Alexander A Alex
Affiliation: Pfizer Global Research and Development
- Fragment-based drug discovery: what has it achieved so far?Alexander A Alex
Pfizer Global Research and Development, Sandwich Laboratories, Ramsgate Road, Sandwich, Kent CT13 9NJ, UK
Curr Top Med Chem 7:1544-67. 2007..However, due to the time scales of drug discovery and development it is likely that over the next few years the number of such examples will increase significantly...
- Development of a combined protein and pharmacophore model for cytochrome P450 2C9Marcel J de Groot
Department of Molecular Informatics, Structure and Design, Pfizer Global Research and Development, Sandwich Laboratories, Ramsgate Road, Sandwich, Kent CT13 9NJ, U K
J Med Chem 45:1983-93. 2002..The model has also been successful in explaining the differences in substrate specificity between CYP2C9 and CYP2C19...