Affiliation: Pennsylvania State University
- Acute effects of moderate intensity resistance exercise on bone cell activityT J Whipple
Department of Kinesiology and Noll Laboratory, Pennsylvania State University, Hershey, PA, USA
Int J Sports Med 25:496-501. 2004..Further work is needed to determine if long-term benefits to bone strength follow with persistent training...
- Magnitude of daily energy deficit predicts frequency but not severity of menstrual disturbances associated with exercise and caloric restrictionNancy I Williams
Women s Health and Exercise Laboratory and the Department of Kinesiology, Pennsylvania State University, University Park, Pennsylvania and
Am J Physiol Endocrinol Metab 308:E29-39. 2015....
- Decreased luteinizing hormone pulse frequency is associated with elevated 24-hour ghrelin after calorie restriction and exercise in premenopausal womenJennifer L Scheid
Women s Health and Exercise Laboratory, Noll Laboratory, Dept of Kinesiology, Penn State University, University Park, PA 16802, USA
Am J Physiol Endocrinol Metab 304:E109-16. 2013..704, P = 0.001). Elevated total ghrelin concentrations are associated with the suppression of LH pulsatility in premenopausal women and may play a role in the suppression of reproductive function following weight loss...
- Estrogen and progesterone exposure is reduced in response to energy deficiency in women aged 25-40 yearsN I Williams
Department of Kinesiology, Women s Health and Exercise Laboratories, Penn State University, Noll Laboratory, University Park, PA 16802, USA
Hum Reprod 25:2328-39. 2010..This study aimed to test the hypothesis that moderate exercise training combined with caloric restriction would produce significant menstrual disturbances and alterations in ovarian steroids in premenopausal women...
- Effects of short-term strenuous endurance exercise upon corpus luteum functionN I Williams
Department of Health Sciences, Sargent College, Boston University, MA, USA
Med Sci Sports Exerc 31:949-58. 1999..The present study tested whether short-term, abruptly initiated training can cause corpus luteum dysfunction when exercise is limited to either the follicular or luteal phase of the cycle...
- Food attitudes in female athletes: association with menstrual cycle lengthNancy I Williams
Department of Kinesiology, Noll Laboratory, The Pennsylvania State University, University Park, PA 16802, USA
J Sports Sci 24:979-86. 2006..In conclusion, irregularly short or long menstrual cycle length is associated with subtle indications of higher risk of disordered eating in female athletes...
- Lessons from experimental disruptions of the menstrual cycle in humans and monkeysNancy I Williams
Department of Kinesiology, Pennsylvania State University, University Park, PA 16802, USA
Med Sci Sports Exerc 35:1564-72. 2003..Lastly, because EAMD is often associated with disordered eating, future prospective studies in humans should incorporate the potential interaction of disordered eating and psychosocial stress on EAMD...
- The role of exercise in the prevention and treatment of osteoporosis and osteoarthritisN A Sharkey
Associate Professor, Center for Locomotion Studies and Department of Kinesiology, The Pennsylvania State University, University Park, Pennsylvania 16802 5702, USA
Nurs Clin North Am 35:209-21. 2000..In addition to its potential impact on the disease processes themselves, exercise improves general health and well being, enhances quality of life, and preserves physical independence...
- High prevalence of subtle and severe menstrual disturbances in exercising women: confirmation using daily hormone measuresM J De Souza
Women s Health and Exercise Laboratory, Department of Kinesiology, Penn State University, Noll Laboratory, University Park, PA 16802, USA
Hum Reprod 25:491-503. 2010..Secondly, the prevalence of oligomenorrhea and amenorrhea was also determined via measurement of daily urinary ovarian steroids rather than self report alone...
- Effects of physical activity on vasomotor symptoms: examination using objective and subjective measuresSteriani Elavsky
Department of Kinesiology, The Pennsylvania State University, University Park, PA 16802, USA
Menopause 19:1095-103. 2012..The empirical support for the beneficial effects of PA on vasomotor symptoms has, however, been mixed. The purpose of this study was to assess the effects of acute aerobic exercise and daily PA on menopausal vasomotor symptoms...
- Leptin and the skeletonTom Whipple
Department of Kinesiology, The Pennsylvania State University, University Park, USA
Clin Endocrinol (Oxf) 57:701-11. 2002
- Circulating ghrelin is sensitive to changes in body weight during a diet and exercise program in normal-weight young womenH J Leidy
Noll Physiological Research Center and the Department of Kinesiology, Pennsylvania State University, University Park, Pennsylvania 16802, USA
J Clin Endocrinol Metab 89:2659-64. 2004..These findings suggest that ghrelin responds in a compensatory manner to changes in energy homeostasis in healthy young women, and that ghrelin exhibits particular sensitivity to changes in body weight...
- The relationship of natural killer cell counts, perforin mRNA and CD2 expression to post-exercise natural killer cell activity in humansM P Miles
Department of Biochemistry and Molecular Biology, The Pennsylvania State University, State College, PA, USA
Acta Physiol Scand 174:317-25. 2002....
- Characterization of the diurnal rhythm of peptide YY and its association with energy balance parameters in normal-weight premenopausal womenBrenna R Hill
Women s Health and Exercise Laboratory and the Department of Kinesiology, Pennsylvania State University, University Park, PA 16802, USA
Am J Physiol Endocrinol Metab 301:E409-15. 2011..Thus, PYY varies in accordance with energy content and RMR, supporting a role for PYY in energy balance modulation...
- Severity of energy-related menstrual disturbances increases in proportion to indices of energy conservation in exercising womenMary Jane De Souza
Women s Exercise and Bone Health Laboratory, Graduate Department of Exercise Science, University of Toronto, Toronto, Ontario, Canada
Fertil Steril 88:971-5. 2007..These data provide further evidence of the tight association between energy balance and reproduction and suggest that subtle declines in energy availability can produce clinically recognized menstrual disturbances...
- Synergism between psychosocial and metabolic stressors: impact on reproductive function in cynomolgus monkeysNancy I Williams
Department of Psychiatry, University of Pittsburgh, 3811 O Hara St, Pittsburgh, PA 15213, USA
Am J Physiol Endocrinol Metab 293:E270-6. 2007..61, P = 0.008). These findings suggest that infertility due to hypothalamic hypogonadism can result from the combination of commonplace, seemingly minor stressors that often escape clinical attention...
- The effects of metformin and rosiglitazone, alone and in combination, on the ovary and endometrium in polycystic ovary syndromeRichard S Legro
Department of Obstetrics and Gynecology, The Pennsylvania State University College of Medicine, Hershey, PA, USA
Am J Obstet Gynecol 196:402.e1-10; discussion 402.e10-1. 2007..To examine the effects of metformin and rosiglitazone, alone and in combination, on endometrial histology and ovarian steroid production...
- Effects of lifetime exercise on the outcome of in vitro fertilizationAnne B Loucks
Obstet Gynecol 109:456-7. 2007
- Validity of methods for analyzing urinary steroid data to detect ovulation in athletesHeather J McConnell
Noll Physiological Research Center, Pennsylvania State University, University Park, PA, USA
Med Sci Sports Exerc 34:1836-44. 2002....
- Drive for thinness score is a proxy indicator of energy deficiency in exercising womenMary Jane De Souza
Women s Exercise and Bone Health Laboratory, Faculty of Physical Education and Health, University of Toronto, Toronto, Ont, Canada
Appetite 48:359-67. 2007....
- Physiological aspects and clinical sequelae of energy deficiency and hypoestrogenism in exercising womenMary Jane De Souza
Women s Exercise and Bone Health Laboratory, Faculty of Physical Education and Health, University of Toronto, Toronto, Ontario, Canada
Hum Reprod Update 10:433-48. 2004..This paper critically reviews the physiological aspects and clinical sequelae of energy deficiency and hypoestrogenism associated with the female athlete triad in exercising women...
- Fasting ghrelin levels in physically active women: relationship with menstrual disturbances and metabolic hormonesMary Jane De Souza
Women s Exercise and Bone Health Laboratory, Faculty of Physical Education and Health, University of Toronto, 55 Harbord Street, Toronto, Ontario, Canada M5S 2W6
J Clin Endocrinol Metab 89:3536-42. 2004....
- Beyond hypoestrogenism in amenorrheic athletes: energy deficiency as a contributing factor for bone lossMary Jane De Souza
Women s Exercise and Bone Health Laboratory, Faculty of Physical Education and Health, University of Toronto, 55 Harbord Street, Toronto, Ontario, M5S 2W6, Canada
Curr Sports Med Rep 4:38-44. 2005..These hormones (IGF-1 and leptin) play an important role in modulating bone turnover and bone mineral density in these women...
- Female athlete triad errors and misunderstandingsNancy I Williams
Med Sci Sports Exerc 38:1021; author reply 1022. 2006
- Neuromuscular performance and knee laxity do not change across the menstrual cycle in female athletesJay Hertel
University of Virginia, Charlottesville, VA 22904 4407, USA
Knee Surg Sports Traumatol Arthrosc 14:817-22. 2006..These results suggest that neuromuscular control and knee joint laxity do not change substantially across the menstrual cycle of females despite varying estrogen and progesterone levels...
- The presence of both an energy deficiency and estrogen deficiency exacerbate alterations of bone metabolism in exercising womenMary Jane De Souza
Women s Exercise and Bone Health Laboratory, Department of Exercise Sciences, University of Toronto, Toronto, Ontario, Canada
Bone 43:140-8. 2008..Bone loss in amenorrheic athletes has been attributed to energy deficiency-related suppression of bone formation, but not increased resorption despite hypoestrogenism...
- Walking for health in pregnancy: assessment by indirect calorimetry and accelerometryJennifer M DiNallo
Department of Kinesiology, The Pennsylvania State University, University Park, PA 16802 5701, USA
Res Q Exerc Sport 79:28-35. 2008..Encouraging pregnant women to walk for 30-40 min per day at a self-selected walking pace may be an appropriate public health recommendation...
- Exercise effect on oxidative stress is independent of change in estrogen metabolismKathryn H Schmitz
Division of Clinical Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, 423 Guardian Drive, Philadelphia, PA 19104, USA
Cancer Epidemiol Biomarkers Prev 17:220-3. 2008..The purpose of the study is to determine the effect of 15 weeks of aerobic exercise on lipid peroxidation, endogenous estrogens, and body composition in young, healthy eumenorrheic women...
- Effect of energy deficiency on estrogen metabolism in premenopausal womenKim C Westerlind
Division of Endocrinology, Metabolism and Diabetes, School of Medicine, University of Colorado at Denver and Health Sciences Center, Denver, CO 80214, USA
Med Sci Sports Exerc 39:1090-7. 2007..We sought to determine whether 4 months of moderate-intensity exercise coupled with calorie restriction would result in changes in urinary 2-OHE1, 16alpha-OHE1, or 2/16 in sedentary, premenopausal, eumenorrheic women...
- Twenty-four-hour ghrelin is elevated after calorie restriction and exercise training in non-obese womenHeather J Leidy
Noll Laboratory, Department of Kinesiology, Pennsylvania State University, University Park, PA 16802, USA
Obesity (Silver Spring) 15:446-55. 2007..The purpose of this study was to determine whether chronic energy deficiency achieved with caloric restriction combined with exercise is associated with changes in the 24-hour profile of ghrelin in non-obese, pre-menopausal women...
- BIOENERGETICS OF EXERCISE-INDUCED MENSTRUAL DISTURBANCESNancy Williams; Fiscal Year: 2003..The results will also expand our understanding of the mechanism of the modulation of reproductive function by energy availability. ..