Andrew L Hopkins

Summary

Affiliation: Pfizer Global Research and Development
Country: USA

Publications

  1. ncbi request reprint Can we rationally design promiscuous drugs?
    Andrew L Hopkins
    Pfizer Global Research and Development, Sandwich, Kent CT13 9NJ, UK
    Curr Opin Struct Biol 16:127-36. 2006
  2. ncbi request reprint Global mapping of pharmacological space
    Gaia V Paolini
    The Department of Knowledge Discovery, Pfizer Global Research and Development, Sandwich, Kent CT13 9NJ, UK
    Nat Biotechnol 24:805-15. 2006

Collaborators

  • John P Overington
  • Gaia V Paolini
  • Jonathan S Mason
  • Richard H B Shapland
  • Willem P van Hoorn

Detail Information

Publications2

  1. ncbi request reprint Can we rationally design promiscuous drugs?
    Andrew L Hopkins
    Pfizer Global Research and Development, Sandwich, Kent CT13 9NJ, UK
    Curr Opin Struct Biol 16:127-36. 2006
    ..By combining advances in chemoinformatics and structural biology, it might be possible to rationally design the next generation of promiscuous drugs with polypharmacology...
  2. ncbi request reprint Global mapping of pharmacological space
    Gaia V Paolini
    The Department of Knowledge Discovery, Pfizer Global Research and Development, Sandwich, Kent CT13 9NJ, UK
    Nat Biotechnol 24:805-15. 2006
    ..The relationships between proteins, chemical structures and drug-like properties provide a framework for developing a probabilistic approach to drug discovery that can be exploited to increase research productivity...