- The sequence, crystal structure determination and refinement of two crystal forms of lipase B from Candida antarcticaJ Uppenberg
Department of Molecular Biology, Uppsala University, Sweden
Structure 2:293-308. 1994..In recent years, much progress has been made towards explaining the mechanism of these enzymes and their ability to hydrolyze their substrates at an oil-water interface...
- Crystal structure of the ligand binding domain of the human nuclear receptor PPARgammaJ Uppenberg
Department of Structural Chemistry, Pharmacia and Upjohn, Lindhagensgatan 133, S 112 87 Stockholm, Sweden
J Biol Chem 273:31108-12. 1998..Given the central role of PPARgamma as a mediator in glucose regulation, the structure should be an important tool in the development of improved anti-diabetic agents...
- Crystal structure of a mammalian purple acid phosphataseJ Uppenberg
Department of Structural Chemistry, Pharmacia and Upjohn, Lindhagensgatan 133, Stockholm, S 112 87, Sweden
J Mol Biol 290:201-11. 1999..The current structure was determined at a relatively high pH and without any external reducing agents. It is likely that it represents an oxidized and therefore catalytically inactive form of the enzyme...