- Applying mathematical tools to accelerate vaccine development: modeling Shigella immune dynamicsCourtney L Davis
Natural Science Division, Pepperdine University, Malibu, California, United States of America
PLoS ONE 8:e59465. 2013..It introduces mathematical models to the Shigella vaccine development effort and lays a foundation for joint theoretical/experimental/clinical approaches to Shigella vaccine design...
- Mathematical models of memory CD8+ T-cell repertoire dynamics in response to viral infectionsCourtney L Davis
Natural Science Division, Pepperdine University, Malibu, CA, USA
Bull Math Biol 75:491-522. 2013..We find that early memory attrition does not permanently alter the repertoire composition, while infections that spark substantial new memory generation drastically shift the repertoire and hasten the decline of existing immunity...