Renee P Stokowski
Affiliation: Perlegen Sciences
- Assessment of clinical validity of a breast cancer risk model combining genetic and clinical informationMatthew E Mealiffe
Perlegen Sciences, Inc, Mountain View, CA, USA
J Natl Cancer Inst 102:1618-27. 2010..However, it remains unclear how to effectively integrate clinical and genetic risk factors for risk assessment...
- A genomewide association study of skin pigmentation in a South Asian populationRenee P Stokowski
Perlegen Sciences, Mountain View, CA 94043, USA
Am J Hum Genet 81:1119-32. 2007..Our study is the first to interrogate polymorphisms across the genome, to find genetic determinants of the natural variation of skin pigmentation within a human population...
- Variant in PNPLA3 is associated with alcoholic liver diseaseChao Tian
Perlegen Sciences, Mountain View, California, USA
Nat Genet 42:21-3. 2010..We found that rs738409 in PNPLA3 is strongly associated with alcoholic liver disease and clinically evident alcoholic cirrhosis (unadjusted OR= 2.25, P=1.7 x 10(-10); ancestry-adjusted OR=1.79, P=1.9 x 10(-5))...
- Matching strategies for genetic association studies in structured populationsDavid A Hinds
Perlegen Sciences, Mountain View, CA, 94043, USA
Am J Hum Genet 74:317-25. 2004..Results for an admixed population and a phenotype strongly confounded with ancestry show that these simple matching strategies can effectively mitigate the impact of population stratification...