Pooja Hingorani

Summary

Affiliation: Phoenix Children's Hospital
Country: USA

Publications

  1. pmc Body mass index (BMI) at diagnosis is associated with surgical wound complications in patients with localized osteosarcoma: a report from the Children's Oncology Group
    Pooja Hingorani
    Division of Pediatric Hematology Oncology, Phoenix Children s Hospital, Phoenix, Arizona 85016, USA
    Pediatr Blood Cancer 57:939-42. 2011
  2. doi Clinical Application of Prognostic Gene Expression Signature in Fusion Gene-Negative Rhabdomyosarcoma: A Report from the Children's Oncology Group
    Pooja Hingorani
    Center for Cancer and Blood Disorders, Phoenix Children s Hospital, Phoenix, Arizona
    Clin Cancer Res 21:4733-9. 2015
  3. doi Oncolytic viruses for potential osteosarcoma therapy
    Pooja Hingorani
    Center for Cancer and Blood Disorders, Phoenix Children s Hospital, 1919 E Thomas Road, Phoenix, AZ, 85016, USA
    Adv Exp Med Biol 804:259-83. 2014
  4. ncbi Gemcitabine, docetaxel, and bevacizumab in relapsed and refractory pediatric sarcomas
    Pooja Hingorani
    Division of Hematology, Phoenix Children s Hospital, Phoenix, AZ 85016, USA
    J Pediatr Hematol Oncol 34:524-7. 2012
  5. doi BIRC5 expression is a poor prognostic marker in Ewing sarcoma
    Pooja Hingorani
    Center for Cancer and Blood Disorders, Phoenix Children s Hospital, Phoenix, AZ 85016, USA
    Pediatr Blood Cancer 60:35-40. 2013
  6. doi Past, present and future of therapies in pediatric sarcomas
    Pooja Hingorani
    Department of Pediatric Hematology Oncology, Phoenix Childrens Hospital, 1919 E Thomas Road, Phoenix, AZ 85003, USA
    Future Oncol 6:605-18. 2010
  7. doi Systemic administration of reovirus (Reolysin) inhibits growth of human sarcoma xenografts
    Pooja Hingorani
    Department of Pediatric Hematology Oncology, Phoenix Children s Hospital, Phoenix, Arizona 85016, USA
    Cancer 117:1764-74. 2011
  8. doi Inhibition of Src phosphorylation alters metastatic potential of osteosarcoma in vitro but not in vivo
    Pooja Hingorani
    Department of Pediatric Hematology Oncology, Phoenix Children s Hospital, Phoenix, AZ 85016, USA
    Clin Cancer Res 15:3416-22. 2009
  9. doi Preclinical activity of palifosfamide lysine (ZIO-201) in pediatric sarcomas including oxazaphosphorine-resistant osteosarcoma
    Pooja Hingorani
    Department of Pediatric Hematology Oncology, Phoenix Childrens Hospital, Phoenix, AZ 85003, USA
    Cancer Chemother Pharmacol 64:733-40. 2009
  10. doi Progress of oncolytic viruses in sarcomas
    Christina K Lettieri
    Center for Cancer and Blood Disorders, Phoenix Children s Hospital, Phoenix, AZ 85016, USA
    Expert Rev Anticancer Ther 12:229-42. 2012

Collaborators

Detail Information

Publications11

  1. pmc Body mass index (BMI) at diagnosis is associated with surgical wound complications in patients with localized osteosarcoma: a report from the Children's Oncology Group
    Pooja Hingorani
    Division of Pediatric Hematology Oncology, Phoenix Children s Hospital, Phoenix, Arizona 85016, USA
    Pediatr Blood Cancer 57:939-42. 2011
    ..We investigated the role of body mass index (BMI) on the incidence of surgical wound complications in patients with localized osteosarcoma treated on the Children's Oncology Group (COG) legacy trial, INT-0133...
  2. doi Clinical Application of Prognostic Gene Expression Signature in Fusion Gene-Negative Rhabdomyosarcoma: A Report from the Children's Oncology Group
    Pooja Hingorani
    Center for Cancer and Blood Disorders, Phoenix Children s Hospital, Phoenix, Arizona
    Clin Cancer Res 21:4733-9. 2015
    ..The goal of this study was to test whether expression of the MG5 metagene, measured using a technical platform that can be applied to routine pathology material, would correlate with outcome in a new cohort of patients with FN-RMS...
  3. doi Oncolytic viruses for potential osteosarcoma therapy
    Pooja Hingorani
    Center for Cancer and Blood Disorders, Phoenix Children s Hospital, 1919 E Thomas Road, Phoenix, AZ, 85016, USA
    Adv Exp Med Biol 804:259-83. 2014
    ..In this review we summarize the supportive evidence and rationale for use of viral oncolysis in osteosarcoma along with the specific challenges it may face. ..
  4. ncbi Gemcitabine, docetaxel, and bevacizumab in relapsed and refractory pediatric sarcomas
    Pooja Hingorani
    Division of Hematology, Phoenix Children s Hospital, Phoenix, AZ 85016, USA
    J Pediatr Hematol Oncol 34:524-7. 2012
    ..The outcome for patients with relapsed and refractory pediatric sarcomas remains dismal. Novel agents are needed to improve overall survival in these patients...
  5. doi BIRC5 expression is a poor prognostic marker in Ewing sarcoma
    Pooja Hingorani
    Center for Cancer and Blood Disorders, Phoenix Children s Hospital, Phoenix, AZ 85016, USA
    Pediatr Blood Cancer 60:35-40. 2013
    ..The goal of the current study was to evaluate the role of BIRC5 in Ewing sarcoma (ES), the second most common pediatric bone sarcoma...
  6. doi Past, present and future of therapies in pediatric sarcomas
    Pooja Hingorani
    Department of Pediatric Hematology Oncology, Phoenix Childrens Hospital, 1919 E Thomas Road, Phoenix, AZ 85003, USA
    Future Oncol 6:605-18. 2010
    ..This article discusses the successes, the failures and the future direction of these therapies...
  7. doi Systemic administration of reovirus (Reolysin) inhibits growth of human sarcoma xenografts
    Pooja Hingorani
    Department of Pediatric Hematology Oncology, Phoenix Children s Hospital, Phoenix, Arizona 85016, USA
    Cancer 117:1764-74. 2011
    ..Reolysin is an unmodified oncolytic reovirus that selectively replicates in Ras-activated cancer cells while not causing any significant human illness in its wild form...
  8. doi Inhibition of Src phosphorylation alters metastatic potential of osteosarcoma in vitro but not in vivo
    Pooja Hingorani
    Department of Pediatric Hematology Oncology, Phoenix Children s Hospital, Phoenix, AZ 85016, USA
    Clin Cancer Res 15:3416-22. 2009
    ..We studied the effect of inhibition of Src phosphorylation in preventing the growth and development of pulmonary metastases in osteosarcoma...
  9. doi Preclinical activity of palifosfamide lysine (ZIO-201) in pediatric sarcomas including oxazaphosphorine-resistant osteosarcoma
    Pooja Hingorani
    Department of Pediatric Hematology Oncology, Phoenix Childrens Hospital, Phoenix, AZ 85003, USA
    Cancer Chemother Pharmacol 64:733-40. 2009
    ..In the current study, the activity of palifosfamide lysine (ZIO-201), a stable form of palifosfamide, was evaluated in a panel of sarcoma cell lines and tumor xenografts including oxazaphosphorine-resistant xenografts...
  10. doi Progress of oncolytic viruses in sarcomas
    Christina K Lettieri
    Center for Cancer and Blood Disorders, Phoenix Children s Hospital, Phoenix, AZ 85016, USA
    Expert Rev Anticancer Ther 12:229-42. 2012
    ..Further understanding of the antiviral immune response and a viral induced anti-tumor immune response will permit a maximization of oncolytic virotherapy...
  11. doi Enhanced T-cell immunity to osteosarcoma through antibody blockade of PD-1/PD-L1 interactions
    Danielle M Lussier
    Molecular and Cellular Biology Graduate Program Center for Infectious Diseases and Vaccinology Molecular Biosciences and Biotechnology Postbaccalaureate Research Education Program, School of Life Sciences, Arizona State University, Tempe Center for Cancer and Blood Disorders Department of Pathology and Laboratory Medicine, Phoenix Children s Hospital Department of Child Health, University of Arizona College of Medicine Phoenix, Phoenix, AZ
    J Immunother 38:96-106. 2015
    ..Our results suggest that blockade of PD-1/PD-L1 interactions in patients with metastatic osteosarcoma should be pursued as a therapeutic strategy. ..