Jack Henningfield

Summary

Affiliation: Pinney Associates
Country: USA

Publications

  1. ncbi request reprint Tobacco dependence. Global public health potential for new medications development and indications
    J E Henningfield
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Ann N Y Acad Sci 909:247-56. 2000
  2. pmc Regulatory strategies to reduce tobacco addiction in youth
    J E Henningfield
    Johns Hopkins University School of Medicine, Pinney Associates, Bethesda, MD 20814, USA
    Tob Control 12:i14-24. 2003
  3. ncbi request reprint C. Everett Koop, M.D., Sc.D.: a visionary leader of science-based public health policy and tobacco control
    Jack E Henningfield
    Johns Hopkins University School of Medicine and Pinney Associates, Bethesda MD 20814, USA
    Nicotine Tob Res 5:611-2. 2003
  4. ncbi request reprint Menthol cigarettes: research needs and challenges
    Jack E Henningfield
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Nicotine Tob Res 6:S11-6. 2004
  5. pmc Reducing tobacco addiction through tobacco product regulation
    J E Henningfield
    Pinney Associates, Inc, 4800 Montgomery Lane, Suite 1000, Bethesda, MD 20814, USA
    Tob Control 13:132-5. 2004
  6. ncbi request reprint Ammonia and other chemical base tobacco additives and cigarette nicotine delivery: issues and research needs
    Jack Henningfield
    Department of Psychiatry and Behavioral Sciences Johns Hopkins University School of Medicine, Baltimore MD, USA
    Nicotine Tob Res 6:199-205. 2004
  7. pmc Clean cut cigarettes: fictitious launch foreshadows actual tobacco industry strategy
    Jack E Henningfield
    Pinney Associates, Bethesda, Maryland, and Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Tob Control 15:341-2. 2006
  8. ncbi request reprint Nicotine psychopharmacology research contributions to United States and global tobacco regulation: a look back and a look forward
    Jack E Henningfield
    Pinney Associates, 3 Bethesda Metro Center, Suite 1400, Bethesda, MD 20814, USA
    Psychopharmacology (Berl) 184:286-91. 2006
  9. ncbi request reprint Medications work for severely addicted smokers: implications for addiction therapists and primary care physicians
    Jack E Henningfield
    Johns Hopkins University School of Medicine and Pinney Associates, Inc, 3 Bethesda Metro Center, Suite 1400, Bethesda, MD 20814, USA
    J Subst Abuse Treat 28:1-2. 2005
  10. ncbi request reprint Guidance for research and testing to reduce tobacco toxicant exposure
    Jack E Henningfield
    Pinney Associates and Johns Hopkins University School of Medicine, Baltimore, MD 20814, USA
    Nicotine Tob Res 7:821-6. 2005

Detail Information

Publications46

  1. ncbi request reprint Tobacco dependence. Global public health potential for new medications development and indications
    J E Henningfield
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Ann N Y Acad Sci 909:247-56. 2000
    ..This article discusses the biobehavioral rationale for medication development, the opportunities, and some of the prominent technical and regulatory challenges...
  2. pmc Regulatory strategies to reduce tobacco addiction in youth
    J E Henningfield
    Johns Hopkins University School of Medicine, Pinney Associates, Bethesda, MD 20814, USA
    Tob Control 12:i14-24. 2003
    ..We conclude that although some carry great risk, others may actually support broader tobacco control efforts to prevent tobacco use and foster cessation in youth and adults...
  3. ncbi request reprint C. Everett Koop, M.D., Sc.D.: a visionary leader of science-based public health policy and tobacco control
    Jack E Henningfield
    Johns Hopkins University School of Medicine and Pinney Associates, Bethesda MD 20814, USA
    Nicotine Tob Res 5:611-2. 2003
  4. ncbi request reprint Menthol cigarettes: research needs and challenges
    Jack E Henningfield
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Nicotine Tob Res 6:S11-6. 2004
  5. pmc Reducing tobacco addiction through tobacco product regulation
    J E Henningfield
    Pinney Associates, Inc, 4800 Montgomery Lane, Suite 1000, Bethesda, MD 20814, USA
    Tob Control 13:132-5. 2004
    ..Tobacco product regulation has the potential to help reduce tobacco attributable disease by reducing the toxicity of these products and by reducing the prevalence of tobacco use and addiction...
  6. ncbi request reprint Ammonia and other chemical base tobacco additives and cigarette nicotine delivery: issues and research needs
    Jack Henningfield
    Department of Psychiatry and Behavioral Sciences Johns Hopkins University School of Medicine, Baltimore MD, USA
    Nicotine Tob Res 6:199-205. 2004
  7. pmc Clean cut cigarettes: fictitious launch foreshadows actual tobacco industry strategy
    Jack E Henningfield
    Pinney Associates, Bethesda, Maryland, and Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Tob Control 15:341-2. 2006
    ..A fictitious cigarette brand, "launched" at the 11th World Conference on Tobacco or Health, appears to have been adopted by Philip Morris...
  8. ncbi request reprint Nicotine psychopharmacology research contributions to United States and global tobacco regulation: a look back and a look forward
    Jack E Henningfield
    Pinney Associates, 3 Bethesda Metro Center, Suite 1400, Bethesda, MD 20814, USA
    Psychopharmacology (Berl) 184:286-91. 2006
    ..Psychopharmacology research has been pivotal in the science foundation for nicotine and tobacco product regulation...
  9. ncbi request reprint Medications work for severely addicted smokers: implications for addiction therapists and primary care physicians
    Jack E Henningfield
    Johns Hopkins University School of Medicine and Pinney Associates, Inc, 3 Bethesda Metro Center, Suite 1400, Bethesda, MD 20814, USA
    J Subst Abuse Treat 28:1-2. 2005
  10. ncbi request reprint Guidance for research and testing to reduce tobacco toxicant exposure
    Jack E Henningfield
    Pinney Associates and Johns Hopkins University School of Medicine, Baltimore, MD 20814, USA
    Nicotine Tob Res 7:821-6. 2005
  11. ncbi request reprint Does menthol enhance the addictiveness of cigarettes? An agenda for research
    Jack E Henningfield
    Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Nicotine Tob Res 5:9-11. 2003
  12. pmc Tobacco industry litigation position on addiction: continued dependence on past views
    Jack E Henningfield
    Pinney Associates, Bethesda, Maryland, USA
    Tob Control 15:iv27-36. 2006
    ..These positions have been maintained through the 2004-2005 US Government litigation that was ongoing as the time of this writing...
  13. pmc Tobacco dependence and withdrawal: science base, challenges and opportunities for pharmacotherapy
    Jack E Henningfield
    Pinney Associates, Bethesda, Maryland 20814, USA
    Pharmacol Ther 123:1-16. 2009
    ..Research on more effective medication use along with policies that support improved access and utilization are vital to conquering the tobacco epidemic...
  14. ncbi request reprint Prevention of nicotine addiction: neuropsychopharmacological issues
    J E Henningfield
    Department of Psychiatry and Behavioral Science, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Nicotine Tob Res 1:S41-8. 1999
    ..The barriers may be better understood by a brief summary of what neuropsychopharmacology research involves, and a corresponding summary of the disincentives to conduct such research...
  15. doi request reprint Risk management and post-marketing surveillance of CNS drugs
    Jack E Henningfield
    The Johns Hopkins University School of Medicine, Baltimore, MD 21229, USA
    Drug Alcohol Depend 105:S56-64. 2009
    ..How such issues are resolved has the potential to stimulate or stifle innovations in drug development and advance or imperil health care...
  16. ncbi request reprint Tobacco use as drug addiction: the scientific foundation
    J E Henningfield
    Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Nicotine Tob Res 1:S31-5. 1999
    ....
  17. doi request reprint Tobacco psychopharmacology and public health policy: it takes a community
    Jack E Henningfield
    Pinney Associates, Bethesda, MD 20814, USA
    Exp Clin Psychopharmacol 19:249-62. 2011
    ....
  18. ncbi request reprint Treatment of adolescent tobacco smokers: issues and opportunities for exposure reduction approaches
    Eric T Moolchan
    Intramural Research Program, Clinical Pharmacology and Therapeutics Research Branch, National Institute on Drug Abuse, National Institutes of Health, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    Drug Alcohol Depend 70:223-32. 2003
    ....
  19. ncbi request reprint Dissent over harm reduction for tobacco
    Nigel Gray
    Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Lancet 368:899-901. 2006
  20. ncbi request reprint Novel pharmacological approaches for treating tobacco dependence and withdrawal: current status
    August R Buchhalter
    Pinney Associates, Bethesda, Maryland 20814, USA
    Drugs 68:1067-88. 2008
    ..Having not been approved by major drug regulatory authorities for the treatment of tobacco dependence and/or withdrawal, these medications have been evaluated in an experimental capacity...
  21. ncbi request reprint Nicotine delivery systems
    Saul Shiffman
    University of Pittsburgh Smoking Research Group, Department of Psychology, Pittsburgh, PA, USA
    Expert Opin Drug Deliv 2:563-77. 2005
    ..New applications of existing and novel medicinal nicotine products may include relapse prevention, nicotine maintenance, temporary withdrawal management, reduced smoking and gradual quitting...
  22. doi request reprint Case histories in pharmaceutical risk management
    Cynthia G McCormick
    McCormick Consultation, LLC, Bethesda, MD 20817, USA
    Drug Alcohol Depend 105:S42-55. 2009
    ....
  23. ncbi request reprint Tobacco harm reduction: conceptual structure and nomenclature for analysis and research
    Saul Shiffman
    Pinney Associates, Pittsburgh, PA 15213, USA
    Nicotine Tob Res 4:S113-29. 2002
    ..The suggested framework is intended to clarify the debate, provide for common nomenclature, and facilitate analysis of diverse approaches to tobacco harm reduction...
  24. ncbi request reprint Could science-based regulation make tobacco products less addictive?
    Jack E Henningfield
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, USA
    Yale J Health Policy Law Ethics 3:127-38. 2002
  25. doi request reprint The Strategic Dialogue on Tobacco Harm Reduction: a vision and blueprint for action in the US
    Mitchell Zeller
    Pinney Associates, 3 Bethesda Metro Center, Suite 1400, Bethesda, MD 20814, USA
    Tob Control 18:324-32. 2009
    ..Short-term and long-term objectives are described...
  26. ncbi request reprint Nicotine dependence criteria of the DIS and DSM-III-R: a factor analysis
    Aleksandras Radzius
    National Institutes of Health, National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD, USA
    Nicotine Tob Res 6:303-8. 2004
    ....
  27. ncbi request reprint Pharmacotherapy for nicotine dependence
    Jack E Henningfield
    Clinical Pharmacology, Pinney Associates, Bethesda, MD, USA
    CA Cancer J Clin 55:281-99; quiz 322-3, 325. 2005
    ..Increasing the treatment options, increasing availability, and reducing the perceived cost of these medications may have an additional public health impact...
  28. pmc Nicotine reduction: strategic research plan
    Dorothy K Hatsukami
    Department of Psychiatry, University of Minnesota, Minneapolis, MN 55414, USA
    Nicotine Tob Res 15:1003-13. 2013
    ..Many experts have considered reducing nicotine in cigarettes to be a feasible national policy approach, but more research is necessary...
  29. ncbi request reprint Calorie restriction increases cigarette use in adult smokers
    Lawrence J Cheskin
    Department of Health and Human Services, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224, USA
    Psychopharmacology (Berl) 179:430-6. 2005
    ..This concern derives, in part, from the observation that calorie restriction increases self-administration of drugs of abuse in animals. This relationship has never been experimentally demonstrated in humans...
  30. ncbi request reprint Subjective effects of the nicotine lozenge: assessment of abuse liability
    Elisabeth J Houtsmuller
    Behavioral Pharmacology Research Unit, Johns Hopkins University School of Medicine, Bayview Medical Center, 5510 Nathan Shock Drive, MD 21224 6823, Baltimore, USA
    Psychopharmacology (Berl) 167:20-7. 2003
    ..However, its resemblance to commercially marketed lozenges and its palatability, intended to increase medication compliance, may increase its abuse liability, especially among younger individuals...
  31. ncbi request reprint Flavor improvement does not increase abuse liability of nicotine chewing gum
    Elisabeth J Houtsmuller
    Behavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences, Bayview Medical Center, Johns Hopkins University School of Medicine, Baltimore, MD 21224 6823, USA
    Pharmacol Biochem Behav 72:559-68. 2002
    ..Younger subjects reported fewer withdrawal symptoms and lower ratings for drug effects and flavor. Improved flavor of nicotine gum does not increase abuse liability, but may be associated with enhanced craving reduction...
  32. ncbi request reprint The Fagerstrom Test for Nicotine Dependence and the Diagnostic Interview Schedule: do they diagnose the same smokers?
    Eric T Moolchan
    Clinical Pharmacology and Therapeutics Research Branch, National Institutes of Health, National Institute on Drug Abuse Intramural Research Program, Baltimore MD, 21224, USA
    Addict Behav 27:101-13. 2002
    ..Disagreements between the FTND and the DSM are likely to become greater with the changes in the DSM-IV...
  33. ncbi request reprint Nicotine serves as an effective reinforcer of intravenous drug-taking behavior in human cigarette smokers
    Deon M Harvey
    Clinical Pharmacology and Therapeutics Branch, National Institute on Drug Abuse, NIH, DHHS, Baltimore, MD 21224, USA
    Psychopharmacology (Berl) 175:134-42. 2004
    ....
  34. ncbi request reprint Correlation between pharmacological effects and plasma cocaine concentrations after smoked administration
    Amanda J Jenkins
    Addiction Research Center, Intramural Research Program, National Institute on Drug Abuse, NIH, Baltimore, Maryland 21224, USA
    J Anal Toxicol 26:382-92. 2002
    ..Several subjective and cardiovascular measures returned to baseline levels in the presence of detectable concentrations of cocaine...
  35. ncbi request reprint Intravenous nicotine reduces cerebral glucose metabolism: a preliminary study
    June M Stapleton
    Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, USA
    Neuropsychopharmacology 28:765-72. 2003
    ..The findings indicate that nicotine resembles other drugs of abuse in reducing brain metabolism, perhaps by a common mechanism...
  36. ncbi request reprint Exploitation by design-could tobacco industry documents guide more effective smoking prevention and cessation in women?
    Jack E Henningfield
    Addiction 100:735-6. 2005
  37. ncbi request reprint Nicotine psychopharmacology research: advancing science, public health, and global policy
    Jack E Henningfield
    Psychopharmacology (Berl) 184:263-5. 2006
  38. doi request reprint Tobacco industry research and efforts to manipulate smoke particle size: implications for product regulation
    Geoffrey Ferris Wayne
    Tobacco Control Research Program, Harvard School of Public Health, Boston, MA, USA
    Nicotine Tob Res 10:613-25. 2008
    ....
  39. ncbi request reprint A long-term view of harm reduction
    Nigel J Gray
    Directors Office, International Agency for Research on Cancer, 150 cours Albert Thomas, 69372 Lyon 08, France
    Nicotine Tob Res 6:759-64. 2004
    ..The risks potentially associated with reducing levels of known toxicants in cigarettes are tiny in comparison with the acceptance of the status quo, which is disastrous. Failure to act in these circumstances is negligence...
  40. ncbi request reprint Brave new world of tobacco disease prevention: promoting dual tobacco-product use?
    Jack E Henningfield
    Am J Prev Med 23:226-8. 2002
  41. ncbi request reprint Eclipse can deliver crack cocaine
    Stacey L Steckley
    Nicotine Tob Res 4:S189-90. 2002
  42. ncbi request reprint Tobacco, nicotine, and human cognition
    Stephen J Heishman
    Nicotine Tob Res 4:3-4. 2002
  43. ncbi request reprint Relationship between plasma and oral fluid nicotine concentrations in humans: a pilot study
    Amanda J Jenkins
    The Office of the Cuyahoga County Coroner, Cleveland, Ohio 44106, USA
    Ther Drug Monit 27:345-8. 2005
    ..Oral fluid/plasma were >1 for up to 60 minutes after the low dose and 120 minutes after the high dose. There was no correlation between plasma and oral fluid nicotine concentrations...
  44. ncbi request reprint Assessing internal tobacco industry knowledge of the neurobiology of tobacco dependence
    Geoffrey Ferris Wayne
    Massachusetts Department of Public Health, USA
    Nicotine Tob Res 6:927-40. 2004
    ..We conclude that clinical research would greatly benefit from further examination of the decades of knowledge accumulated by tobacco manufacturers...
  45. ncbi request reprint Harm reduction approaches to reducing tobacco-related mortality
    Dorothy K Hatsukami
    University of Minnesota, Tobacco Use Research Center, Minneapolis, Minnesota 55414, USA
    Annu Rev Public Health 25:377-95. 2004
    ..A significant amount of independent research is needed to inform policy decisions. Regulatory authority over potential reduced exposure products is also essential...
  46. ncbi request reprint Impact of formulation on the abuse liability, safety and regulation of medications: the expert panel report
    Charles Grudzinskas
    NDA Partners LLC, 720 Riverview Terrace, Annapolis, MD 21401, USA
    Drug Alcohol Depend 83:S77-82. 2006
    ..Finally, knowledge and experience are needed to translate scientific work into a predictable, transparent and reliable regulatory process...