Jocelyn H Wright

Summary

Affiliation: Preclinical Research and Exploratory Development
Country: USA

Publications

  1. ncbi Mitogen-activated protein kinase kinase activity is required for the G(2)/M transition of the cell cycle in mammalian fibroblasts
    J H Wright
    Department of Pharmacology, University of Washington, Seattle, WA 98103, USA
    Proc Natl Acad Sci U S A 96:11335-40. 1999
  2. ncbi The STE20 kinase HGK is broadly expressed in human tumor cells and can modulate cellular transformation, invasion, and adhesion
    Jocelyn H Wright
    SUGEN, Inc, South San Francisco, California 94080, USA
    Mol Cell Biol 23:2068-82. 2003
  3. ncbi Defective DNA strand break repair causes chromosomal instability and accelerates liver carcinogenesis in mice
    Narci C Teoh
    Australian National University Medical School, Canberra, Australia
    Hepatology 47:2078-88. 2008

Collaborators

Detail Information

Publications3

  1. ncbi Mitogen-activated protein kinase kinase activity is required for the G(2)/M transition of the cell cycle in mammalian fibroblasts
    J H Wright
    Department of Pharmacology, University of Washington, Seattle, WA 98103, USA
    Proc Natl Acad Sci U S A 96:11335-40. 1999
    ..These data demonstrate a novel role for the MAPK cascade in progression from G(2) into mitosis in NIH 3T3 cells...
  2. ncbi The STE20 kinase HGK is broadly expressed in human tumor cells and can modulate cellular transformation, invasion, and adhesion
    Jocelyn H Wright
    SUGEN, Inc, South San Francisco, California 94080, USA
    Mol Cell Biol 23:2068-82. 2003
    ..Together, these results suggest an important role for HGK in cell transformation and invasiveness...
  3. ncbi Defective DNA strand break repair causes chromosomal instability and accelerates liver carcinogenesis in mice
    Narci C Teoh
    Australian National University Medical School, Canberra, Australia
    Hepatology 47:2078-88. 2008
    ..CONCLUSION: These findings demonstrate that defects in the NHEJ DNA repair pathway may participate in the disruption of cell cycle checkpoints leading to chromosomal instability and accelerated development of HCC...