prefrontal dysfunction and context processing deficits to schizophrenia in never-medicated patients with first-episode psychosis
    Angus W MacDonald
    Department of Psychology, University of Minnesota, N219 Elliott Hall, 75 E River Rd, Minneapolis, MN 55455, USA
    Am J Psychiatry 162:475-84. 2005

Detail Information

Publications93

  1. ncbi request reprint Computational perspectives on dopamine function in prefrontal cortex
    Jonathan D Cohen
    Department of Psychology, Princeton University, Princeton, New Jersey 08540, USA
    Curr Opin Neurobiol 12:223-9. 2002
    ..Recently, computational models have tried to elucidate the specific and intricate roles of dopamine in the prefrontal cortex, at the neurophysiological, system and behavioral levels, with varying degrees of success...
  2. pmc Should I stay or should I go? How the human brain manages the trade-off between exploitation and exploration
    Jonathan D Cohen
    Department of Psychology and Center for the Study of Brain, Mind and Behaviour, Princeton University, Princeton, NJ 08540, USA
    Philos Trans R Soc Lond B Biol Sci 362:933-42. 2007
    ..Here, we provide a brief review of this work, discuss how exploration and exploitation may be mediated in the brain and highlight some promising future directions for research...
  3. ncbi request reprint Context-processing deficits in schizophrenia: converging evidence from three theoretically motivated cognitive tasks
    J D Cohen
    Department of Psychiatry, University of Pittsburgh, USA
    J Abnorm Psychol 108:120-33. 1999
    ..The significance of these findings is discussed with regard to the specificity of deficits in schizophrenia and the hypothesis concerning the neural and cognitive mechanisms that underlie these deficits...
  4. ncbi request reprint Reward and decision
    Jonathan D Cohen
    Department of Psychology and Center for the Study of Brain, Mind and Behavior, Princeton University, Princeton, NJ 08544, USA
    Neuron 36:193-8. 2002
  5. doi request reprint Cognitive neuroscience and schizophrenia: translational research in need of a translator
    Jonathan D Cohen
    Department of Psychology and Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA
    Biol Psychiatry 64:2-3. 2008
  6. ncbi request reprint Dissociating working memory from task difficulty in human prefrontal cortex
    D M Barch
    Department of Psychiatry, University of Pittsburgh, PA 15213, USA
    Neuropsychologia 35:1373-80. 1997
    ..Thus, this study established a double-dissociation between regions responsive to WM versus task difficulty, indicating a specific involvement of DLPFC and related structures in WM function...
  7. ncbi request reprint Anterior cingulate gyrus dysfunction and selective attention deficits in schizophrenia: [15O]H2O PET study during single-trial Stroop task performance
    C S Carter
    Department of Psychiatry, University of Pittsburgh, Western Psychiatric Institute and Clinic, PA 15213, USA
    Am J Psychiatry 154:1670-5. 1997
    ..The authors investigated the function of the anterior cingulate gyrus and the related neural systems that are associated with selective attention in patients with schizophrenia...
  8. ncbi request reprint Selective deficits in prefrontal cortex function in medication-naive patients with schizophrenia
    D M Barch
    Department of Psychology, Campus Box 1125, 1 Brookings Dr, Washington University, St Louis, MO 63130, USA
    Arch Gen Psychiatry 58:280-8. 2001
    ..We use functional magnetic resonance imaging to examine PFC activation in medication-naive, first-episode patients with schizophrenia during a WM, task-isolating context processing...
  9. ncbi request reprint Anterior cingulate cortex, error detection, and the online monitoring of performance
    C S Carter
    Western Psychiatric Institute and Clinic, School of Medicine, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Science 280:747-9. 1998
    ..This suggests that the ACC detects conditions under which errors are likely to occur rather than errors themselves...
  10. ncbi request reprint Specificity of prefrontal dysfunction and context processing deficits to schizophrenia in never-medicated patients with first-episode psychosis
    Angus W MacDonald
    Department of Psychology, University of Minnesota, N219 Elliott Hall, 75 E River Rd, Minneapolis, MN 55455, USA
    Am J Psychiatry 162:475-84. 2005
    ....
  11. doi request reprint Distinct neural substrates for deductive and mathematical processing
    James K Kroger
    Department of Psychology, New Mexico State University, 220 Science Hall, Las Cruces, NM 88003, USA
    Brain Res 1243:86-103. 2008
    ..Different sorts of thinking recruit separate neural substrates, and logical reasoning goes beyond linguistic regions of the brain...
  12. pmc Do humans produce the speed-accuracy trade-off that maximizes reward rate?
    Rafal Bogacz
    Center for the Study of Brain, Mind and Behavior, and Program in Applied and Computational Mathematics, Princeton University, Princeton, NJ, USA
    Q J Exp Psychol (Hove) 63:863-91. 2010
    ....
  13. ncbi request reprint Lateral and medial hypofrontality in first-episode schizophrenia: functional activity in a medication-naive state and effects of short-term atypical antipsychotic treatment
    Beth E Snitz
    Department of Psychiatry, University of Pittsburgh Medical School, USA
    Am J Psychiatry 162:2322-9. 2005
    ..A second objective was to assess short-term effects of atypical antipsychotic medication on dorsolateral prefrontal cortex and anterior cingulate cortex functioning...
  14. ncbi request reprint Semantic priming in schizophrenia: an examination of spreading activation using word pronunciation and multiple SOAs
    D M Barch
    Department of Psychiatry, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
    J Abnorm Psychol 105:592-601. 1996
    ..The failure of SCZ to display significant priming at the 950-ms SOA is consistent with a hypothesized disturbance in higher level processes...
  15. ncbi request reprint Temporal dynamics of brain activation during a working memory task
    J D Cohen
    Department of Psychology, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
    Nature 386:604-8. 1997
    ..We used the temporal resolution of this technique to examine the dynamics of regional activation, and to show that prefrontal cortex along with parietal cortex appears to play a role in active maintenance...
  16. ncbi request reprint Resting anterior cingulate activity and abnormal responses to errors in subjects with elevated depressive symptoms: a 128-channel EEG study
    Diego A Pizzagalli
    Department of Psychology, Harvard University, Cambridge, Massachusetts 02138, USA
    Hum Brain Mapp 27:185-201. 2006
    ..Because rostral ACC regions have been implicated in treatment response in depression, our findings provide initial insight into putative mechanisms fostering treatment response...
  17. ncbi request reprint Increased stroop facilitation effects in schizophrenia are not due to increased automatic spreading activation
    D M Barch
    Department of Psychiatry, University of Pittsburgh Medical School, PA 15213, USA
    Schizophr Res 39:51-64. 1999
    ..These results are inconsistent with the spreading activation hypothesis. Alternative hypotheses regarding the source of Stroop task performance deficits in schizophrenia are discussed...
  18. ncbi request reprint Functional hypofrontality and working memory dysfunction in schizophrenia
    C S Carter
    Department of Psychiatry, University of Pittsburgh, Western Psychiatric Institute and Clinic, PA 15213, USA
    Am J Psychiatry 155:1285-7. 1998
    ..Inconsistencies in the literature may reflect, in part, the fact that abnormal physiological responses in the prefrontal cortex are best identified under conditions that place well-specified functional demands on this region...
  19. ncbi request reprint The neural basis of error detection: conflict monitoring and the error-related negativity
    Nick Yeung
    Department of Psychology, Princeton University, Princeton, NJ, USA
    Psychol Rev 111:931-59. 2004
    ..It is concluded that the ERN can be explained in terms of response conflict and that monitoring for conflict may provide a simple mechanism for detecting errors...
  20. ncbi request reprint Sensitivity of electrophysiological activity from medial frontal cortex to utilitarian and performance feedback
    Sander Nieuwenhuis
    Department of Psychology, Princeton University, NJ, USA
    Cereb Cortex 14:741-7. 2004
    ..The results are consistent with the view that the two components are manifestations of the same underlying cognitive and neural process...
  21. pmc Altered emotional interference processing in affective and cognitive-control brain circuitry in major depression
    Christina L Fales
    Department of Psychology, Washington University in St Louis, St Louis, Missouri 63110, USA
    Biol Psychiatry 63:377-84. 2008
    ....
  22. ncbi request reprint The neural basis of economic decision-making in the Ultimatum Game
    Alan G Sanfey
    Center for the Study of Brain, Mind and Behavior, Princeton University, Princeton, NJ 08544, USA
    Science 300:1755-8. 2003
    ..Further, significantly heightened activity in anterior insula for rejected unfair offers suggests an important role for emotions in decision-making...
  23. ncbi request reprint Conflict monitoring and cognitive control
    M M Botvinick
    Department of Psychology, Carnegie Mellon University, Pennsylvania, USA
    Psychol Rev 108:624-52. 2001
    ..The second study implements a feedback loop connecting conflict monitoring to cognitive control, using this to simulate a number of important behavioral phenomena...
  24. pmc Pupil diameter tracks changes in control state predicted by the adaptive gain theory of locus coeruleus function
    Mark S Gilzenrat
    Princeton University, Princeton, New Jersey
    Cogn Affect Behav Neurosci 10:252-69. 2010
    ..Findings in three experiments were consistent with these predictions, suggesting that pupillometry may be useful as an index of both control state and, indirectly, locus coeruleus function...
  25. ncbi request reprint Prefrontal cortex and dynamic categorization tasks: representational organization and neuromodulatory control
    Randall C O'Reilly
    Department of Psychology, University of Colorado, Boulder, CO 80309, USA
    Cereb Cortex 12:246-57. 2002
    ..with orbital versus dorsolateral lesions supports the validity of these principles, many of which have also been useful in accounting for other frontal phenomena...
  26. ncbi request reprint ERP correlates of feedback and reward processing in the presence and absence of response choice
    Nick Yeung
    Department of Psychology, Princeton University, Princeton, NJ 08544, USA
    Cereb Cortex 15:535-44. 2005
    ....
  27. ncbi request reprint Between-task competition and cognitive control in task switching
    Nick Yeung
    Department of Psychology, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
    J Neurosci 26:1429-38. 2006
    ..These findings provide support for theories that propose a control hierarchy comprising regions responsible for maintaining task-specific information about rules or goals, and regions involved in the coordination of these goals...
  28. ncbi request reprint Stimulus modality, perceptual overlap, and the go/no-go N2
    Sander Nieuwenhuis
    Department of Psychology, Princeton University, Princeton, New Jersey, USA
    Psychophysiology 41:157-60. 2004
    ..These findings are discussed in terms of existing hypotheses of the N2, and clarify why previous studies have not found an N2 modulation in auditory go/no-go tasks...
  29. ncbi request reprint Mechanisms underlying dependencies of performance on stimulus history in a two-alternative forced-choice task
    Raymond Y Cho
    Princeton University, Princeton, New Jersey, USA
    Cogn Affect Behav Neurosci 2:283-99. 2002
    ....
  30. pmc Updating of context in working memory: an event-related potential study
    Agatha Lenartowicz
    Princeton University, Princeton, New Jersey, USA
    Cogn Affect Behav Neurosci 10:298-315. 2010
    ..We propose that the effect of context on P2 is consistent with the onset of context updating in the PFC. Subsequent components may be indicative of activation of task-relevant posterior regions and context maintenance...
  31. pmc Parsing executive processes: strategic vs. evaluative functions of the anterior cingulate cortex
    C S Carter
    Department of Psychiatry, University of Pittsburgh, Western Psychiatric Institute and Clinics, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Proc Natl Acad Sci U S A 97:1944-8. 2000
    ..Instead, it suggests that the ACC serves an evaluative function, detecting cognitive states such as response competition, which may lead to poor performance, and representing the knowledge that strategic processes need to be engaged...
  32. pmc Independent component analysis for brain fMRI does not select for independence
    I DAUBECHIES
    Center for the Study of Brain, Mind and Behavior, Princeton University, Princeton, NJ 08544, USA
    Proc Natl Acad Sci U S A 106:10415-22. 2009
    ..The mathematical design of better analysis tools for brain fMRI should thus emphasize other mathematical characteristics than independence...
  33. ncbi request reprint An fMRI investigation of emotional engagement in moral judgment
    J D Greene
    Center for the Study of Brain, Mind, and Behavior, Department of Philosophy, 1879 Hall, Princeton University, Princeton, NJ 08544, USA
    Science 293:2105-8. 2001
    ..These results may shed light on some puzzling patterns in moral judgment observed by contemporary philosophers...
  34. pmc Sequential effects in two-choice reaction time tasks: decomposition and synthesis of mechanisms
    Juan Gao
    Department of Mechanical and Aerospace Engineering and Princeton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA
    Neural Comput 21:2407-36. 2009
    ..The results also suggest that practice speeds up all the mechanisms rather than adjusting their relative strengths...
  35. doi request reprint The MATRICS Consensus Cognitive Battery, part 1: test selection, reliability, and validity
    Keith H Nuechterlein
    Department of Psychology, UCLA Semel Institute for Neuroscience and Human Behavior, 300 Medical Plaza, Rm 2251, Los Angeles, CA 90095 6968, USA
    Am J Psychiatry 165:203-13. 2008
    ....
  36. doi request reprint Distinct and independent correlates of attention and awareness in a hemianopic patient
    Aaron Schurger
    Department of Psychology, Princeton University, Princeton, NJ, USA
    Neuropsychologia 46:2189-97. 2008
    ..The finding of a significant awareness-independent effect in the area of 40Hz implies that a stimulus-induced modulation of power in the canonical gamma band is not a sufficient condition for sensory awareness...
  37. doi request reprint BOLD responses reflecting dopaminergic signals in the human ventral tegmental area
    Kimberlee D'Ardenne
    Department of Chemistry, Princeton University, Princeton, NJ 08544, USA
    Science 319:1264-7. 2008
    ..When monetary gains and losses were used, VTA BOLD responses reflected positive reward prediction errors modulated by the probability of winning. We detected no significant VTA BOLD response to nonrewarding events...
  38. ncbi request reprint Theta phase resetting and the error-related negativity
    Nick Yeung
    Department of Psychology, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA
    Psychophysiology 44:39-49. 2007
    ..These findings suggest that the proposed analysis methods cannot provide unambiguous evidence that the ERN is generated by phase resetting of ongoing oscillations...
  39. ncbi request reprint Time discounting for primary rewards
    Samuel M McClure
    Center for the Study of Brain, Mind, and Behavior and Department of Psychology, Princeton University, Princeton, New Jersey 08540, USA
    J Neurosci 27:5796-804. 2007
    ..We discuss implications of this finding for differences between primary and secondary rewards...
  40. ncbi request reprint Regions of the MPFC differentially tuned to social and nonsocial affective evaluation
    Lasana T Harris
    Princeton University, Princeton, New Jersey, USA
    Cogn Affect Behav Neurosci 7:309-16. 2007
    ..Affective evaluation may be a general function of the MPFC, with some regions being tuned to more specific domains of information (e.g., social) than are others...
  41. pmc A neural network model of the Eriksen task: reduction, analysis, and data fitting
    Yuan Sophie Liu
    Department of Physics, Princeton University, Princeton, NJ 08544, USA
    Neural Comput 20:345-73. 2008
    ..We compare our results with numerical simulations of the full nonlinear model and with empirical data and show good fits to both with fewer parameters...
  42. pmc Rapid decision threshold modulation by reward rate in a neural network
    Patrick Simen
    Center for the Study of Brain, Mind and Behavior, Princeton University, Princeton, NJ 08544, USA
    Neural Netw 19:1013-26. 2006
    ..The model makes predictions regarding optimal performance and provides a benchmark against which actual performance can be compared, as well as testable predictions about the way in which reward rate may be encoded by neural mechanisms...
  43. pmc Acquisition of decision making criteria: reward rate ultimately beats accuracy
    Fuat Balci
    Princeton Neuroscience Institute, Princeton University, Green Hall, Princeton, NJ 08544, USA
    Atten Percept Psychophys 73:640-57. 2011
    ..The residual discrepancy between optimal and observed performance can be explained by an adaptive response to uncertainty in time estimation...
  44. pmc Explicit melioration by a neural diffusion model
    Patrick Simen
    Princeton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA
    Brain Res 1299:95-117. 2009
    ..Results suggest that melioration and matching may derive from synapses that estimate reward rates by a process of leaky integration, and that link together the input and output stages of a two-stage stimulus-response mechanism...
  45. ncbi request reprint Opposing BOLD responses to reciprocated and unreciprocated altruism in putative reward pathways
    James K Rilling
    Center for the Study of Brain, Mind and Behavior, Princeton University, Princeton, NJ 08544, USA
    Neuroreport 15:2539-43. 2004
    ..Our results are consistent with the hypothesis that mesencephalic dopamine projection sites carry information about errors in reward prediction that allow us to learn who can and cannot be trusted to reciprocate favors...
  46. ncbi request reprint The neural correlates of theory of mind within interpersonal interactions
    James K Rilling
    Center for the Study of Brain, Mind and Behavior, Princeton University, Princeton, NJ 08544, USA
    Neuroimage 22:1694-703. 2004
    ..Although computer partners elicited activation in some of the same areas activated by human partners, most of these activations were stronger for human partners...
  47. doi request reprint Reproducibility distinguishes conscious from nonconscious neural representations
    Aaron Schurger
    Department of Psychology, Princeton University, Princeton, NJ 08540, USA
    Science 327:97-9. 2010
    ..This is not adequately explained by a difference in signal-to-noise ratio...
  48. ncbi request reprint Dorsal anterior cingulate cortex shows fMRI response to internal and external error signals
    Clay B Holroyd
    Department of Psychology, Green Hall, Princeton University, Princeton, New Jersey 08544, USA
    Nat Neurosci 7:497-8. 2004
    ....
  49. ncbi request reprint Simplified dynamics in a model of noradrenergic modulation of cognitive performance
    Mark S Gilzenrat
    Center for the Study of Brain, Mind, and Behavior, Princeton University, NJ 08544, USA
    Neural Netw 15:647-63. 2002
    ..These results suggest a reverse sigmoidal relationship between false alarm rate and coherence, and a more complex, non-monotonic relationship between response time and coherence...
  50. ncbi request reprint Context dependence of the event-related brain potential associated with reward and punishment
    Clay B Holroyd
    Department of Psychology, Princeton University, Princeton, New Jersey 08540, USA
    Psychophysiology 41:245-53. 2004
    ..This result is discussed in terms of a recent theory that holds that the ERN reflects a reward prediction error signal associated with a neural system for reinforcement learning...
  51. ncbi request reprint Placebo-induced changes in FMRI in the anticipation and experience of pain
    Tor D Wager
    Department of Psychology, University of Michigan, 525 East University, Ann Arbor, MI 48109 1109, USA
    Science 303:1162-7. 2004
    ....
  52. pmc Reward rate optimization in two-alternative decision making: empirical tests of theoretical predictions
    Patrick Simen
    Princeton Neuroscience Institute, Princeton University, USA
    J Exp Psychol Hum Percept Perform 35:1865-97. 2009
    ..We tested the resulting quantitative predictions regarding response time, accuracy, and response bias under these task manipulations and found that grouped data conformed well to the predictions of an optimally parameterized DDM...
  53. ncbi request reprint Errors in reward prediction are reflected in the event-related brain potential
    Clay B Holroyd
    Department of Psychology, Princeton University, NJ 08544, USA
    Neuroreport 14:2481-4. 2003
    ..Consistent with the theory, we found that larger ERNs were elicited by unexpected absences of reward...
  54. pmc Optimal performance in a countermanding saccade task
    Kongfatt Wong-Lin
    Program in Applied and Computational Mathematics, Princeton University, Princeton, NJ 08544, USA
    Brain Res 1318:178-87. 2010
    ..We propose experiments to test these predictions regarding optimal behavior...
  55. ncbi request reprint The neural bases of cognitive conflict and control in moral judgment
    Joshua D Greene
    Department of Psychology, Princeton University, Princeton, NJ 08544, USA
    Neuron 44:389-400. 2004
    ..We speculate that the controversy surrounding utilitarian moral philosophy reflects an underlying tension between competing subsystems in the brain...
  56. ncbi request reprint Context-processing deficits in schizophrenia: diagnostic specificity, 4-week course, and relationships to clinical symptoms
    Deanna M Barch
    Department of Psychology, St Louis, Missouri 63130 4899, USA
    J Abnorm Psychol 112:132-43. 2003
    ..However, context-processing deficits improved in the psychotic comparison group at 4 weeks but did not improve in patients with schizophrenia...
  57. ncbi request reprint Phasic activation of monkey locus ceruleus neurons by simple decisions in a forced-choice task
    Edwin C Clayton
    Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Neurosci 24:9914-20. 2004
    ..This role of the LC in regulating the behavioral outcome of decisional processes contrasts with more traditional views of LC responses as primarily related to sensory processes...
  58. pmc Generalized signaling for control: evidence from postconflict and posterror performance adjustments
    Raymond Y Cho
    Department of Psychiatry, Western Psychiatric Institue and Clinic, University of Pittsburg, 3811 O Hara Street, Oxford 454, Pittsburg, PA 15213, USA
    J Exp Psychol Hum Percept Perform 35:1161-77. 2009
    ..The results showed that trial-to-trial adjustments exist for both direction-repeat and direction-switch trials, demonstrating that signaling for control adjustments can extend beyond the task context within which they arise...
  59. ncbi request reprint Separate neural systems value immediate and delayed monetary rewards
    Samuel M McClure
    Department of Psychology and Center for the Study of Brain, Mind, and Behavior, Princeton University, Princeton, NJ 08544, USA
    Science 306:503-7. 2004
    ..Furthermore, the relative engagement of the two systems is directly associated with subjects' choices, with greater relative fronto-parietal activity when subjects choose longer term options...
  60. ncbi request reprint Errors without conflict: implications for performance monitoring theories of anterior cingulate cortex
    Vincent van Veen
    Department of Psychology, University of Pittsburgh, PA, USA
    Brain Cogn 56:267-76. 2004
    ..These results question involvement of the ACC in the detection of errors per se when controlling for conflict...
  61. ncbi request reprint Parameterization of connectionist models
    Rafal Bogacz
    Princeton University, Princeton, New Jersey, USA
    Behav Res Methods Instrum Comput 36:732-41. 2004
    ..The method has been implemented in Matlab, is fully documented, and is available for free download from the Psychonomic Society Web archive at www.psychonomic.org/archive/...
  62. ncbi request reprint A mechanism for error detection in speeded response time tasks
    Clay B Holroyd
    Department of Psychology, Princeton University, NJ, USA
    J Exp Psychol Gen 134:163-91. 2005
    ..B. Holroyd & M. G. H. Coles, 2002). The model is used to simulate behavioral and event-related brain potential data in a speeded response time task, and the results of the simulation are compared with empirical data...
  63. pmc Prefrontal cortex and flexible cognitive control: rules without symbols
    Nicolas P Rougier
    Department of Psychology, University of Colorado, 345 UCB, Boulder, CO 80309, USA
    Proc Natl Acad Sci U S A 102:7338-43. 2005
    ..The same model is shown to apply to benchmark PFC tasks (Stroop and Wisconsin card sorting), accurately simulating the behavior of neurologically intact and frontally damaged people...
  64. ncbi request reprint Neuroeconomics: cross-currents in research on decision-making
    Alan G Sanfey
    Department of Psychology, University of Arizona, Tucson, AZ 85721, USA
    Trends Cogn Sci 10:108-16. 2006
    ..The integration of these disparate theoretical approaches and methodologies offers exciting potential for the construction of more accurate models of decision-making...
  65. ncbi request reprint Prefrontal functioning during context processing in schizophrenia and major depression: an event-related fMRI study
    Avram J Holmes
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Schizophr Res 76:199-206. 2005
    ..The imaging data replicate previous results in showing abnormal activity in the right middle frontal gyrus (BA9) in schizophrenia patients related to context processing...
  66. ncbi request reprint Neural and behavioral substrates of mood and mood regulation
    Richard J Davidson
    Department of Psychology, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    Biol Psychiatry 52:478-502. 2002
    ..Training interdisciplinary clinical scientists who meaningfully draw upon both behavioral and neuroscientific literatures and methods is critically required for the realization of these goals...
  67. ncbi request reprint The role of the locus coeruleus in mediating the attentional blink: a neurocomputational theory
    Sander Nieuwenhuis
    Department of Psychology, Princeton University, NJ, USA
    J Exp Psychol Gen 134:291-307. 2005
    ..Finally, the relationship between the authors' neurocomputational theory and existing cognitive theories of the attentional blink is discussed...
  68. ncbi request reprint Context processing in older adults: evidence for a theory relating cognitive control to neurobiology in healthy aging
    T S Braver
    Department of Psychology, Washington University, St Louis, Missouri 63130, USA
    J Exp Psychol Gen 130:746-63. 2001
    ..Older adults exhibited both performance decrements and, counterintuitively, performance improvements that are in close agreement with model predictions...
  69. ncbi request reprint Conflict monitoring versus selection-for-action in anterior cingulate cortex
    M Botvinick
    Department of Psychology, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
    Nature 402:179-81. 1999
    ....
  70. ncbi request reprint Anterior cingulate cortex, conflict monitoring, and levels of processing
    V van Veen
    Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Neuroimage 14:1302-8. 2001
    ..These results suggest a highly specific contribution of the ACC to executive functions, through the detection of conflicts occurring at later or response-related levels of processing...
  71. ncbi request reprint The physics of optimal decision making: a formal analysis of models of performance in two-alternative forced-choice tasks
    Rafal Bogacz
    Center for the Study of Brain, Mind and Behavior, Princeton University, Princeton, NJ, USA
    Psychol Rev 113:700-65. 2006
    ..They use these findings to address empirical data and make novel predictions about performance under optimality...
  72. ncbi request reprint Automatic activation of the semantic network in schizophrenia: evidence from event-related brain potentials
    Ruth Condray
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Biol Psychiatry 54:1134-48. 2003
    ....
  73. ncbi request reprint Adaptive gain and the role of the locus coeruleus-norepinephrine system in optimal performance
    Gary Aston-Jones
    Laboratory of Neuromodulation and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Comp Neurol 493:99-110. 2005
    ..We propose that these prefrontal areas produce the above patterns of LC activity to optimize the utility of performance on both short and long time scales...
  74. pmc Is knowing always feeling?
    Alan G Sanfey
    Department of Psychology, University of Arizona, Tuscon, AZ 85721, USA
    Proc Natl Acad Sci U S A 101:16709-10. 2004
  75. pmc Dynamics of attentional selection under conflict: toward a rational Bayesian account
    Angela J Yu
    Center for the Study of Brain, Mind, and Behavior, Princeton University, USA
    J Exp Psychol Hum Percept Perform 35:700-17. 2009
    ..The authors also consider how this conflict information might be disseminated and used to control processing...
  76. ncbi request reprint An integrative theory of locus coeruleus-norepinephrine function: adaptive gain and optimal performance
    Gary Aston-Jones
    Laboratory of Neuromodulation and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA
    Annu Rev Neurosci 28:403-50. 2005
    ..We propose that these frontal areas produce the above patterns of LC activity to optimize utility on both short and long timescales...
  77. ncbi request reprint Detection of synchronized oscillations in the electroencephalogram: an evaluation of methods
    Nick Yeung
    Department of Psychology, Princeton University, Princeton, New Jersey, USA
    Psychophysiology 41:822-32. 2004
    ..These findings suggest that proposed analysis methods may not effectively disambiguate competing views of ERP generation...
  78. ncbi request reprint Category-specific cortical activity precedes retrieval during memory search
    Sean M Polyn
    Department of Psychology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Science 310:1963-6. 2005
    ..This result is consistent with the hypothesis that category-specific activity is cueing the memory system to retrieve studied items...
  79. doi request reprint Functional imaging of decision conflict
    Jean Baptiste Pochon
    INSERM Avenir IFR70 and U610, Hopital Pitie Salpetriere, F 75103 Paris, France
    J Neurosci 28:3468-73. 2008
    ..Furthermore, we show that it does so for a complex decision task, one that requires the integration of beliefs and preferences and not just perceptual judgments...
  80. ncbi request reprint Prefrontal cortex dysfunction mediates deficits in working memory and prepotent responding in schizophrenia
    William M Perlstein
    Department of Clinical and Health Psychology and the McKnight Brain Institute, University of Florida, Gainesville, 32610, USA
    Biol Psychiatry 53:25-38. 2003
    ....
  81. ncbi request reprint A computational model of anterior cingulate function in speeded response tasks: effects of frequency, sequence, and conflict
    Andrew D Jones
    Washington University, St Louis, Missouri 63130, USA
    Cogn Affect Behav Neurosci 2:300-17. 2002
    ..The results indicate that the conflict-monitoring hypothesis, augmented by mechanisms for encoding stimulus history, can explain key phenomena associated with performance in sequential speeded response tasks...
  82. ncbi request reprint COMT genotype influences prefrontal response to emotional distraction
    Sonia J Bishop
    MRC Wellcome Trust Behavioural and Clinical Neuroscience Institute, Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, England
    Cogn Affect Behav Neurosci 6:62-70. 2006
    ..These findings provide an initial step toward identifying genetic contributions to interindividual variability in recruitment of mechanisms that regulate affective processing...
  83. ncbi request reprint Anterior cingulate conflict monitoring and adjustments in control
    John G Kerns
    Department of Psychological Sciences, University of Missouri Columbia, Columbia, MO 65211, USA
    Science 303:1023-6. 2004
    ....
  84. ncbi request reprint Prefrontal cortex guides context-appropriate responding during language production
    John G Kerns
    Department of Psychological Sciences, University of Missouri Columbia, 65211, USA
    Neuron 43:283-91. 2004
    ..Overall, as in other cognitive task domains, these results suggest that PFC context processing plays an important role in the control of language...
  85. pmc Cognitive load selectively interferes with utilitarian moral judgment
    Joshua D Greene
    Department of Psychology, Harvard University, 33 Kirkland St, Cambridge, MA 02138, United States
    Cognition 107:1144-54. 2008
    ..This interference effect provides direct evidence for the influence of controlled cognitive processes in moral judgment, and utilitarian moral judgment more specifically...
  86. ncbi request reprint Computational roles for dopamine in behavioural control
    P Read Montague
    Department of Neuroscience, Baylor College of Medicine, 1 Baylor Plaza, Houston, Texas 77030, USA
    Nature 431:760-7. 2004
    ..The application of such quantitative models has opened up new fields, ripe for attack by young synthesizers and theoreticians...
  87. ncbi request reprint Conflict monitoring and anterior cingulate cortex: an update
    Matthew M Botvinick
    University of Pennsylvania, Center for Cognitive Neuroscience, 3720 Walnut Street, Philadelphia, PA 10104 6241, USA
    Trends Cogn Sci 8:539-46. 2004
    ..Recent research has also begun to shed light on the larger function of the ACC, suggesting some new possibilities concerning how conflict monitoring might fit into the cingulate's overall role in cognition and action...
  88. ncbi request reprint Altering expectancy dampens neural response to aversive taste in primary taste cortex
    Jack B Nitschke
    Waisman Laboratory for Brain Imaging and Behavior, Waisman Center, Departments of Psychiatry and Psychology, University of Wisconsin, 1500 Highland Avenue, Madison, Wisconsin 53705 2274, USA
    Nat Neurosci 9:435-42. 2006
    ..In addition, the activation of the right insula and operculum tracked online ratings of the aversiveness for each taste. Such expectancy-driven modulation of primary sensory cortex may affect perceptions of external events...
  89. ncbi request reprint Dissociating affective evaluation and social cognitive processes in the ventral medial prefrontal cortex
    Wouter van den Bos
    University of Amsterdam, Amsterdam, The Netherlands
    Cogn Affect Behav Neurosci 7:337-46. 2007
    ..These findings suggest that, within the vmPFC, the PACC subserves primarily an affective function, whereas in other regions social context can modulate affective responses...
  90. ncbi request reprint Factors influencing Stroop performance in schizophrenia
    Deanna M Barch
    Washington University, St Louis, MO 63130, USA
    Neuropsychology 18:477-84. 2004
    ....
  91. ncbi request reprint Cognitive neuroscience: decision amid uncertainty
    Jonathan D Cohen
    Nature 436:471-2. 2005
  92. ncbi request reprint Decreased conflict- and error-related activity in the anterior cingulate cortex in subjects with schizophrenia
    John G Kerns
    UC Davis Imaging Research Center, University of California Davis, 4701 X Street, Sacramento, CA 95817, USA
    Am J Psychiatry 162:1833-9. 2005
    ..This study examined whether impaired conflict monitoring in people with schizophrenia could underlie reduced anterior cingulate activity during both correct task performance and error-related activity...
  93. ncbi request reprint Neuroeconomics
    George Loewenstein
    Department of Social and Decision Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
    Annu Rev Psychol 59:647-72. 2008
    ..In addition to reviewing new economic models inspired by this research, we also discuss how neuroeconomics may influence future work in psychology...

Research Grants27

  1. Functional MRI and Modeling Studies of Prefrontal Cortex
    Jonathan Cohen; Fiscal Year: 2007
    ..abstract_text> ..
  2. Cognitive and Neural Mechanisms of Decision and Control
    Jonathan Cohen; Fiscal Year: 2007
    ....
  3. Neural mechanisms and social influence in delay discounting and impulsive choice
    Jonathan Cohen; Fiscal Year: 2007
    ....
  4. Mechanisms of Context Processing in Schizophrenia
    Jonathan Cohen; Fiscal Year: 2009
    ....
  5. NRSA Training Grant in Quantitative Neuroscience
    Jonathan Cohen; Fiscal Year: 2006
    ....
  6. FUNCTIONAL MRI STUDIES OF PREFRONTAL CORTEX
    Jonathan Cohen; Fiscal Year: 1999
    ..A better understanding of PFC promises to provide important insights into the mechanisms underlying uniquely human cognitive abilities, such as problem solving and language, and their disturbance in diseases such as schizophrenia. ..
  7. MECHANISM OF CONTEXT PROCESSING IN SCHIZOPHRENIA
    Jonathan Cohen; Fiscal Year: 2001
    ....
  8. USABILITY AND INTEROPERABILITY OF NEUROIMAGING SOFTWARE
    Jonathan Cohen; Fiscal Year: 2002
    ..This Desktop will be written in Java and will use CORBA to manage the client/server interactions. ..
  9. Neural mechanisms and social influence in delay discounting and impulsive choice
    Jonathan D Cohen; Fiscal Year: 2010
    ....