A W Schmidt
Affiliation: Pfizer Global Research and Development
- Ziprasidone: a novel antipsychotic agent with a unique human receptor binding profileA W Schmidt
CNS Discovery, Groton Laboratories, Pfizer Global Research and Development, MS 8220 4155, 558 Eastern Point Road, Groton, CT 06340 1596, USA
Eur J Pharmacol 425:197-201. 2001....
- Clozapine increases dopamine release in prefrontal cortex by 5-HT1A receptor activationH Rollema
Pfizer Inc, Department of Neuroscience, Groton, CT 06340, USA
Eur J Pharmacol 338:R3-5. 1997..Agonist affinity for 5-HT1A receptors could thus be a desirable feature in the design of new antipsychotics...
- Pharmacological characterization of 2-methyl-N-((2'-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine (PF-04455242), a high-affinity antagonist selective for κ-opioid receptorsS Grimwood
Neuroscience Research Unit, Pfizer Inc, Groton, CT 06340, USA
J Pharmacol Exp Ther 339:555-66. 2011..1 mg/kg, which aligned well with the ED(50) values obtained from the rat in vivo binding and efficacy assays. These data provide further evidence that KOR antagonists have potential for the treatment of depression and addiction disorders...
- Serotonergic effects and extracellular brain levels of eletriptan, zolmitriptan and sumatriptan in rat brainD E Johnson
Department of Neuroscience, Pfizer Global Research and Development, MS 8220-4159, Groton, CT 06340, USA
Eur J Pharmacol 425:203-10. 2001....