Robert W Mays

Summary

Affiliation: Pharmaceutical Products Division
Country: USA

Publications

  1. ncbi Development of adult pluripotent stem cell therapies for ischemic injury and disease
    Robert W Mays
    Athersys, Inc, Division of Regenerative Medicine, 3201 Carnegie Avenue, Cleveland, OH 44115, USA
    Expert Opin Biol Ther 7:173-84. 2007
  2. pmc Intravenous multipotent adult progenitor cell therapy after traumatic brain injury: modulation of the resident microglia population
    Peter A Walker
    Department of Surgery, University of Texas Medical School at Houston, 6431 Fannin Street, MSB 5 236, Houston, TX 77030, USA
    J Neuroinflammation 9:228. 2012
  3. ncbi Isosteric ramatroban analogs: selective and potent CRTH-2 antagonists
    Michael J Robarge
    Athersys, Inc, Medicinal Chemistry, 3201 Carnegie Avenue, Cleveland, OH 44115 2634, USA
    Bioorg Med Chem Lett 15:1749-53. 2005
  4. doi 3-Indolyl sultams as selective CRTh2 antagonists
    L Nathan Tumey
    Athersys, Inc, 3201 Carnegie Ave, Cleveland, OH 44115, USA
    Bioorg Med Chem Lett 20:3287-90. 2010
  5. ncbi Therapeutic pathways of adult stem cell repair
    Anthony E Ting
    Division of Regenerative Medicine, Athersys Inc, 3201 Carnegie Avenue, Cleveland, OH 44115, USA
    Crit Rev Oncol Hematol 65:81-93. 2008
  6. pmc Multipotent adult progenitor cells prevent macrophage-mediated axonal dieback and promote regrowth after spinal cord injury
    Sarah A Busch
    Department of Neurosciences, Case Western Reserve University, Cleveland, Ohio 44106, USA
    J Neurosci 31:944-53. 2011
  7. ncbi Behavioral and histological characterization of intrahippocampal grafts of human bone marrow-derived multipotent progenitor cells in neonatal rats with hypoxic-ischemic injury
    Takao Yasuhara
    Department of Neurology, Medical College of Georgia, Augusta, GA 30912, USA
    Cell Transplant 15:231-8. 2006
  8. pmc Intravenous grafts recapitulate the neurorestoration afforded by intracerebrally delivered multipotent adult progenitor cells in neonatal hypoxic-ischemic rats
    Takao Yasuhara
    Department of Neurology, Medical College of Georgia, Augusta, Georgia 30912 3200, USA
    J Cereb Blood Flow Metab 28:1804-10. 2008

Collaborators

  • Anthony E Ting
  • L Nathan Tumey
  • Youssef L Bennani
  • Jerry Silver
  • David Hess
  • C V Borlongan
  • Takao Yasuhara
  • Peter A Walker
  • Jason A Hamilton
  • Sarah A Busch
  • Michael J Robarge
  • Hasen Xue
  • Shinil K Shah
  • Charles S Cox
  • Fernando Jimenez
  • Philippa Smith
  • Chelsea P Thomas
  • Supinder S Bedi
  • Shibani Pati
  • Robert J Deans
  • Rochelle Cutrone
  • Fernando X Cuascut
  • Nicholas Lehman
  • Kevin P Horn
  • Margaret Loftus
  • Gary Pawlowski
  • Steven M Murphy
  • George Ekema
  • John J Harrington
  • David C Bom
  • Doug Hanniford
  • Chris Doucette
  • Bruce A Sherf
  • Marc Palmer
  • Daniel Silver
  • Kurt R Brunden
  • Norbert Varga
  • Elizabeth Gleason
  • Karen Hunady
  • Jianping Song
  • Alain Stricker-Krongrad
  • Joel Danzig

Detail Information

Publications8

  1. ncbi Development of adult pluripotent stem cell therapies for ischemic injury and disease
    Robert W Mays
    Athersys, Inc, Division of Regenerative Medicine, 3201 Carnegie Avenue, Cleveland, OH 44115, USA
    Expert Opin Biol Ther 7:173-84. 2007
    ..In this article, the authors review preclinical animal data demonstrating the benefit of pluripotent adult progenitor cells in the treatment of ischemic injuries of the heart, vascular system and CNS...
  2. pmc Intravenous multipotent adult progenitor cell therapy after traumatic brain injury: modulation of the resident microglia population
    Peter A Walker
    Department of Surgery, University of Texas Medical School at Houston, 6431 Fannin Street, MSB 5 236, Houston, TX 77030, USA
    J Neuroinflammation 9:228. 2012
    ..We hypothesize that the observed modulation of the systemic inflammatory milieu is related to T regulatory cells and a subsequent increase in the locoregional neuroprotective M2 macrophage population...
  3. ncbi Isosteric ramatroban analogs: selective and potent CRTH-2 antagonists
    Michael J Robarge
    Athersys, Inc, Medicinal Chemistry, 3201 Carnegie Avenue, Cleveland, OH 44115 2634, USA
    Bioorg Med Chem Lett 15:1749-53. 2005
    ..In this report, we describe the synthesis and optimization of a ramatroban isostere that is a selective and potent antagonist of CRTH-2 which may be useful in the treatment of certain diseases...
  4. doi 3-Indolyl sultams as selective CRTh2 antagonists
    L Nathan Tumey
    Athersys, Inc, 3201 Carnegie Ave, Cleveland, OH 44115, USA
    Bioorg Med Chem Lett 20:3287-90. 2010
    ..These compounds proved to be selective over the other primary prostaglandin D(2) receptor (DP1) as well as the thromboxane A(2) receptor (TP)...
  5. ncbi Therapeutic pathways of adult stem cell repair
    Anthony E Ting
    Division of Regenerative Medicine, Athersys Inc, 3201 Carnegie Avenue, Cleveland, OH 44115, USA
    Crit Rev Oncol Hematol 65:81-93. 2008
    ....
  6. pmc Multipotent adult progenitor cells prevent macrophage-mediated axonal dieback and promote regrowth after spinal cord injury
    Sarah A Busch
    Department of Neurosciences, Case Western Reserve University, Cleveland, Ohio 44106, USA
    J Neurosci 31:944-53. 2011
    ..Our results demonstrate that MAPCs have therapeutic benefits after spinal cord injury and provide specific evidence that adult stem cells exert positive immunomodulatory and neurotrophic influences...
  7. ncbi Behavioral and histological characterization of intrahippocampal grafts of human bone marrow-derived multipotent progenitor cells in neonatal rats with hypoxic-ischemic injury
    Takao Yasuhara
    Department of Neurology, Medical College of Georgia, Augusta, GA 30912, USA
    Cell Transplant 15:231-8. 2006
    ..An equally major finding is the observation lending support to the hippocampus as an excellent target brain region for stem cell therapy in treating HI injury...
  8. pmc Intravenous grafts recapitulate the neurorestoration afforded by intracerebrally delivered multipotent adult progenitor cells in neonatal hypoxic-ischemic rats
    Takao Yasuhara
    Department of Neurology, Medical College of Georgia, Augusta, Georgia 30912 3200, USA
    J Cereb Blood Flow Metab 28:1804-10. 2008
    ..These results show that intravenous delivery of MAPCs is a feasible and efficacious cell therapy with potential for clinical use...