Joseph C Cappelleri

Summary

Affiliation: Pfizer Global Research and Development
Country: USA

Publications

  1. doi request reprint Psychometric validation of the physician global assessment scale for assessing severity of psoriasis disease activity
    J C Cappelleri
    Pfizer Inc, 445 Eastern Point Road, MS 8260 2502, Groton, CT, 06340, USA
    Qual Life Res 22:2489-99. 2013
  2. pmc The association of sleep difficulties with health-related quality of life among patients with fibromyalgia
    Jan Samuel Wagner
    Health Outcomes Practice, Kantar Health, 11 Madison Avenue, 12th Floor, New York, NY 10010, USA
    BMC Musculoskelet Disord 13:199. 2012
  3. doi request reprint Estimating the economic benefits of positive shifts in fibromyalgia severity: an exploratory analysis based on modeling of clinical trial data of pregabalin
    Joseph C Cappelleri
    Pfizer Inc, Groton, CT, USA
    J Med Econ 16:55-61. 2013
  4. pmc Assessment of measurement properties of peak VO(2) in children with pulmonary arterial hypertension
    Joseph C Cappelleri
    Department of Statistics, Pfizer Inc, Groton, CT, USA
    BMC Pulm Med 12:54. 2012
  5. pmc Relationships between changes in pain severity and other patient-reported outcomes: an analysis in patients with posttraumatic peripheral neuropathic pain
    Robert van Seventer
    Pain Clinic, Amphia Hospital, Breda, The Netherlands
    Health Qual Life Outcomes 9:17. 2011
  6. pmc Dupuytren's contracture: a retrospective database analysis to determine hospitalizations in the Netherlands
    Jetty A Overbeek
    PHARMO Institute, Utrecht, The Netherlands
    BMC Res Notes 4:402. 2011
  7. pmc Identification of symptom and functional domains that fibromyalgia patients would like to see improved: a cluster analysis
    Robert M Bennett
    Oregon Health and Science University, Portland, Oregon, USA
    BMC Musculoskelet Disord 11:134. 2010
  8. doi request reprint Psychometric analysis of the Three-Factor Eating Questionnaire-R21: results from a large diverse sample of obese and non-obese participants
    J C Cappelleri
    Pfizer Inc, Global Research and Development, New London, CT 06320, USA
    Int J Obes (Lond) 33:611-20. 2009
  9. ncbi request reprint Association between the Erectile Dysfunction Inventory of Treatment Satisfaction and the Self-Esteem and Relationship Questionnaire following treatment with sildenafil citrate for men with erectile dysfunction
    Joseph C Cappelleri
    Pfizer Inc, Global Research and Development, Groton, CT 06340 8030, USA
    Value Health 8:S54-60. 2005
  10. ncbi request reprint Comparison between sildenafil-treated subjects with erectile dysfunction and control subjects on the Self-Esteem And Relationship questionnaire
    Joseph C Cappelleri
    Pfizer Inc, Global Research and Development, Groton, CT 06340, USA
    J Sex Med 3:274-82. 2006

Collaborators

Detail Information

Publications67

  1. doi request reprint Psychometric validation of the physician global assessment scale for assessing severity of psoriasis disease activity
    J C Cappelleri
    Pfizer Inc, 445 Eastern Point Road, MS 8260 2502, Groton, CT, 06340, USA
    Qual Life Res 22:2489-99. 2013
    ..The Physician Global Assessment (PGA) is a key measure of psoriasis frequently used in clinical trials. A psychometric validation of a three-item (erythema, induration, and scaling) PGA scale was performed using Phase 2 data...
  2. pmc The association of sleep difficulties with health-related quality of life among patients with fibromyalgia
    Jan Samuel Wagner
    Health Outcomes Practice, Kantar Health, 11 Madison Avenue, 12th Floor, New York, NY 10010, USA
    BMC Musculoskelet Disord 13:199. 2012
    ..The aim of the current study was to assess the burden of sleep difficulty symptoms on HRQoL among patients with FM...
  3. doi request reprint Estimating the economic benefits of positive shifts in fibromyalgia severity: an exploratory analysis based on modeling of clinical trial data of pregabalin
    Joseph C Cappelleri
    Pfizer Inc, Groton, CT, USA
    J Med Econ 16:55-61. 2013
    ..To estimate the annualized differences in direct medical and indirect costs associated with improvement in fibromyalgia (FM) severity among pregabalin-treated patients...
  4. pmc Assessment of measurement properties of peak VO(2) in children with pulmonary arterial hypertension
    Joseph C Cappelleri
    Department of Statistics, Pfizer Inc, Groton, CT, USA
    BMC Pulm Med 12:54. 2012
    ..Our working hypothesis was that, as with other populations, percentage changes in peak VO2 in pediatric patients with PAH are reliable and are associated with changes in other clinical endpoints...
  5. pmc Relationships between changes in pain severity and other patient-reported outcomes: an analysis in patients with posttraumatic peripheral neuropathic pain
    Robert van Seventer
    Pain Clinic, Amphia Hospital, Breda, The Netherlands
    Health Qual Life Outcomes 9:17. 2011
    ....
  6. pmc Dupuytren's contracture: a retrospective database analysis to determine hospitalizations in the Netherlands
    Jetty A Overbeek
    PHARMO Institute, Utrecht, The Netherlands
    BMC Res Notes 4:402. 2011
    ..abstract:..
  7. pmc Identification of symptom and functional domains that fibromyalgia patients would like to see improved: a cluster analysis
    Robert M Bennett
    Oregon Health and Science University, Portland, Oregon, USA
    BMC Musculoskelet Disord 11:134. 2010
    ..The purpose of this study was to determine whether some of the clinical features of fibromyalgia (FM) that patients would like to see improved aggregate into definable clusters...
  8. doi request reprint Psychometric analysis of the Three-Factor Eating Questionnaire-R21: results from a large diverse sample of obese and non-obese participants
    J C Cappelleri
    Pfizer Inc, Global Research and Development, New London, CT 06320, USA
    Int J Obes (Lond) 33:611-20. 2009
    ..The 21-item Three-Factor Eating Questionnaire (TFEQ-R21) is a scale that measures three domains of eating behavior: cognitive restraint (CR), uncontrolled eating (UE) and emotional eating (EE)...
  9. ncbi request reprint Association between the Erectile Dysfunction Inventory of Treatment Satisfaction and the Self-Esteem and Relationship Questionnaire following treatment with sildenafil citrate for men with erectile dysfunction
    Joseph C Cappelleri
    Pfizer Inc, Global Research and Development, Groton, CT 06340 8030, USA
    Value Health 8:S54-60. 2005
    ....
  10. ncbi request reprint Comparison between sildenafil-treated subjects with erectile dysfunction and control subjects on the Self-Esteem And Relationship questionnaire
    Joseph C Cappelleri
    Pfizer Inc, Global Research and Development, Groton, CT 06340, USA
    J Sex Med 3:274-82. 2006
    ..Erectile dysfunction (ED) can negatively impact psychosocial measures of a patient's sexual life...
  11. ncbi request reprint Confirmatory factor analyses and reliability of the modified cigarette evaluation questionnaire
    Joseph C Cappelleri
    Pfizer Global Research and Development, Eastern Point Road, MS 8260 2222, Groton, CT 06340, USA
    Addict Behav 32:912-23. 2007
    ....
  12. ncbi request reprint Multivariate framework of the Brief Questionnaire of Smoking Urges
    Joseph C Cappelleri
    Pfizer Inc, Global Research and Development, Eastern Point Road, MS 8260 2222 Groton, CT 06340, USA
    Drug Alcohol Depend 90:234-42. 2007
    ..75) on the Total Craving Score and on Factors 1 and 2. This research supports the validity and reliability of the instrument and confirms the proposed two-dimensional structure of self-reported craving as measured by the QSU-Brief...
  13. ncbi request reprint Analysis of single items on the Self-Esteem and Relationship questionnaire in men treated with sildenafil citrate for erectile dysfunction: results of two double-blind, placebo-controlled trials
    Joseph C Cappelleri
    Pfizer Inc, Global Research and Development, Groton, CT 06340, USA
    BJU Int 101:861-6. 2008
    ....
  14. ncbi request reprint Clinically meaningful improvement on the Self-Esteem And Relationship questionnaire in men with erectile dysfunction
    Joseph C Cappelleri
    Pfizer Inc, Global Research and Development, MS 8260 2222, Eastern Point Road, Groton, CT 06340 8030, USA
    Qual Life Res 16:1203-10. 2007
    ..To estimate the minimal clinically meaningful improvement (MCMI) on the Self-Esteem And Relationship (SEAR) questionnaire...
  15. doi request reprint An assessment of patient-reported outcomes for men with erectile dysfunction: Pfizer's perspective
    J C Cappelleri
    Pfizer Inc, Global Research and Development, New London, CT, USA
    Int J Impot Res 20:343-57. 2008
    ..Each of these instruments represents a significant contribution to sexual medicine research and, when used judiciously and appropriately, can help to provide optimal patient care and management...
  16. pmc Development and validation of the WEll-being and Satisfaction of CAREgivers of Children with Diabetes Questionnaire (WE-CARE)
    Joseph C Cappelleri
    Pfizer Global Research and Development, Groton, CT, USA
    Health Qual Life Outcomes 6:3. 2008
    ....
  17. pmc Psychometric properties of a single-item scale to assess sleep quality among individuals with fibromyalgia
    Joseph C Cappelleri
    Pfizer Inc, Global Research and Development, New London, Connecticut 06320, USA
    Health Qual Life Outcomes 7:54. 2009
    ..Sleep disturbances are a common and bothersome symptom of fibromyalgia (FM). This study reports psychometric properties of a single-item scale to assess sleep quality among individuals with FM...
  18. doi request reprint Pain responder analysis: use of area under the curve to enhance interpretation of clinical trial results
    Joseph C Cappelleri
    Pfizer Inc, New London, Connecticut 06320, USA
    Pain Pract 9:348-53. 2009
    ..7% (450 mg/day), and 12.5% (600 mg/day) more than placebo responders. This novel approach demonstrates that responder profiles can provide an enhanced interpretation of pain outcomes for patient care and symptom management...
  19. ncbi request reprint Revealing the multidimensional framework of the Minnesota nicotine withdrawal scale
    Joseph C Cappelleri
    Pfizer Inc, Global Research and Development, Groton, CT 06340, USA
    Curr Med Res Opin 21:749-60. 2005
    ..No psychometric analyses of this version have been published. The objectives of this investigation were to perform a factor analysis and to further assess the psychometric properties of the MNWS...
  20. ncbi request reprint The Sexual Health Inventory for Men (SHIM): a 5-year review of research and clinical experience
    J C Cappelleri
    Pfizer Inc, Global Research and Development, Groton, CT 06340 8030, USA
    Int J Impot Res 17:307-19. 2005
    ..These scientific contributions are likely to remain influential in coming years...
  21. doi request reprint Analysis of dyadic data: a guideline applied to erectile dysfunction
    Joseph C Cappelleri
    Pfizer Inc, Global Research and Development, New London, CT 06320, USA
    J Eval Clin Pract 16:1340-4. 2010
    ..Nonetheless, such data has been often analysed by examining individuals in isolation, which falls short of capturing their truly interpersonal and non-independent nature...
  22. doi request reprint Measurement properties of the Medical Outcomes Study Sleep Scale in patients with fibromyalgia
    Joseph C Cappelleri
    Pfizer Inc, Global Research and Development, 50 Pequot Avenue, New London, CT 06320, USA
    Sleep Med 10:766-70. 2009
    ..Sleep problems are a common symptom of fibromyalgia (FM). The objective of this study was to evaluate the Medical Outcomes Study (MOS) Sleep Scale as a measure of FM-related sleep problems...
  23. doi request reprint Relationship between patient-reported disease severity and other clinical outcomes in osteoarthritis: a European perspective
    Andrew G Bushmakin
    Pfizer Inc, 235 East 42nd Street, New York, NY 10017, USA
    J Med Econ 14:381-9. 2011
    ..To determine how patient-rated osteoarthritis (OA) severity correlates with other patient-reported and clinical outcomes in the European clinical setting...
  24. doi request reprint Scoring correspondence in outcomes related to erectile dysfunction treatment on a 4-point scale (SCORE-4)
    Joseph C Cappelleri
    Pfizer Inc, Global Research and Development, New London, CT 06320, USA
    J Sex Med 6:809-19. 2009
    ..The Erection Hardness Score (EHS), a validated single-item patient-reported outcome (PRO), may provide a simple method to capture erectile dysfunction (ED) symptoms and to monitor treatment outcome...
  25. doi request reprint Baseline patient-reported kidney cancer-specific symptoms as an indicator for median survival in sorafenib-refractory metastatic renal cell carcinoma
    Peter C Trask
    Pfizer Oncology, Global Outcomes Research, Pfizer Inc, MS 6025 A3221, 50 Pequot Ave, New London, CT 06320, USA
    J Cancer Surviv 5:255-62. 2011
    ....
  26. doi request reprint Applying area-under-the-curve analysis to enhance interpretation of response profiles: an application to sleep quality scores in patients with fibromyalgia
    Andrew G Bushmakin
    Pfizer Inc, Global Research and Development, 50 Pequot Ave, New London, CT 06320, USA
    Qual Life Res 20:491-8. 2011
    ..To introduce an application of area-under-the-curve (AUC) that can enrich interpretation of response analysis and illustrate this method on sleep quality scores in patients with fibromyalgia...
  27. doi request reprint Cumulative response curves to enhance interpretation of treatment differences on the Self-Esteem And Relationship questionnaire for men with erectile dysfunction
    Joseph C Cappelleri
    Pfizer Inc, Groton, CT 06340, USA zer com
    BJU Int 111:E115-20. 2013
    ..CRCs for PROs in urology can provide a clear, transparent and meaningful visual depiction of efficacy data that can supplement and complement other analyses...
  28. doi request reprint Using the Rasch model to validate and enhance the interpretation of the Functional Assessment of Cancer Therapy-Kidney Symptom Index--Disease-Related Symptoms scale
    Xuemei Luo
    Global Outcomes Research, Pfizer Inc, New London, CT 06320, USA
    Value Health 12:580-6. 2009
    ..The Rasch rating scale, a one-parameter logistic item response model, may enhance FKSI-DRS interpretation and validate its measurement properties...
  29. doi request reprint Clinical evaluation of the Daily Assessment of Symptoms-Anxiety (DAS-A): a new instrument to assess the onset of symptomatic improvement in generalized anxiety disorder
    Douglas E Feltner
    Pfizer Global Research and Development, 50 Pequot Avenue, New London, CT 06320, USA
    CNS Neurosci Ther 15:12-8. 2009
    ..Rapid onset of symptomatic improvement is a desirable characteristic of new generalized anxiety disorder (GAD) treatments. A validated rating scale is needed to assess GAD symptoms during the first days of treatment...
  30. doi request reprint Two confidence interval approaches on the dependability coefficient in a two-factor crossed design
    Naitee Ting
    Pfizer Inc, Global Research and Development, New London, Connecticut, USA
    J Biopharm Stat 19:610-24. 2009
    ..Both methods generally meet at least the nominal coverage. Both methods are illustrated with examples...
  31. pmc Relationship between patient-reported disease severity in osteoarthritis and self-reported pain, function and work productivity
    Alesia B Sadosky
    Pfizer Inc, Global Health Economics and Outcomes Research, New York, NY 10017, USA
    Arthritis Res Ther 12:R162. 2010
    ..The objective of this study was to determine how patient-reported OA severity correlates with patient-reported outcomes including pain, function and productivity...
  32. ncbi request reprint Development and evaluation of the Daily Assessment of Symptoms - Anxiety (DAS-A) scale to evaluate onset of symptom relief in patients with generalized anxiety disorder
    Robert J Morlock
    Pfizer Inc, Global Research and Development, Ann Arbor, MI, USA
    J Psychiatr Res 42:1024-36. 2008
    ....
  33. doi request reprint Estimating a minimally important difference in pulmonary arterial hypertension following treatment with sildenafil
    Claire Gilbert
    PGRD, Pfizer Ltd, Sandwich, UK
    Chest 135:137-42. 2009
    ..These analyses were undertaken to help define a minimally important difference (MID) in exercise capacity, measured by the 6-min walk distance (6MWD), and HRQoL, measured by the Short Form-36 (SF-36) questionnaire in patients with PAH...
  34. ncbi request reprint Patient satisfaction and glycemic control after 1 year with inhaled insulin (Exubera) in patients with type 1 or type 2 diabetes
    Julio Rosenstock
    Dallas Diabetes and Endocrine Center, Dallas, Texas, USA
    Diabetes Care 27:1318-23. 2004
    ....
  35. ncbi request reprint Role of pharmacoepidemiology in evaluating prescription drug safety in pediatrics
    Xuemei Luo
    Duke University Health System, Durham, NC, USA
    Curr Med Res Opin 23:2607-15. 2007
    ..But this methodology has not been widely utilized to assess drug safety in pediatrics for children aged between 0 and 18 years...
  36. ncbi request reprint Improved detection of differential information-processing speed deficits between two disease-course types of multiple sclerosis
    P J Snyder
    Department of Clinical Research, Pfizer Global Research and Development, Groton, Connecticut 06340, USA
    Neuropsychology 15:617-25. 2001
    ..Mean dyad scores < 4.13 classified patients as having SPMS with 73% accuracy (sensitivity), whereas scores > or = 4.13 classified patients as having RRMS with 80% accuracy (specificity)...
  37. ncbi request reprint Relationship between patient self-assessment of erectile dysfunction and the sexual health inventory for men
    J C Cappelleri
    Global Research and Development, Pfizer Inc, Groton, Connecticut 06340, USA
    Clin Ther 23:1707-19. 2001
    ..However, the SHIM has not been compared with patient self-assessment of ED...
  38. ncbi request reprint Treatment satisfaction with inhaled insulin in patients with type 1 diabetes: a randomized controlled trial
    R A Gerber
    Pfizer Inc, Global Research and Development, Eastern Point Road, Groton, CT 06340, USA
    Diabetes Care 24:1556-9. 2001
    ..Our objective was to compare patient satisfaction between inhaled insulin and subcutaneous insulin...
  39. doi request reprint Evaluating the Power of Food Scale in obese subjects and a general sample of individuals: development and measurement properties
    J C Cappelleri
    Global Research and Development, Pfizer Inc, New London, CT 06320, USA
    Int J Obes (Lond) 33:913-22. 2009
    ..The Power of Food Scale (PFS) was developed to assess the psychological impact of today's food-abundant environments...
  40. ncbi request reprint Development and validation of the Self-Esteem And Relationship (SEAR) questionnaire in erectile dysfunction
    J C Cappelleri
    Pfizer Inc Global Research and Development, Groton, CT 06340, USA
    Int J Impot Res 16:30-8. 2004
    ..0001). The SEAR questionnaire possesses strong psychometric properties that support its validity and reliability for measuring sexual relationship, confidence, and particularly self-esteem...
  41. ncbi request reprint Development and factor analysis of a questionnaire to measure patient satisfaction with injected and inhaled insulin for type 1 diabetes
    J C Cappelleri
    Pfizer Inc, Global Research and Development, Groton, Connecticut 06340, USA
    Diabetes Care 23:1799-803. 2000
    ....
  42. doi request reprint Impact of a step-therapy protocol for pregabalin on healthcare utilization and expenditures in a commercial population
    Margarita Udall
    Pfizer Inc, New York, NY, USA
    J Med Econ 16:784-92. 2013
    ....
  43. ncbi request reprint A new approach for interval estimation and hypothesis testing of a certain intraclass correlation coefficient: the generalized variable method
    Lili Tian
    Department of Statistics, Biostatistics Division, University of Florida, Gainesville 32610, USA
    Stat Med 23:2125-35. 2004
    ..The fact that the GCI approach is suitable for confidence interval estimation and obtaining P-values makes the GCI approach a suitable candidate for making inference about interrater reliability...
  44. ncbi request reprint A modified large-sample approach to approximate interval estimation for a particular intraclass correlation coefficient
    Joseph C Cappelleri
    Pfizer Inc, Global Research and Development, Groton, Connecticut 06340, USA
    Stat Med 22:1861-77. 2003
    ..Overall, the modified large-sample approach provides the most satisfactory performance of the three methods...
  45. doi request reprint Sexual function questionnaire: further refinement and validation
    Tara Symonds
    PRO Centre of Excellence, PCBU, Pfizer Ltd, Walton Oaks, Surrey, UK
    J Sex Med 9:2609-16. 2012
    ..The Sexual Function Questionnaire (SFQ) is a self-report outcome measure of female sexual function. It has recently been refined to create a 28-item version (SFQ28) including the addition of a new arousal-cognitive domain...
  46. doi request reprint Health-related quality of life during treatment for renal cell carcinoma: results from a phase II study of axitinib
    Peter C Trask
    Global Outcomes Research, Pfizer Inc, New London, CT 06320, USA
    Acta Oncol 47:843-51. 2008
    ..This study examined the HRQOL of patients with metastatic RCC treated with axitinib, a new targeted therapy that affects the vessels supplying blood to the tumor...
  47. ncbi request reprint Hierarchical construct validity of the treatment satisfaction questionnaire for medication (TSQM version II) among outpatient pharmacy consumers
    Mark J Atkinson
    Worldwide Outcomes Research, La Jolla Laboratories, Pfizer Inc, San Diego, CA 92121 1111, USA
    Value Health 8:S9-S24. 2005
    ..II) using structural equation modeling (SEM); and 2) to assess its concurrent validity using medication adherence criteria...
  48. ncbi request reprint Validation of the behavioural activity rating scale (BARS): a novel measure of activity in agitated patients
    R H Swift
    Pfizer Inc, Global Research and Development, Eastern Point Road, Groton, CT 06340, USA
    J Psychiatr Res 36:87-95. 2002
    ..Virtually perfect inter- and intra-rater reliability was achieved. Study 1 produced similar results. BARS showed psychometrically valid properties for measurement of behavioral activity in acutely agitated patients with psychosis...
  49. doi request reprint Using the probability-probability plot and index to augment interpretation of treatment effect for patient-reported outcome measures
    Joseph C Cappelleri
    Pfizer Inc, 445 Eastern Point Road, MS 8260 2502, Groton, CT 06340, USA
    Expert Rev Pharmacoecon Outcomes Res 13:707-13. 2013
    ..This measure, which complements other metrics of treatment effect, captures full information by integrating across all percentiles and thus accurately summarizes and augments the interpretation of treatment effect. ..
  50. ncbi request reprint Treatment satisfaction in type 2 diabetes: a comparison between an inhaled insulin regimen and a subcutaneous insulin regimen
    Joseph C Cappelleri
    Pfizer Inc, Global Research and Development, Groton, Connecticut 06340, USA
    Clin Ther 24:552-64. 2002
    ..It is unknown whether inhalation delivery of insulin improves patient satisfaction...
  51. doi request reprint Understanding heterogeneity in meta-analysis: the role of meta-regression
    W L Baker
    University of Connecticut, Storrs, CT, USA
    Int J Clin Pract 63:1426-34. 2009
    ..However, many clinicians and decision-makers may be unfamiliar with the underlying principles and assumptions made within meta-regression leading to incorrect interpretation of their results...
  52. ncbi request reprint Treatment responsiveness of the Self-Esteem And Relationship questionnaire in erectile dysfunction
    Stanley E Althof
    Case Western Reserve University, Beachwood, Ohio 44122, USA
    Urology 61:888-92. 2003
    ..To determine the treatment responsiveness of the disease-specific Self-Esteem And Relationship (SEAR) questionnaire in erectile dysfunction...
  53. ncbi request reprint Validation of the erection hardness score
    John P Mulhall
    Weill Medical College of Cornell University and Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Sex Med 4:1626-34. 2007
    ..Erection hardness is a fundamental component of erectile function, and is a very specific and easily monitored outcome. The Erection Hardness Score (EHS) is a single-item, patient-reported outcome (PRO) for scoring erection hardness...
  54. ncbi request reprint Effect of varenicline and bupropion SR on craving, nicotine withdrawal symptoms, and rewarding effects of smoking during a quit attempt
    Robert West
    Cancer Research UK Health Behaviour Unit, Department of Epidemiology and Public Health, University College London, Brook House, London, UK
    Psychopharmacology (Berl) 197:371-7. 2008
    ....
  55. doi request reprint Evaluating the sexual experience in men: validation of the sexual experience questionnaire
    John P Mulhall
    Department of Urology, Weill Medical College of Cornell University, New York, NY, USA
    J Sex Med 5:365-76. 2008
    ..The absence of a single brief measure that assesses function and health-related quality of life (HRQoL) hinders evaluation of the sexual experience in men with erectile dysfunction (ED)...
  56. ncbi request reprint Regulatory issues for health-related quality of life--PhRMA Health Outcomes Committee workshop, 1999
    Nancy C Santanello
    Merck Research Laboratories, PO Box 4, BL 1 7, West Point, PA 19486, USA
    Value Health 5:14-25. 2002
    ..Health-related quality-of-life measures are included in clinical trials of drug treatment to assess the impact of therapy on the patient's functioning. HRQL guidance could allow for use of this data in drug labeling and promotion...
  57. doi request reprint Quality of life in patients with metastatic renal cell carcinoma treated with sunitinib or interferon alfa: results from a phase III randomized trial
    David Cella
    Center on Outcomes, Research and Education, Evanston Northwestern Healthcare and Northwestern University Feinberg School of Medicine, 1001 University Place, Evanston, IL 60201, USA
    J Clin Oncol 26:3763-9. 2008
    ..001; objective response rate, 31% v 6%, respectively; P < .001). We report health-related quality-of-life (QOL) results from this trial...
  58. ncbi request reprint A systematic review on the application of pharmacoepidemiology in assessing prescription drug-related adverse events in pediatrics
    Xuemei Luo
    Center for Patient Safety and Clinical Quality, Duke University Health System, Durham, NC, USA
    Curr Med Res Opin 23:1015-24. 2007
    ....
  59. ncbi request reprint Assessing the clinical significance of single items relative to summated scores
    Jeff A Sloan
    Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA
    Mayo Clin Proc 77:479-87. 2002
    ..The 2 types of indices are not mutually exclusive and can be used together in a single research study or in the clinical setting...
  60. ncbi request reprint Impact of erectile dysfunction on confidence, self-esteem and relationship satisfaction after 9 months of sildenafil citrate treatment
    Stanley E Althof
    Center for Marital and Sexual Health of South Florida, West Palm Beach, Florida 33401, USA
    J Urol 176:2132-7. 2006
    ..We investigated long-term improvement, and correlations between improved erectile function and confidence, self-esteem and sexual relationship satisfaction in men with erectile dysfunction...
  61. pmc Self-esteem, confidence, and relationships in men treated with sildenafil citrate for erectile dysfunction: results of two double-blind, placebo-controlled trials
    Stanley E Althof
    Case Western Reserve University, Cleveland, OH, USA
    J Gen Intern Med 21:1069-74. 2006
    ..Men with erectile dysfunction (ED) often have low self-esteem, confidence, and sexual relationship satisfaction...
  62. ncbi request reprint Sildenafil citrate improves self-esteem, confidence, and relationships in men with erectile dysfunction: Results from an international, multi-center, double-blind, placebo-controlled trial
    Stanley E Althof
    Case Western Reserve University Medical School, West Palm Beach, FL33401, USA
    J Sex Med 3:521-9. 2006
    ..Erectile dysfunction (ED) can significantly impact a man's relationships and well-being...
  63. ncbi request reprint Self-esteem, confidence and relationship satisfaction of men with erectile dysfunction treated with sildenafil citrate: a multicenter, randomized, parallel group, double-blind, placebo controlled study in the United States
    MICHAEL P O'LEARY
    Department of Surgery, Harvard Medical School, and Division of Urology, Brigham and Women s Hospital, Boston, Massachusetts 02115 6105, USA
    J Urol 175:1058-62. 2006
    ....
  64. ncbi request reprint Applying quality-of-life data formally and systematically into clinical practice
    Marlene H Frost
    Women s Cancer Program, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Mayo Clin Proc 82:1214-28. 2007
    ..However, the work done to date requires continued development. Continued research is needed that provides information about benefits and addresses limitations of current approaches...
  65. ncbi request reprint Applying the law of iterated logarithm to control type I error in cumulative meta-analysis of binary outcomes
    Mingxiu Hu
    Millennium Pharmaceuticals, 35 Landsdowne Street, Cambridge, MA 02139, USA
    Clin Trials 4:329-40. 2007
    ..Applying the law of iterated logarithm to cumulative meta-analysis of a continuous endpoint. Statistica Sinica 2003; 13: 1135-45) proposed an approach based on the law of iterated logarithm (LIL) to this problem for the continuous case...
  66. ncbi request reprint Bayesian methods to improve sample size approximations
    Christopher H Schmid
    Institute for Clinical Research and Health Policy Studies, Tufts New England Medical Center, Boston, Massachusetts 02111, USA
    Methods Enzymol 383:406-27. 2004
  67. ncbi request reprint Patient-reported outcomes: conceptual issues
    Margaret L Rothman
    Johnson and Johnson Pharmaceutical Services LLC, Raritan, NJ, USA
    Value Health 10:S66-75. 2007
    ....