Research Topics
| Helen DooleySummaryAffiliation: Pfizer Global Research and Development Country: USA Publications
| Collaborators
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Detail Information
Publications
Emergence of the acute-phase protein hemopexin in jawed vertebratesHelen Dooley
Department of Microbiology and Immunology, University of Maryland School of Medicine, 655 West Baltimore Street, Baltimore, MD 21201, USA
Mol Immunol 48:147-52. 2010....
The generation and selection of single-domain, v region libraries from nurse sharksMartin F Flajnik
Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Methods Mol Biol 562:71-82. 2009....
Diversity and repertoire of IgW and IgM VH families in the newborn nurse sharkLynn L Rumfelt
Department of Microbiology and Immunology, University of Miami School of Medicine, Miami, FL 33101, USA
BMC Immunol 5:8. 2004..This nurse shark study examined the IgM and IgW VH repertoire from birth through adult life, and analyzed the phylogenetic relationships of these gene families...
Shark immunity bites back: affinity maturation and memory response in the nurse shark, Ginglymostoma cirratumHelen Dooley
Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, USA
Eur J Immunol 35:936-45. 2005..However, our data suggest that there may also be specific lineages for the different forms (pentameric versus monomeric) of the IgM isotype...
First molecular and biochemical analysis of in vivo affinity maturation in an ectothermic vertebrateHelen Dooley
Department of Microbiology and Immunology, University of Maryland School of Medicine, 655 West Baltimore Street, Baltimore, MD 21201, USA
Proc Natl Acad Sci U S A 103:1846-51. 2006..Because the family clones were all obtained after immunization, they provide insight into the in vivo maturation mechanisms, in general, and for single-domain antibody fragments...
