Research Topics
| Tony G BabbSummaryAffiliation: Presbyterian Hospital of Dallas Country: USA Publications
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Detail Information
Publications
Weight loss via diet and exercise improves exercise breathing mechanics in obese menTony G Babb
Institute for Exercise and Environmental Medicine, Dallas, TX 75231, USA
Chest 140:454-60. 2011..We hypothesized that weight loss, especially a decrease in abdominal fat, would improve breathing mechanics during exercise because of an increase in end-expiratory lung volume (EELV)...
Fat distribution and end-expiratory lung volume in lean and obese men and womenTony G Babb
Institute for Exercise and Environmental Medicine, University of Texas Southwestern Medical Center Presbyterian Hospital of Dallas, Dallas, TX, USA
Chest 134:704-11. 2008....
Dyspnea on exertion in obese women: association with an increased oxygen cost of breathingTony G Babb
Institute for Exercise and Environmental Medicine, 7232 Greenville Avenue, Dallas, TX 75231, USA
Am J Respir Crit Care Med 178:116-23. 2008..Although exertional dyspnea in obesity is an important and prolific clinical concern, the underlying mechanism remains unclear...
Short- and long-term modulation of the exercise ventilatory responseTony G Babb
Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, 7232 Greenville Ave, Dallas, TX 75231, USA
Med Sci Sports Exerc 42:1681-7. 2010..Short-term modulation is proposed to be an important regulatory mechanism that helps maintain blood gas homeostasis during exercise...
Ventilatory response to exercise in aged runners breathing He-O2 or inspired CO2T G Babb
Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas and The University of Texas Southwestern Medical Center, 77231, USA
J Appl Physiol 94:685-93. 2003....
Hyperventilation with He-O2 breathing is not decreased by superimposed external resistanceT G Babb
Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas and The University of Texas Southwestern Medical Center, 7232 Greenville Avenue, Dallas, TX 77231, USA
Respir Physiol Neurobiol 133:139-51. 2002..In conclusion, these data suggest that inspiratory resistive unloading is no more important than expiratory resistive unloading to the increase in VE with He-O(2) breathing during heavy and peak exercise...
Mild obesity does not limit change in end-expiratory lung volume during cycling in young womenT G Babb
Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas and The University of Texas Southwestern Medical Center, Dallas, Texas 77231, USA
J Appl Physiol 92:2483-90. 2002..Also, these data suggest that other nonmechanical factors also regulate the level of EELV during exercise...
Breathing He-O2 increases ventilation but does not decrease the work of breathing during exerciseT G Babb
Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas, and University of Texas Southwestern Medical Center, Dallas, Texas, USA
Am J Respir Crit Care Med 163:1128-34. 2001..We concluded that V E is increased during He-O2 breathing because of resistive unloading of the airways and the maintenance of the relationship between the work of breathing and exercise work rate...
The ventilatory response to exercise does not differ between obese women with and without dyspnea on exertionHelen E Wood
Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas, and UT Southwestern Medical Center, USA
Adv Exp Med Biol 605:514-8. 2008
Oxygen cost of breathing and breathlessness during exercise in nonobese women and menSantiago Lorenzo
Institute for Exercise and Environmental Medicine, Texas Health Pregbyterian Hospital Dallas and The University of Texas Southwestern Medical Center, Dallas, TX 75231, USA
Med Sci Sports Exerc 44:1043-8. 2012..Also, the association between the oxygen cost of breathing and rating of perceived breathlessness (RPB) during exercise has not been examined between women and men...
Short-term modulation of the exercise ventilatory response in younger and older womenHelen E Wood
Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, TX 75231, United States
Respir Physiol Neurobiol 179:235-47. 2011..EVR with and without added DS did not differ between age groups. We conclude that the capacity for STM of the EVR with added DS is similar in healthy younger and older women...
Short-term modulation of the exercise ventilatory response in older menHelen E Wood
Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, and University of Texas Southwestern Medical Center Dallas, 7232 Greenville Ave, Dallas, TX 75231, United States
Respir Physiol Neurobiol 173:37-46. 2010....
Mild-to-moderate obesity: implications for respiratory mechanics at rest and during exercise in young menD S DeLorey
Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas, TX 75231, USA
Int J Obes (Lond) 29:1039-47. 2005..During moderate exercise, obesity does not appear to limit changes in EELV; however, the regulation of EELV during heavy exercise appears to be affected...
The importance of the muscle and ventilatory blood pumps during exercise in patients without a subpulmonary ventricle (Fontan operation)Keri M Shafer
Department of Internal Medicine, University of Texas Southwestern, Dallas, TX, USA
J Am Coll Cardiol 60:2115-21. 2012..The aim of this study was to determine the relative contribution of the muscle and ventilatory pumps to stroke volume in patients without a subpulmonic ventricle...
Accuracy of estimating resting oxygen uptake and implications for hemodynamic assessmentNikhil Narang
Department of Internal Medicine, Texas Health Presbyterian Hospital, University of Texas Southwestern Medical School, Dallas, USA
Am J Cardiol 109:594-8. 2012..Estimation of VO(2) at rest is inaccurate, especially in men and with increasing adiposity. In conclusion, when clinical hemodynamic assessment is performed, VO(2) should be measured, not estimated...
Short-term modulation of the exercise ventilatory response in young menHelen E Wood
Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas, and University of Texas Southwestern Medical Center Dallas, Dallas, Texas 75231, USA
J Appl Physiol 104:244-52. 2008..We conclude that STM of the exercise ventilatory response is induced in young men when resting ventilatory drive is increased with external DS, confirming the existence of STM in humans...
Ventilatory responses to exercise and hypercapnia following 18 days of head-down restHelen E Wood
Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas, University of Texas Southwestern Medical Center Dallas, Dallas, TX 75231, USA
Aviat Space Environ Med 80:395-9. 2009..Based on limited previous studies, we hypothesized that the ventilatory response to exercise would be increased, while the HCVR would be decreased after HDR...
Breathing mechanics during exercise with added dead space reflect mechanisms of ventilatory controlHelen E Wood
Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, University of Texas Southwestern Medical Center Dallas, 7232 Greenville Ave, Dallas, TX 75231, USA
Respir Physiol Neurobiol 168:210-7. 2009..Hence, we conclude that fundamental differences exist in the neural control of ventilatory responses during exercise, increased V(D) and STM...
Quantification of cardiorespiratory fitness in healthy nonobese and obese men and womenSantiago Lorenzo
Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, TX 75231
Chest 141:1031-9. 2012..We retrospectively compared peak oxygen uptake (VO(2)peak) (ie, CRF) in absolute terms, and relative terms (% predicted) using three currently suggested prediction equations (Equations R, W, and G)...
Exertional dyspnea in mitochondrial myopathy: clinical features and physiological mechanismsKatja Heinicke
Neuromuscular Center, Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, 7232 Greenville Ave, 435, Dallas, TX 75231 5129, USA
Am J Physiol Regul Integr Comp Physiol 301:R873-84. 2011....
Obesity: associations with acute mountain sicknessGe Ri-Li
Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas, Texas 75231, USA
Ann Intern Med 139:253-7. 2003..CONCLUSION: Obesity seems to be associated with the development of AMS, which may be partly related to greater nocturnal desaturation with altitude exposure...
Ventilation and respiratory mechanics during exercise in younger subjects breathing CO2 or HeO2T G Babb
Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas, TX, USA
Respir Physiol 109:15-28. 1997..This suggests that in younger subjects with normal lung function there are minimal mechanical ventilatory constraints on VE during maximal exercise...
Mechanical ventilatory constraints in aging, lung disease, and obesity: perspectives and brief reviewT G Babb
Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas, TX 75231
Med Sci Sports Exerc 31:S12-22. 1999....
Corrected end-tidal P(CO(2)) accurately estimates Pa(CO(2)) at rest and during exercise in morbidly obese adultsVipa Bernhardt
Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas and University of Texas Southwestern Medical Center, Dallas, TX 75231, USA
Chest 143:471-7. 2013..5 + 0.9 x P(ETCO(2)) – 2.1 x tidal volume). The purpose of this project was to determine the accuracy of Pa(CO(2)) estimations from P(ETCO(2)) and P(JCO(2)) values at rest and at submaximal and peak exercise in morbidly obese adults...
Mechanism of reduced maximal expiratory flow with agingT G Babb
Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas, and University of Texas Southwestern Medical Center, 77231, USA
J Appl Physiol 89:505-11. 2000..These data indicate that the loss of lung recoil explains the decrease in MEF with aging subjects, but not in the mild CAL patients that we studied...
Dyspnea on exertion in obese menVipa Bernhardt
Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas and University of Texas Southwestern Medical Center, 7232 Greenville Ave, Ste 435, Dallas, TX 75231, USA
Respir Physiol Neurobiol 185:241-8. 2013..The mechanism of dyspnea on exertion in obese men seems unrelated to the oxygen cost of breathing...
The confounding effects of thoracic gas compression on measurement of acute bronchodilator responseAmir Sharafkhaneh
Baylor College of Medicine, MED VAMC, Bldg 100 111i, Houston, TX 77030, USA
Am J Respir Crit Care Med 175:330-5. 2007..Improvement in FEV(1) is a main endpoint in clinical trials assessing the efficacy of bronchodilators. However, the effect of bronchodilators on maximal expiratory flow may be confounded by thoracic gas compression (TGC)...
Layers of exercise hyperpnea: modulation and plasticityGordon S Mitchell
Department of Comparative Biosciences, University of Wisconsin, 2015 Linden Drive, Madison, WI 53706, USA
Respir Physiol Neurobiol 151:251-66. 2006..g. development, aging, onset of disease) or exogenous (e.g. altitude, wearing a breathing apparatus during physical exertion) physiological conditions...
