Jui Yi Tsai

Summary

Affiliation: PPG Industries
Country: USA

Publications

  1. ncbi request reprint The search for gamma-secretase and development of inhibitors
    Jui Yi Tsai
    PPG Industrial, 440 College Park Drive, Monroeville, PA 15146, USA
    Curr Med Chem 9:1087-106. 2002
  2. ncbi request reprint Designed helical peptides inhibit an intramembrane protease
    Chittaranjan Das
    Center for Neurologic Diseases, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Chem Soc 125:11794-5. 2003

Collaborators

Detail Information

Publications2

  1. ncbi request reprint The search for gamma-secretase and development of inhibitors
    Jui Yi Tsai
    PPG Industrial, 440 College Park Drive, Monroeville, PA 15146, USA
    Curr Med Chem 9:1087-106. 2002
    ..In this article, we review the current knowledge of gamma-secretase biochemistry and cell biology and the development of inhibitors of this important therapeutic target...
  2. ncbi request reprint Designed helical peptides inhibit an intramembrane protease
    Chittaranjan Das
    Center for Neurologic Diseases, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Chem Soc 125:11794-5. 2003
    ..These findings are consistent with helical peptides interacting with the initial substrate docking site of gamma-secretase, suggesting a general strategy for the development of potent and specific inhibitors of intramembrane proteases...