Y P Maneuf

Summary

Affiliation: Pfizer Global Research and Development
Country: USA

Publications

  1. ncbi Gabapentin inhibits the substance P-facilitated K(+)-evoked release of [(3)H]glutamate from rat caudial trigeminal nucleus slices
    Y P Maneuf
    Pfizer Global Research and Development, Cambridge Laboratories, Cambridge University Forvie Site, Robinson Way, Cambridge CB2 2QB, UK
    Pain 93:191-6. 2001
  2. ncbi Calcitonin gene-related peptide-mediated increase in K(+)-induced [(3)H]-dopamine release from rat caudal striatal slices
    Y P Maneuf
    Pfizer Global Research and Development, Cambridge Laboratories, University of Cambridge Forvie Site, Robinson Way, Cambridge CB2 2QB, UK
    Neurosci Lett 310:73-6. 2001
  3. ncbi Block by gabapentin of the facilitation of glutamate release from rat trigeminal nucleus following activation of protein kinase C or adenylyl cyclase
    Y P Maneuf
    Pfizer Global R and D, Cambridge Laboratories, University of Cambridge Forvie Site, Robinson Way, Cambridge CB2 2QB
    Br J Pharmacol 134:237-40. 2001

Detail Information

Publications3

  1. ncbi Gabapentin inhibits the substance P-facilitated K(+)-evoked release of [(3)H]glutamate from rat caudial trigeminal nucleus slices
    Y P Maneuf
    Pfizer Global Research and Development, Cambridge Laboratories, Cambridge University Forvie Site, Robinson Way, Cambridge CB2 2QB, UK
    Pain 93:191-6. 2001
    ..In conclusion, we have found and characterized an effect of gabapentin that is of possible mechanistic relevance to the anti-hyperalgesic/allodynic actions of this compound...
  2. ncbi Calcitonin gene-related peptide-mediated increase in K(+)-induced [(3)H]-dopamine release from rat caudal striatal slices
    Y P Maneuf
    Pfizer Global Research and Development, Cambridge Laboratories, University of Cambridge Forvie Site, Robinson Way, Cambridge CB2 2QB, UK
    Neurosci Lett 310:73-6. 2001
    ..This study suggests that the peptide alphaCGRP, modulates dopamine release in the rat caudal striatum probably indirectly via glutamatergic transmission...
  3. ncbi Block by gabapentin of the facilitation of glutamate release from rat trigeminal nucleus following activation of protein kinase C or adenylyl cyclase
    Y P Maneuf
    Pfizer Global R and D, Cambridge Laboratories, University of Cambridge Forvie Site, Robinson Way, Cambridge CB2 2QB
    Br J Pharmacol 134:237-40. 2001
    ..We suggest that these results may be of relevance to the antihyperalgesic properties of gabapentin, in conditions where concomitant release of substance P and CGRP produces activation of PKC and adenylyl cyclase respectively...