Eric C Petrie
- Preclinical evidence of Alzheimer changes: convergent cerebrospinal fluid biomarker and fluorodeoxyglucose positron emission tomography findingsEric C Petrie
Mail Code S 182 GRECC, Veterans Affairs Puget Sound Health Care System, 1660 S Columbian Way, Seattle, WA 98108, USA
Arch Neurol 66:632-7. 2009....
- Apolipoprotein E highly correlates with AbetaPP- and tau-related markers in human cerebrospinal fluidSimona Vuletic
Northwest Lipid Metabolism and Diabetes Research Laboratories, University of Washington School of Medicine, Seattle, WA 98109, USA
J Alzheimers Dis 15:409-17. 2008..Our data suggest that there is a significant physiological link between apoE and AbetaPP, as well as between apoE and tau in neurologically healthy, cognitively intact individuals...
- Effect of statins on Alzheimer's disease biomarkers in cerebrospinal fluidRobert G Riekse
Department of Medicine, Division of Geriatric Medicine, University of Washington School of Medicine, and VA Puget Sound Health Care System, Seattle, WA 98108, USA
J Alzheimers Dis 10:399-406. 2006..Putative neuroprotective effects of statins may vary in relation to their ability to penetrate into the central nervous system (CNS)...
- Cerebrospinal fluid norepinephrine and cognition in subjects across the adult age spanLucy Y Wang
Mental Illness Research and Education Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA
Neurobiol Aging 34:2287-92. 2013..0, SE 2.2, p = 0.024; Stroop Word-Color Interference task: regression coefficient 6.1, SE 2.0, p = 0.003). Findings are consistent with the earlier literature relating excess noradrenergic activity with cognitive impairment. ..
- Loss of olfactory tract integrity affects cortical metabolism in the brain and olfactory regions in aging and mild cognitive impairmentDonna J Cross
Department of Radiology, University of Washington, Seattle, Washington 98195 7115, USA
J Nucl Med 54:1278-84. 2013..We hypothesized that MCI subjects would show loss of olfactory tract integrity and may have altered associations with glucose metabolism...
- Cerebrocerebellar hypometabolism associated with repetitive blast exposure mild traumatic brain injury in 12 Iraq war Veterans with persistent post-concussive symptomsElaine R Peskind
Northwest Network Mental Illness, Research, Education, and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA
Neuroimage 54:S76-82. 2011..Given the potential public health implications of these findings, further investigation of brain function in these Veterans appears warranted...
- Prazosin reduces nightmares in combat veterans with posttraumatic stress disorderMurray A Raskind
Northwest Network Mental Illness Research, Education and Clinical Center, VA Puget Sound Health Care System and University of Washington, Seattle 98108, USA
J Clin Psychiatry 63:565-8. 2002..Preclinical and clinical observations suggest that the centrally active alpha1-adrenergic antagonist prazosin might alleviate trauma content nightmares and other symptoms in combat veterans with chronic posttraumatic stress disorder (PTSD)...
- Blast exposure causes early and persistent aberrant phospho- and cleaved-tau expression in a murine model of mild blast-induced traumatic brain injuryBertrand R Huber
Northwest Network Mental Illness, Research, Education, and Clinical Center MIRECC, Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA
J Alzheimers Dis 37:309-23. 2013..These findings may have important implications for efforts to prevent blast-induced insults to the brain from progressing into long-term neurodegenerative disease processes. ..
- Lewy body pathology in late-onset familial Alzheimer's disease: a clinicopathological case seriesDebby W Tsuang
Mental Illness Research, Education, and Clinical Centers, Veteran Affairs Puget Sound Health Care System, Seattle, WA 98108, USA
J Alzheimers Dis 9:235-42. 2006..Lewy body pathology (LBP) is a common finding in Alzheimer's disease (AD), but the pathophysiology for this coexistent pathology remains unclear...
- Salivary cortisol and memory function in human agingGe Li
Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98195, USA
Neurobiol Aging 27:1705-14. 2006..Previous studies have suggested that elevated glucocorticoid concentrations alter hippocampal neuronal morphology, inhibit neurogenesis, and impair cognition...
- Reduction of nightmares and other PTSD symptoms in combat veterans by prazosin: a placebo-controlled studyMurray A Raskind
Northwest Network VISN 20 Mental Illness Research, Eduation, and Clinical Center, VA Puget Sound Healthcare System, Seattle, USA
Am J Psychiatry 160:371-3. 2003..Prazosin is a centrally active alpha(1) adrenergic antagonist. The authors' goal was to evaluate prazosin efficacy for nightmares, sleep disturbance, and overall posttraumatic stress disorder (PTSD) in combat veterans...
- Neuroimaging in dementia with Lewy bodies: metabolism, neurochemistry, and morphologySatoshi Minoshima
Departments of Radiology, University of Washington School of Medicine, Seattle, Washington 98195 6004, USA
J Geriatr Psychiatry Neurol 15:200-9. 2002....