Research Topics
Species | Suzanne EstesSummaryAffiliation: Portland State University Country: USA Publications
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Detail Information
Publications
Behavioral degradation under mutation accumulation in Caenorhabditis elegansBeverly C Ajie
Center for Ecology and Evolutionary Biology, University of Oregon, Eugene, 97503-5289, USA
Genetics 170:655-60. 2005..These results have important implications for the maintenance of genetic variation for behavior in natural populations as well as for expectations for behavioral change within endangered species and captive populations...
Variation in pleiotropy and the mutational underpinnings of the G-matrixSuzanne Estes
Department of Biology, Portland State University, Portland, Oregon 97201, USA
Evolution 60:2655-60. 2006..e., small-effect mutations reduce the magnitude of covariation between characters), but do not change the direction of this covariation...
Fitness recovery and compensatory evolution in natural mutant lines of C. elegansSuzanne Estes
Department of Biology, Portland State University, Portland, Oregon 97201, USA
Evolution 65:2335-44. 2011....
Natural variation in life history and aging phenotypes is associated with mitochondrial DNA deletion frequency in Caenorhabditis briggsaeSuzanne Estes
Department of Biology, Portland State University, Portland, OR 97201, USA
BMC Evol Biol 11:11. 2011..The normal product of ND5 is a central component of the mitochondrial electron transport chain and integral to cellular energy metabolism...
Resolving the paradox of stasis: models with stabilizing selection explain evolutionary divergence on all timescalesSuzanne Estes
Department of Zoology, Oregon State University, Corvallis, Oregon 97331, USA
Am Nat 169:227-44. 2007..We discuss the implication of our results for comparative studies and phylogeny inference based on phenotypic characters...
Selfish little circles: transmission bias and evolution of large deletion-bearing mitochondrial DNA in Caenorhabditis briggsae nematodesKatie A Clark
Department of Zoology and Center for Genome Research and Biocomputing, Oregon State University, Corvallis, Oregon, United States of America
PLoS ONE 7:e41433. 2012..briggsae, offering a powerful new system to study selfish mtDNA dynamics in metazoans...
In vivo quantification reveals extensive natural variation in mitochondrial form and function in Caenorhabditis briggsaeKiley A Hicks
Biology Department, Portland State University, Portland, Oregon, United States of America
PLoS ONE 7:e43837. 2012..This study demonstrates that multicellular eukaryotic species are capable of extensive natural variation in organellar phenotypes and highlights the potential of integrating evolutionary and cell biology perspectives...
Mutation rates, spectra and hotspots in mismatch repair-deficient Caenorhabditis elegansDee R Denver
Department of Biology, Indiana University, Bloomington, 47405, USA
Genetics 170:107-13. 2005..elegans MA lines. This, along with the apparent absence of a Saccharomyces cerevisiae MSH3 ortholog in the C. elegans genome, suggests that C. elegans MMR surveillance is carried out by a single Msh-2/Msh-6 heterodimer...
Selective sweeps and parallel mutation in the adaptive recovery from deleterious mutation in Caenorhabditis elegansDee R Denver
Department of Zoology, Oregon State University, Corvallis, Oregon 97331, USA
Genome Res 20:1663-71. 2010..Our study suggests that recovery-line mutations identified in both coding and noncoding genomic regions might have beneficial effects associated with compensatory epistatic interactions...
Natural variation in Caenorhabditis briggsae mitochondrial form and function suggests a novel model of organelle dynamicsKiley A Hicks
Biology Department, Portland State University, 1719 SW 10th Ave, Portland, OR 97201, USA Electronic address
Mitochondrion 13:44-51. 2013..Further, our study suggests a novel model of mitochondrial population dynamics dependent upon cellular environmental context and with implications for mitochondrial genome integrity...
Spontaneous mutational correlations for life-history, morphological and behavioral characters in Caenorhabditis elegansSuzanne Estes
Center for Ecology and Evolutionary Biology, University of Oregon, Eugene, 97403, USA
Genetics 170:645-53. 2005..Observed mutational correlations are shown to be higher than those produced by the chance accumulation of nonpleiotropic mutations in the same lines...
Abundance, distribution, and mutation rates of homopolymeric nucleotide runs in the genome of Caenorhabditis elegansDee R Denver
Department of Biology, Indiana University, 327 Jordan Hall, 1001 East Third Street, 47405, Bloomington, IN, USA
J Mol Evol 58:584-95. 2004..This integrative approach yields a total nuclear genome-wide homopolymer mutation rate estimate of approximately 1.6 mutations per genome per generation...
Mutation accumulation in populations of varying size: the distribution of mutational effects for fitness correlates in Caenorhabditis elegansSuzanne Estes
Center for Ecology and Evolutionary Biology, University of Oregon, Eugene, Oregon 97403, USA
Genetics 166:1269-79. 2004....
Rapid fitness recovery in mutationally degraded lines of Caenorhabditis elegansSuzanne Estes
Department of Biology, University of Oregon, Eugene, Oregon 97403, USA
Evolution 57:1022-30. 2003..This surprising result has broad implications for the influence of the mutational process on many issues in evolutionary and conservation biology...
