D M Phillips

Summary

Affiliation: Population Council
Country: USA

Publications

  1. ncbi request reprint Nonoxynol-9 enhances rectal infection by herpes simplex virus in mice
    D M Phillips
    Contraception 57:341-8. 1998
  2. ncbi request reprint Ultrastructure of the murine cervix following infection with Chlamydia trachomatis
    D M Phillips
    Population Council, New York, NY 10021, USA
    Tissue Cell 30:446-52. 1998
  3. ncbi request reprint Nonoxynol-9 causes rapid exfoliation of sheets of rectal epithelium
    D M Phillips
    The Population Council, 1230 York Ave, New York, NY 10021, USA
    Contraception 62:149-54. 2000
  4. ncbi request reprint Lubricants containing N-9 may enhance rectal transmission of HIV and other STIs
    David M Phillips
    Population Council, 1230 York Avenue, New York, NY 10021, USA
    Contraception 70:107-10. 2004
  5. ncbi request reprint Comparison of microbicides for efficacy in protecting mice against vaginal challenge with herpes simplex virus type 2, cytotoxicity, antibacterial properties, and sperm immobilization
    R A Maguire
    Population Council, New York, New York 10021, USA
    Sex Transm Dis 28:259-65. 2001
  6. ncbi request reprint Pushing the frontiers of science--the Population Council's Microbicide Basic Science Network on vaginal microbicide research
    E D Johansson
    The Population Council, New York, NY, USA
    Int J Gynaecol Obstet 67:S117-24. 1999
  7. ncbi request reprint Unusual ampullary sperm crypts, and behavior and role of the cumulus oophorus, in the oviduct of the least shrew, Cryptotis parva
    J M Bedford
    Department of Obstetrics and Gynecology, Cornell University Medical College, New York, New York 10021, USA
    Biol Reprod 56:1255-67. 1997
  8. ncbi request reprint Factors that may regulate assembly of the mammalian sperm tail deduced from a mouse t complex mutation
    D M Phillips
    Population Council, New York, New York 10021
    Biol Reprod 49:1347-52. 1993
  9. ncbi request reprint Relative safety of sexual lubricants for rectal intercourse
    Kristin M Sudol
    Population Council, New York, New York, USA
    Sex Transm Dis 31:346-9. 2004
  10. ncbi request reprint Human genital epithelial cells capture cell-free human immunodeficiency virus type 1 and transmit the virus to CD4+ Cells: implications for mechanisms of sexual transmission
    Zhiwei Wu
    Department of Biochemistry, School of Dental Medicine, University of Pennsylvania, Philadelphia 19104, USA
    J Infect Dis 188:1473-82. 2003

Research Grants

Collaborators

  • C L Taylor
  • J M Bedford
  • Kristin M Sudol
  • Jose A Fern├índez-Romero
  • Mitchell Thorn
  • R A Maguire
  • Robin A Maguire
  • Andrea Wallace
  • Zhiwei Wu
  • E D Johansson
  • Kristin Sudol
  • Kanani Titchen
  • Stuart G Turville
  • Jifan Li
  • Robert W Buckheit
  • Tracy L Hartman
  • Todd Miller
  • Melissa Robbiani
  • Zhiwei Chen
  • N Bergman

Detail Information

Publications12

  1. ncbi request reprint Nonoxynol-9 enhances rectal infection by herpes simplex virus in mice
    D M Phillips
    Contraception 57:341-8. 1998
    ..These findings suggest that use of N9-containing products during rectal intercourse may increase the risk of infection with HSV-2 or other sexually transmitted pathogens...
  2. ncbi request reprint Ultrastructure of the murine cervix following infection with Chlamydia trachomatis
    D M Phillips
    Population Council, New York, NY 10021, USA
    Tissue Cell 30:446-52. 1998
    ..Our observations also suggest that persistent chlamydia can form in some of the cells of the cervical epithelium that are infected by the initial inoculation...
  3. ncbi request reprint Nonoxynol-9 causes rapid exfoliation of sheets of rectal epithelium
    D M Phillips
    The Population Council, 1230 York Ave, New York, NY 10021, USA
    Contraception 62:149-54. 2000
    ..We, therefore, caution against the use of N-9-containing products during rectal intercourse...
  4. ncbi request reprint Lubricants containing N-9 may enhance rectal transmission of HIV and other STIs
    David M Phillips
    Population Council, 1230 York Avenue, New York, NY 10021, USA
    Contraception 70:107-10. 2004
    ..Because the rectal epithelium protects target cells in the submucosa from HIV, we conclude that lubricants containing N-9 should be avoided during rectal sex...
  5. ncbi request reprint Comparison of microbicides for efficacy in protecting mice against vaginal challenge with herpes simplex virus type 2, cytotoxicity, antibacterial properties, and sperm immobilization
    R A Maguire
    Population Council, New York, New York 10021, USA
    Sex Transm Dis 28:259-65. 2001
    ..CONCLUSION: Evaluating formulations under the same testing conditions can help to distinguish among potential formulations that are likely to show promise as safe and effective microbicides...
  6. ncbi request reprint Pushing the frontiers of science--the Population Council's Microbicide Basic Science Network on vaginal microbicide research
    E D Johansson
    The Population Council, New York, NY, USA
    Int J Gynaecol Obstet 67:S117-24. 1999
    ....
  7. ncbi request reprint Unusual ampullary sperm crypts, and behavior and role of the cumulus oophorus, in the oviduct of the least shrew, Cryptotis parva
    J M Bedford
    Department of Obstetrics and Gynecology, Cornell University Medical College, New York, New York 10021, USA
    Biol Reprod 56:1255-67. 1997
    ..This and related evidence from other shrews makes it seem likely that the soricid cumulus has an essential role in fertilization and may induce the acrosome reaction...
  8. ncbi request reprint Factors that may regulate assembly of the mammalian sperm tail deduced from a mouse t complex mutation
    D M Phillips
    Population Council, New York, New York 10021
    Biol Reprod 49:1347-52. 1993
    ..In addition, while dense fibers can form normally in association with singlet microtubules, the fibrous sheath requires the axoneme as a substrate for normal organization...
  9. ncbi request reprint Relative safety of sexual lubricants for rectal intercourse
    Kristin M Sudol
    Population Council, New York, New York, USA
    Sex Transm Dis 31:346-9. 2004
    ..The current study was conducted to determine the relative safety of sexual lubricants for rectal use...
  10. ncbi request reprint Human genital epithelial cells capture cell-free human immunodeficiency virus type 1 and transmit the virus to CD4+ Cells: implications for mechanisms of sexual transmission
    Zhiwei Wu
    Department of Biochemistry, School of Dental Medicine, University of Pennsylvania, Philadelphia 19104, USA
    J Infect Dis 188:1473-82. 2003
    ..Genital epithelial cells may play active roles in sequestering, protecting, and transferring virus during sexual transmission of HIV...
  11. ncbi request reprint Assay for establishing whether microbicide applicators have been exposed to the vagina
    Andrea Wallace
    Population Council, New York, New York 10021, USA
    Sex Transm Dis 31:465-8. 2004
    ..To develop an accurate, rapid, and inexpensive method for verifying vaginal applicator use...
  12. ncbi request reprint Carrageenan/MIV-150 (PC-815), a combination microbicide
    Jose A Fernández-Romero
    Population Council, New York, NY, USA
    Sex Transm Dis 34:9-14. 2007
    ....

Research Grants2

  1. Novel anti-HIV carrageenan-based on microbicides
    David Phillips; Fiscal Year: 2004
    ..The applicant believes that the proposed research will result in the pre-clinical development of a safe, novel microbicide that is superior in efficacy against HIV. ..
  2. Partnership for developing broad-spectrum microbicides
    David Phillips; Fiscal Year: 2007
    ..Our goals are to improve the formulation's efficacy against a broader range of sexually transmitted diseases (STDs) and increase its strength by adding anti-viral compounds that are active against HIV-1, HIV-2, HBV and HSV-2. ..