Affiliation: Pharmacia Corporation
- Therapeutic potential of selective cyclooxygenase-2 inhibitors in the management of tumor angiogenesisStephen Gately
NeoPharm Inc, Department of Translational Medicine, Lake Forest, Ill, USA
Prog Exp Tumor Res 37:179-92. 2003..The continued dependence on angiogenesis for later stages of tumorigenesis suggests that COX-2 inhibitors also will have clinical utility in the management of advanced cancers...
- Multiple roles of COX-2 in tumor angiogenesis: a target for antiangiogenic therapyStephen Gately
Department of Translational Medicine, NeoPharm Inc, 150 Field Drive, Suite 195, Lake Forest, IL 60045, USA
Semin Oncol 31:2-11. 2004....
- Tumor production of angiostatin is enhanced after exposure to TNF-alphaHelena J Mauceri
Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL 60637, USA
Int J Cancer 97:410-5. 2002..These studies support a model in which the antiangiogenic effects of TNF-alpha on the tumor microvasculature are mediated by generation of angiostatin...