Nancy Williams

Summary

Affiliation: Pennsylvania State University
Country: USA

Publications

  1. ncbi Acute effects of moderate intensity resistance exercise on bone cell activity
    T J Whipple
    Department of Kinesiology and Noll Laboratory, Pennsylvania State University, Hershey, PA, USA
    Int J Sports Med 25:496-501. 2004
  2. ncbi Decreased luteinizing hormone pulse frequency is associated with elevated 24-hour ghrelin after calorie restriction and exercise in premenopausal women
    Jennifer L Scheid
    Women s Health and Exercise Laboratory, Noll Laboratory, Dept of Kinesiology, Penn State University, University Park, PA 16802, USA
    Am J Physiol Endocrinol Metab 304:E109-16. 2013
  3. ncbi Estrogen and progesterone exposure is reduced in response to energy deficiency in women aged 25-40 years
    N I Williams
    Department of Kinesiology, Women s Health and Exercise Laboratories, Penn State University, Noll Laboratory, University Park, PA 16802, USA
    Hum Reprod 25:2328-39. 2010
  4. ncbi Effects of short-term strenuous endurance exercise upon corpus luteum function
    N I Williams
    Department of Health Sciences, Sargent College, Boston University, MA, USA
    Med Sci Sports Exerc 31:949-58. 1999
  5. ncbi Food attitudes in female athletes: association with menstrual cycle length
    Nancy I Williams
    Department of Kinesiology, Noll Laboratory, The Pennsylvania State University, University Park, PA 16802, USA
    J Sports Sci 24:979-86. 2006
  6. ncbi Lessons from experimental disruptions of the menstrual cycle in humans and monkeys
    Nancy I Williams
    Department of Kinesiology, Pennsylvania State University, University Park, PA 16802, USA
    Med Sci Sports Exerc 35:1564-72. 2003
  7. ncbi High prevalence of subtle and severe menstrual disturbances in exercising women: confirmation using daily hormone measures
    M J De Souza
    Women s Health and Exercise Laboratory, Department of Kinesiology, Penn State University, Noll Laboratory, University Park, PA 16802, USA
    Hum Reprod 25:491-503. 2010
  8. ncbi The role of exercise in the prevention and treatment of osteoporosis and osteoarthritis
    N A Sharkey
    Associate Professor, Center for Locomotion Studies and Department of Kinesiology, The Pennsylvania State University, University Park, Pennsylvania 16802 5702, USA
    Nurs Clin North Am 35:209-21. 2000
  9. ncbi Leptin and the skeleton
    Tom Whipple
    Department of Kinesiology, The Pennsylvania State University, University Park, USA
    Clin Endocrinol (Oxf) 57:701-11. 2002
  10. ncbi Circulating ghrelin is sensitive to changes in body weight during a diet and exercise program in normal-weight young women
    H J Leidy
    Noll Physiological Research Center and the Department of Kinesiology, Pennsylvania State University, University Park, Pennsylvania 16802, USA
    J Clin Endocrinol Metab 89:2659-64. 2004

Research Grants

  1. BIOENERGETICS OF EXERCISE-INDUCED MENSTRUAL DISTURBANCES
    Nancy Williams; Fiscal Year: 2003

Collaborators

Detail Information

Publications28

  1. ncbi Acute effects of moderate intensity resistance exercise on bone cell activity
    T J Whipple
    Department of Kinesiology and Noll Laboratory, Pennsylvania State University, Hershey, PA, USA
    Int J Sports Med 25:496-501. 2004
    ..Further work is needed to determine if long-term benefits to bone strength follow with persistent training...
  2. ncbi Decreased luteinizing hormone pulse frequency is associated with elevated 24-hour ghrelin after calorie restriction and exercise in premenopausal women
    Jennifer L Scheid
    Women s Health and Exercise Laboratory, Noll Laboratory, Dept of Kinesiology, Penn State University, University Park, PA 16802, USA
    Am J Physiol Endocrinol Metab 304:E109-16. 2013
    ..704, P = 0.001). Elevated total ghrelin concentrations are associated with the suppression of LH pulsatility in premenopausal women and may play a role in the suppression of reproductive function following weight loss...
  3. ncbi Estrogen and progesterone exposure is reduced in response to energy deficiency in women aged 25-40 years
    N I Williams
    Department of Kinesiology, Women s Health and Exercise Laboratories, Penn State University, Noll Laboratory, University Park, PA 16802, USA
    Hum Reprod 25:2328-39. 2010
    ..This study aimed to test the hypothesis that moderate exercise training combined with caloric restriction would produce significant menstrual disturbances and alterations in ovarian steroids in premenopausal women...
  4. ncbi Effects of short-term strenuous endurance exercise upon corpus luteum function
    N I Williams
    Department of Health Sciences, Sargent College, Boston University, MA, USA
    Med Sci Sports Exerc 31:949-58. 1999
    ..The present study tested whether short-term, abruptly initiated training can cause corpus luteum dysfunction when exercise is limited to either the follicular or luteal phase of the cycle...
  5. ncbi Food attitudes in female athletes: association with menstrual cycle length
    Nancy I Williams
    Department of Kinesiology, Noll Laboratory, The Pennsylvania State University, University Park, PA 16802, USA
    J Sports Sci 24:979-86. 2006
    ..In conclusion, irregularly short or long menstrual cycle length is associated with subtle indications of higher risk of disordered eating in female athletes...
  6. ncbi Lessons from experimental disruptions of the menstrual cycle in humans and monkeys
    Nancy I Williams
    Department of Kinesiology, Pennsylvania State University, University Park, PA 16802, USA
    Med Sci Sports Exerc 35:1564-72. 2003
    ..Lastly, because EAMD is often associated with disordered eating, future prospective studies in humans should incorporate the potential interaction of disordered eating and psychosocial stress on EAMD...
  7. ncbi High prevalence of subtle and severe menstrual disturbances in exercising women: confirmation using daily hormone measures
    M J De Souza
    Women s Health and Exercise Laboratory, Department of Kinesiology, Penn State University, Noll Laboratory, University Park, PA 16802, USA
    Hum Reprod 25:491-503. 2010
    ..Secondly, the prevalence of oligomenorrhea and amenorrhea was also determined via measurement of daily urinary ovarian steroids rather than self report alone...
  8. ncbi The role of exercise in the prevention and treatment of osteoporosis and osteoarthritis
    N A Sharkey
    Associate Professor, Center for Locomotion Studies and Department of Kinesiology, The Pennsylvania State University, University Park, Pennsylvania 16802 5702, USA
    Nurs Clin North Am 35:209-21. 2000
    ..In addition to its potential impact on the disease processes themselves, exercise improves general health and well being, enhances quality of life, and preserves physical independence...
  9. ncbi Leptin and the skeleton
    Tom Whipple
    Department of Kinesiology, The Pennsylvania State University, University Park, USA
    Clin Endocrinol (Oxf) 57:701-11. 2002
  10. ncbi Circulating ghrelin is sensitive to changes in body weight during a diet and exercise program in normal-weight young women
    H J Leidy
    Noll Physiological Research Center and the Department of Kinesiology, Pennsylvania State University, University Park, Pennsylvania 16802, USA
    J Clin Endocrinol Metab 89:2659-64. 2004
    ..These findings suggest that ghrelin responds in a compensatory manner to changes in energy homeostasis in healthy young women, and that ghrelin exhibits particular sensitivity to changes in body weight...
  11. ncbi The relationship of natural killer cell counts, perforin mRNA and CD2 expression to post-exercise natural killer cell activity in humans
    M P Miles
    Department of Biochemistry and Molecular Biology, The Pennsylvania State University, State College, PA, USA
    Acta Physiol Scand 174:317-25. 2002
    ....
  12. ncbi Characterization of the diurnal rhythm of peptide YY and its association with energy balance parameters in normal-weight premenopausal women
    Brenna R Hill
    Women s Health and Exercise Laboratory and the Department of Kinesiology, Pennsylvania State University, University Park, PA 16802, USA
    Am J Physiol Endocrinol Metab 301:E409-15. 2011
    ..Thus, PYY varies in accordance with energy content and RMR, supporting a role for PYY in energy balance modulation...
  13. ncbi Severity of energy-related menstrual disturbances increases in proportion to indices of energy conservation in exercising women
    Mary Jane De Souza
    Women s Exercise and Bone Health Laboratory, Graduate Department of Exercise Science, University of Toronto, Toronto, Ontario, Canada
    Fertil Steril 88:971-5. 2007
    ..These data provide further evidence of the tight association between energy balance and reproduction and suggest that subtle declines in energy availability can produce clinically recognized menstrual disturbances...
  14. ncbi Synergism between psychosocial and metabolic stressors: impact on reproductive function in cynomolgus monkeys
    Nancy I Williams
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara St, Pittsburgh, PA 15213, USA
    Am J Physiol Endocrinol Metab 293:E270-6. 2007
    ..61, P = 0.008). These findings suggest that infertility due to hypothalamic hypogonadism can result from the combination of commonplace, seemingly minor stressors that often escape clinical attention...
  15. ncbi The effects of metformin and rosiglitazone, alone and in combination, on the ovary and endometrium in polycystic ovary syndrome
    Richard S Legro
    Department of Obstetrics and Gynecology, The Pennsylvania State University College of Medicine, Hershey, PA, USA
    Am J Obstet Gynecol 196:402.e1-10; discussion 402.e10-1. 2007
    ..To examine the effects of metformin and rosiglitazone, alone and in combination, on endometrial histology and ovarian steroid production...
  16. ncbi Drive for thinness score is a proxy indicator of energy deficiency in exercising women
    Mary Jane De Souza
    Women s Exercise and Bone Health Laboratory, Faculty of Physical Education and Health, University of Toronto, Toronto, Ont, Canada
    Appetite 48:359-67. 2007
    ....
  17. ncbi Effects of lifetime exercise on the outcome of in vitro fertilization
    Anne B Loucks
    Obstet Gynecol 109:456-7. 2007
  18. ncbi Validity of methods for analyzing urinary steroid data to detect ovulation in athletes
    Heather J McConnell
    Noll Physiological Research Center, Pennsylvania State University, University Park, PA, USA
    Med Sci Sports Exerc 34:1836-44. 2002
    ....
  19. ncbi Female athlete triad errors and misunderstandings
    Nancy I Williams
    Med Sci Sports Exerc 38:1021; author reply 1022. 2006
  20. ncbi Physiological aspects and clinical sequelae of energy deficiency and hypoestrogenism in exercising women
    Mary Jane De Souza
    Women s Exercise and Bone Health Laboratory, Faculty of Physical Education and Health, University of Toronto, Toronto, Ontario, Canada
    Hum Reprod Update 10:433-48. 2004
    ..This paper critically reviews the physiological aspects and clinical sequelae of energy deficiency and hypoestrogenism associated with the female athlete triad in exercising women...
  21. ncbi Fasting ghrelin levels in physically active women: relationship with menstrual disturbances and metabolic hormones
    Mary Jane De Souza
    Women s Exercise and Bone Health Laboratory, Faculty of Physical Education and Health, University of Toronto, 55 Harbord Street, Toronto, Ontario, Canada M5S 2W6
    J Clin Endocrinol Metab 89:3536-42. 2004
    ....
  22. ncbi Beyond hypoestrogenism in amenorrheic athletes: energy deficiency as a contributing factor for bone loss
    Mary Jane De Souza
    Women's Exercise and Bone Health Laboratory, Faculty of Physical Education and Health, University of Toronto, 55 Harbord Street, Toronto, Ontario, M5S 2W6, Canada
    Curr Sports Med Rep 4:38-44. 2005
    ..These hormones (IGF-1 and leptin) play an important role in modulating bone turnover and bone mineral density in these women...
  23. ncbi The presence of both an energy deficiency and estrogen deficiency exacerbate alterations of bone metabolism in exercising women
    Mary Jane De Souza
    Women s Exercise and Bone Health Laboratory, Department of Exercise Sciences, University of Toronto, Toronto, Ontario, Canada
    Bone 43:140-8. 2008
    ..Bone loss in amenorrheic athletes has been attributed to energy deficiency-related suppression of bone formation, but not increased resorption despite hypoestrogenism...
  24. ncbi Walking for health in pregnancy: assessment by indirect calorimetry and accelerometry
    Jennifer M DiNallo
    Department of Kinesiology, The Pennsylvania State University, University Park, PA 16802 5701, USA
    Res Q Exerc Sport 79:28-35. 2008
    ..Encouraging pregnant women to walk for 30-40 min per day at a self-selected walking pace may be an appropriate public health recommendation...
  25. ncbi Exercise effect on oxidative stress is independent of change in estrogen metabolism
    Kathryn H Schmitz
    Division of Clinical Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, 423 Guardian Drive, Philadelphia, PA 19104, USA
    Cancer Epidemiol Biomarkers Prev 17:220-3. 2008
    ..The purpose of the study is to determine the effect of 15 weeks of aerobic exercise on lipid peroxidation, endogenous estrogens, and body composition in young, healthy eumenorrheic women...
  26. ncbi Effect of energy deficiency on estrogen metabolism in premenopausal women
    Kim C Westerlind
    Division of Endocrinology, Metabolism and Diabetes, School of Medicine, University of Colorado at Denver and Health Sciences Center, Denver, CO 80214, USA
    Med Sci Sports Exerc 39:1090-7. 2007
    ..We sought to determine whether 4 months of moderate-intensity exercise coupled with calorie restriction would result in changes in urinary 2-OHE1, 16alpha-OHE1, or 2/16 in sedentary, premenopausal, eumenorrheic women...
  27. ncbi Neuromuscular performance and knee laxity do not change across the menstrual cycle in female athletes
    Jay Hertel
    University of Virginia, Charlottesville, VA 22904 4407, USA
    Knee Surg Sports Traumatol Arthrosc 14:817-22. 2006
    ..These results suggest that neuromuscular control and knee joint laxity do not change substantially across the menstrual cycle of females despite varying estrogen and progesterone levels...
  28. ncbi Twenty-four-hour ghrelin is elevated after calorie restriction and exercise training in non-obese women
    Heather J Leidy
    Noll Laboratory, Department of Kinesiology, Pennsylvania State University, University Park, PA 16802, USA
    Obesity (Silver Spring) 15:446-55. 2007
    ..The purpose of this study was to determine whether chronic energy deficiency achieved with caloric restriction combined with exercise is associated with changes in the 24-hour profile of ghrelin in non-obese, pre-menopausal women...

Research Grants3

  1. BIOENERGETICS OF EXERCISE-INDUCED MENSTRUAL DISTURBANCES
    Nancy Williams; Fiscal Year: 2003
    ..The results will also expand our understanding of the mechanism of the modulation of reproductive function by energy availability. ..