Andres D Ramirez

Summary

Affiliation: Pfizer Global Research and Development
Country: USA

Publications

  1. ncbi request reprint Repeated estradiol treatment prevents MPTP-induced dopamine depletion in male mice
    Andres D Ramirez
    CNS Discovery, Pfizer Global Research and Development, Groton, Conn, USA
    Neuroendocrinology 77:223-31. 2003
  2. ncbi request reprint Pramipexole inhibits MPTP toxicity in mice by dopamine D3 receptor dependent and independent mechanisms
    Andres D Ramirez
    CNS Discovery, Pfizer Global Research and Development, MS 8220 4130, Eastern Point Road Bldg 100, Groton, CT 06340, USA
    Eur J Pharmacol 475:29-35. 2003
  3. ncbi request reprint Role of estrogen receptors in neuroprotection by estradiol against MPTP toxicity
    Marc Morissette
    Molecular Endocrinology and Oncology Research Center, Laval University Medical Center, Quebec City, QC, Canada
    Neuropharmacology 52:1509-20. 2007

Collaborators

Detail Information

Publications3

  1. ncbi request reprint Repeated estradiol treatment prevents MPTP-induced dopamine depletion in male mice
    Andres D Ramirez
    CNS Discovery, Pfizer Global Research and Development, Groton, Conn, USA
    Neuroendocrinology 77:223-31. 2003
    ..In this study, raloxifene failed to mimic the neuroprotective effect of 17beta-estradiol against MPTP toxicity. Thus, exploration of new compounds with different pharmacological and/or physiochemical properties is warranted...
  2. ncbi request reprint Pramipexole inhibits MPTP toxicity in mice by dopamine D3 receptor dependent and independent mechanisms
    Andres D Ramirez
    CNS Discovery, Pfizer Global Research and Development, MS 8220 4130, Eastern Point Road Bldg 100, Groton, CT 06340, USA
    Eur J Pharmacol 475:29-35. 2003
    ..These results indicate that pramipexole protects dopamine neurons from MPTP-induced toxicity by mechanisms that are both dependent and independent of an interaction with dopamine D3 receptors...
  3. ncbi request reprint Role of estrogen receptors in neuroprotection by estradiol against MPTP toxicity
    Marc Morissette
    Molecular Endocrinology and Oncology Research Center, Laval University Medical Center, Quebec City, QC, Canada
    Neuropharmacology 52:1509-20. 2007
    ..These results show a greater susceptibility to MPTP toxicity of ERKOalpha mice compared to WT and ERKObeta mice and a role for both ER receptors in striatal DA neuroprotection...