Jannette Carey

Summary

Affiliation: Princeton University
Country: USA

Publications

  1. pmc Environment-dependent long-range structural distortion in a temperature-sensitive point mutant
    Jannette Carey
    Chemistry Department, Princeton University, Princeton, New Jersey 08544, USA
    Protein Sci 21:63-74. 2012
  2. pmc Protein reconstitution and three-dimensional domain swapping: benefits and constraints of covalency
    Jannette Carey
    Chemistry Department, Princeton University, NJ 08544 1009, USA
    Protein Sci 16:2317-33. 2007
  3. pmc WrbA bridges bacterial flavodoxins and eukaryotic NAD(P)H:quinone oxidoreductases
    Jannette Carey
    Chemistry Department, Princeton University, Princeton, New Jersey 08544 1009, USA
    Protein Sci 16:2301-5. 2007
  4. doi request reprint Synergy of molecular dynamics and isothermal titration calorimetry in studies of allostery
    Rebecca Strawn
    Chemistry Department, Princeton University, Princeton, New Jersey, USA
    Methods Enzymol 492:151-88. 2011
  5. pmc Symmetric allosteric mechanism of hexameric Escherichia coli arginine repressor exploits competition between L-arginine ligands and resident arginine residues
    Rebecca Strawn
    Chemistry Department, Princeton University, Princeton, New Jersey, USA
    PLoS Comput Biol 6:e1000801. 2010
  6. pmc Calmodulin transduces Ca2+ oscillations into differential regulation of its target proteins
    Nikolai Slavov
    Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA
    ACS Chem Neurosci 4:601-12. 2013
  7. ncbi request reprint Asymmetric allosteric activation of the symmetric ArgR hexamer
    Lihua Jin
    Chemistry Department, DePaul University, Chicago, IL 60614, USA
    J Mol Biol 346:43-56. 2005
  8. pmc Crystallization and preliminary diffraction analysis of Escherichia coli WrbA in complex with its cofactor flavin mononucleotide
    Julie Wolfova
    Institute of Physical Biology, University of South Bohemia Ceske Budejovice, Zamek 136, CZ 373 33 Nove Hrady, Czech Republic
    Acta Crystallogr Sect F Struct Biol Cryst Commun 63:571-5. 2007
  9. ncbi request reprint Role of flavin mononucleotide in the thermostability and oligomerization of Escherichia coli stress-defense protein WrbA
    Antonino Natalello
    Department of Biotechnology and Biosciences, University of Milano Bicocca, Milan, Italy
    Biochemistry 46:543-53. 2007
  10. ncbi request reprint Spectroelectrochemical investigation of a flavoprotein with a flavin-modified gold electrode
    Gilbert Nöll
    Institut fur Organische Chemie, Universitat Regensburg, Universitatsstrasse 31, D 93051 Regensburg, Germany
    Langmuir 22:2378-83. 2006

Research Grants

  1. BIAcore 3000 System
    Jannette Carey; Fiscal Year: 2005

Collaborators

Detail Information

Publications15

  1. pmc Environment-dependent long-range structural distortion in a temperature-sensitive point mutant
    Jannette Carey
    Chemistry Department, Princeton University, Princeton, New Jersey 08544, USA
    Protein Sci 21:63-74. 2012
    ....
  2. pmc Protein reconstitution and three-dimensional domain swapping: benefits and constraints of covalency
    Jannette Carey
    Chemistry Department, Princeton University, NJ 08544 1009, USA
    Protein Sci 16:2317-33. 2007
    ..The results imply that noncovalent interactions in a protein are sufficient to specify its structure under the constraints imposed by the covalent backbone...
  3. pmc WrbA bridges bacterial flavodoxins and eukaryotic NAD(P)H:quinone oxidoreductases
    Jannette Carey
    Chemistry Department, Princeton University, Princeton, New Jersey 08544 1009, USA
    Protein Sci 16:2301-5. 2007
    ..The structure suggests a novel physiological role for WrbA and Nqo1...
  4. doi request reprint Synergy of molecular dynamics and isothermal titration calorimetry in studies of allostery
    Rebecca Strawn
    Chemistry Department, Princeton University, Princeton, New Jersey, USA
    Methods Enzymol 492:151-88. 2011
    ..In this synergistic approach molecular dynamics forms an integral part of a feedback loop of hypothesis, experimental design, and interpretation that conforms to the scientific method...
  5. pmc Symmetric allosteric mechanism of hexameric Escherichia coli arginine repressor exploits competition between L-arginine ligands and resident arginine residues
    Rebecca Strawn
    Chemistry Department, Princeton University, Princeton, New Jersey, USA
    PLoS Comput Biol 6:e1000801. 2010
    ....
  6. pmc Calmodulin transduces Ca2+ oscillations into differential regulation of its target proteins
    Nikolai Slavov
    Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA
    ACS Chem Neurosci 4:601-12. 2013
    ..The results rationalize calmodulin signaling in terms of the network topology and the molecular properties of calmodulin...
  7. ncbi request reprint Asymmetric allosteric activation of the symmetric ArgR hexamer
    Lihua Jin
    Chemistry Department, DePaul University, Chicago, IL 60614, USA
    J Mol Biol 346:43-56. 2005
    ..The analysis suggests a novel thermodynamic signature for this mechanism of activation...
  8. pmc Crystallization and preliminary diffraction analysis of Escherichia coli WrbA in complex with its cofactor flavin mononucleotide
    Julie Wolfova
    Institute of Physical Biology, University of South Bohemia Ceske Budejovice, Zamek 136, CZ 373 33 Nove Hrady, Czech Republic
    Acta Crystallogr Sect F Struct Biol Cryst Commun 63:571-5. 2007
    ..X-ray crystal structures of the WrbA holoprotein have been determined to resolutions of 2.0 and 2.6 A...
  9. ncbi request reprint Role of flavin mononucleotide in the thermostability and oligomerization of Escherichia coli stress-defense protein WrbA
    Antonino Natalello
    Department of Biotechnology and Biosciences, University of Milano Bicocca, Milan, Italy
    Biochemistry 46:543-53. 2007
    ..This study illustrates the utility of analyzing conformational transitions and intermolecular interactions using methods that probe the liquid, solid, and gas phases...
  10. ncbi request reprint Spectroelectrochemical investigation of a flavoprotein with a flavin-modified gold electrode
    Gilbert Nöll
    Institut fur Organische Chemie, Universitat Regensburg, Universitatsstrasse 31, D 93051 Regensburg, Germany
    Langmuir 22:2378-83. 2006
    ..The presented electrode surface modification may generally lend itself for spectroelectrochemical investigations of flavoproteins...
  11. ncbi request reprint Biophysical properties of regions flanking the bHLH-Zip motif in the p22 Max protein
    Sharon E Pursglove
    Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77 Stockholm, Sweden
    Biochem Biophys Res Commun 323:750-9. 2004
    ..Thus, the previously observed functionalities of these Max regions in DNA binding, phosphorylation, and apoptosis are suggested to be linked to structural properties...
  12. pmc E. coli trp repressor forms a domain-swapped array in aqueous alcohol
    Catherine L Lawson
    Rutgers University, Department of Chemistry and Chemical Biology, 610 Taylor Road, Piscataway, NJ 08854, USA
    Structure 12:1099-108. 2004
    ..Small angle X-ray scattering measurements show that the self-association properties of trpR in solution are fundamentally altered by isopropanol...
  13. ncbi request reprint Assembly of the hexameric Escherichia coli arginine repressor investigated by nano-electrospray ionization time-of-flight mass spectrometry
    Maria Samalikova
    Institute of Organic Chemistry, Johannes Kepler University, Altenbergerstrasse 69, 4040 Linz, Austria
    Rapid Commun Mass Spectrom 19:2549-52. 2005
    ..The observed species distributions suggest a role for the N-terminal domain in hexamer stabilization...
  14. ncbi request reprint Multi-method global analysis of thermodynamics and kinetics in reconstitution of monellin
    Wei Feng Xue
    Department of Biophysical Chemistry, Lund University, Lund, Sweden
    Proteins 57:586-95. 2004
    ..8 J mol(-1) K(-1) (-TDeltaS degrees = -23.8 kJ/mol). The association of monellin is therefore a bimolecular intra-protein association whose energetics are slightly dominated by entropic factors...
  15. ncbi request reprint Three-dimensional solution NMR structure of Apo-L75F-TrpR, a temperature-sensitive mutant of the tryptophan repressor protein
    Robert Tyler
    Department of Chemistry and Biochemistry, Montana State University, 108 Gaines Hall, Bozeman, MT 59717, USA
    Biochemistry 41:11954-62. 2002
    ..The data provide evidence that this point mutation exerts local effects on structure and stability in the DNA binding domain, and propagates long-range effects through the tertiary structure...

Research Grants1

  1. BIAcore 3000 System
    Jannette Carey; Fiscal Year: 2005
    ..The instrument will also support instruction in the fundamental principles and practice of ligand-binding analysis for graduate and advanced undergraduate students. ..