Research Topics

R S Obach

Summary

Affiliation: Pfizer Global Research and Development
Country: USA

Publications

  1. request reprint
    Obach R, Cox L, Tremaine L. Sertraline is metabolized by multiple cytochrome P450 enzymes, monoamine oxidases, and glucuronyl transferases in human: an in vitro study. Drug Metab Dispos. 2005;33:262-70 pubmed
    ..g., CYP2D6, CYP2C19, CYP2C9, UGT1A1) that could profoundly impact the pharmacokinetics of sertraline. ..