Research Topics
Species | S G WestSummaryAffiliation: Pennsylvania State University Country: USA Publications
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Publications
Diets containing pistachios reduce systolic blood pressure and peripheral vascular responses to stress in adults with dyslipidemiaSheila G West
Department of Biobehavioral Health, Pennsylvania State University, University Park, PA 16802, USA
Hypertension 60:58-63. 2012..There was no effect of diet on fasting flow-mediated dilation. Reductions in peripheral vascular constriction and the resulting decrease in hemodynamic load may be important contributors to lower risk in nut consumers...
An increase in dietary n-3 fatty acids decreases a marker of bone resorption in humansAmy E Griel
Department of Nutritional Sciences, 126 S Henderson Bldg, The Pennsylvania State University, University Park, PA 16802, USA
Nutr J 6:2. 2007..The results indicate that plant sources of dietary n-3 PUFA may have a protective effect on bone metabolism via a decrease in bone resorption in the presence of consistent levels of bone formation...
The effect of walnut intake on factors related to prostate and vascular health in older menKim J Spaccarotella
Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802, USA
Nutr J 7:13. 2008..Tocopherols may protect against prostate cancer and cardiovascular disease (CVD)...
Effects of diets high in walnuts and flax oil on hemodynamic responses to stress and vascular endothelial functionSheila G West
Department of Biobehavioral Health, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
J Am Coll Nutr 29:595-603. 2010..In a previous article, we showed significant reductions in low-density lipoprotein cholesterol and several markers of inflammation with increasing intake of alpha-linolenic acid (ALA) from walnuts and flax...
Effect of diet on vascular reactivity: an emerging marker for vascular riskS G West
Department of Biobehavioral Health, Pennsylvania State University, 315 Health and Human Development Building East, University Park, PA 16802, USA
Curr Atheroscler Rep 3:446-55. 2001....
Biological correlates of day-to-day variation in flow-mediated dilation in individuals with Type 2 diabetes: a study of test-retest reliabilityS G West
Department of Biobehavioral Health, The Pennsylvania State University, 315 Health and Human Development Building East, University Park, PA 16802, USA
Diabetologia 47:1625-31. 2004..In this study, we tested the hypothesis that larger day-to-day changes in insulin and glucose are associated with larger fluctuations in FMD...
Oral L-arginine improves hemodynamic responses to stress and reduces plasma homocysteine in hypercholesterolemic menSheila G West
Department of Biobehavioral Health at Pennsylvania State University, University Park, PA 16802, USA
J Nutr 135:212-7. 2005..This study is the first to describe a hemodynamic mechanism for the hypotensive effect of oral L-arginine and the first to show substantial reductions in homocysteine with oral administration...
Effects of including soy protein in a blood cholesterol-lowering diet on markers of cardiac risk in men and in postmenopausal women with and without hormone replacement therapySheila G West
Department of Biobehavioral Health, Pennsylvania State University, University Park, Pennsylvania 16802, USA
J Womens Health (Larchmt) 14:253-62. 2005..However, it is not clear whether adding soy to a low-fat diet has additional lipid-lowering benefits, and few previous studies have examined these effects in women using hormone replacement therapy (HRT+)...
Acute effects of monounsaturated fatty acids with and without omega-3 fatty acids on vascular reactivity in individuals with type 2 diabetesS G West
Department of Biobehavioral Health, The Pennsylvania State University, University Park, PA, USA
Diabetologia 48:113-22. 2005..The fatty acid composition of the meal and the metabolic status of the individual determine the vascular effects of a high-fat meal...
Dietary alpha-linolenic acid reduces inflammatory and lipid cardiovascular risk factors in hypercholesterolemic men and womenGuixiang Zhao
Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA, USA
J Nutr 134:2991-7. 2004..05); the ALA Diet decreased HDL cholesterol and apolipoprotein AI compared with the AAD (P < 0.05). ALA appears to decrease CVD risk by inhibiting vascular inflammation and endothelial activation beyond its lipid-lowering effects...
Effects of pistachios on cardiovascular disease risk factors and potential mechanisms of action: a dose-response studySarah K Gebauer
Integrative Biosciences and Biobehavioral Health, Pennsylvania State University, University Park, PA 16802, USA
Am J Clin Nutr 88:651-9. 2008..Nut consumption lowers cardiovascular disease (CVD) risk. Studies are lacking about the effects of pistachios, a nutrient-dense nut, on CVD risk factors, dose-response relations, and lipid-lowering mechanisms...
Transdermal estrogen reduces vascular resistance and serum cholesterol in postmenopausal womenS G West
Department of Biobehavioral Health, The Pennsylvania State University, University Park, 16802, USA
Am J Obstet Gynecol 184:926-33. 2001..Future studies comparing novel hormone regimens with oral hormone replacement therapy should include multiple risk markers to allow better assessment of their potential impact on coronary artery health...
Lipid response to a low-fat diet with or without soy is modified by C-reactive protein status in moderately hypercholesterolemic adultsKirsten F Hilpert
Department of Nutritional Sciences, The Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA, USA
J Nutr 135:1075-9. 2005..5%) compared with the run-in diet. These results suggest that inflammation may not only attenuate lipid responses, but also aggravate dyslipidemia in hypercholesterolemic subjects consuming a cholesterol-lowering diet...
Associations between eating competence and cardiovascular disease biomarkersTricia L Psota
Department of Nutritional Sciences, The Pennsylvania State University, University Park, Pennsylvania, USA
J Nutr Educ Behav 39:S171-8. 2007..Explore the relationship between eating competence (EC) and biomarkers of risk for cardiovascular disease (CVD)...
Milk products, dietary patterns and blood pressure managementPenny M Kris-Etherton
Department of Nutritional Sciences, 110 Chandlee Laboratory, Penn State University, University Park, PA 16802, USA
J Am Coll Nutr 28:103S-19S. 2009..A growing evidence base shows that dairy product consumption is involved in the regulation of BP. Consequently, inclusion of dairy products in a heart healthy diet is an important focal point to attain BP benefits...
Effects of dairy products on intracellular calcium and blood pressure in adults with essential hypertensionKirsten F Hilpert
Department of Nutritional Sciences, The Pennsylvania State University, University Park, Pennsylvania, USA
J Am Coll Nutr 28:142-9. 2009..Consumption of dairy foods has been associated with lower blood pressure in certain populations...
Dose-response effects of omega-3 fatty acids on triglycerides, inflammation, and endothelial function in healthy persons with moderate hypertriglyceridemiaAnn C Skulas-Ray
Department of Nutritional Sciences, Pennsylvania State University, University Park, PA, USA
Am J Clin Nutr 93:243-52. 2011..Studies using higher doses have shown evidence of reduced inflammation and improved endothelial function. Few studies have compared these doses...
Oral contraceptive use is associated with increased cardiovascular reactivity in nonsmokersS G West
Pennsylvania State University, USA
Ann Behav Med 23:149-57. 2001..However OC use among nonsmoking women is associated with greater cardiovascular reactivity to stress...
Pistachios increase serum antioxidants and lower serum oxidized-LDL in hypercholesterolemic adultsColin D Kay
Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802, USA
J Nutr 140:1093-8. 2010....
Dietary alpha-linolenic acid inhibits proinflammatory cytokine production by peripheral blood mononuclear cells in hypercholesterolemic subjectsGuixiang Zhao
Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA, USA
Am J Clin Nutr 85:385-91. 2007..Atherosclerosis is a chronic inflammatory disease. We previously reported that a diet high in alpha-linolenic acid (ALA) reduces lipid and inflammatory cardiovascular disease risk factors in hypercholesterolemic subjects...
Postprandial effect of n-3 polyunsaturated fatty acids on apolipoprotein B-containing lipoproteins and vascular reactivity in type 2 diabetesKirsten F Hilpert
Department of Nutritional Sciences and The Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA, USA
Am J Clin Nutr 85:369-76. 2007..Plasma lipoproteins may be classified by their apolipoprotein composition. The lipoprotein subclass containing apolipoproteins B and C (LpB:C) is considered the most atherogenic...
Effect of cow milk on food folate bioavailability in young womenMary Frances Picciano
Department of Nutrition, Pennsylvania State University, University Park, USA
Am J Clin Nutr 80:1565-9. 2004..The findings of animal and human studies suggest that a certain component in milk enhances food folate bioavailability...
Genetic and environmental influences on blood pressure and pulse pressure among adult African AmericansDwayne T Brandon
Department of Biobehavioral Health, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
Ethn Dis 13:193-9. 2003....
Anti-inflammatory effects of polyunsaturated fatty acids in THP-1 cellsGuixiang Zhao
Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA, USA
Biochem Biophys Res Commun 336:909-17. 2005..The results indicate that the anti-inflammatory effects of polyunsaturated fatty acids may be, in part, due to the inhibition of NF-kappaB activation via activation of PPARgamma...
Omega-3 fatty acid concentrates in the treatment of moderate hypertriglyceridemiaAnn C Skulas-Ray
Pennsylvania State University, Department of Nutritional Sciences, University Park, PA, USA
Expert Opin Pharmacother 9:1237-48. 2008..Prescription omega-3 fatty acid concentrates (P-OM3) are indicated for use in people with very high triglycerides (> 500 mg/dl). Current guidelines recommend that triglycerides should be less < 150 mg/dl...
Dietary sodium restriction alters postprandial ghrelin: implications for race differences in obesityKimberly A Brownley
Department of Psychiatry, University of North Carolina at Chapel Hill 27599 7175, USA
Ethn Dis 16:844-51. 2006..To examine the effect of sodium restriction on the appetite-stimulating hormone, ghrelin, as a function of race, salt sensitivity, and obesity...
Oxytocinergic activity is linked to lower blood pressure and vascular resistance during stress in postmenopausal women on estrogen replacementKathleen C Light
School of Medicine, University of North Carolina at Chapel Hill, NC 27599 7175, USA
Horm Behav 47:540-8. 2005..The findings suggest that enhanced oxytocinergic activity may contribute to BP decreases associated with ERT in more responsive postmenopausal women...
Cardiovascular effects of 6 months of hormone replacement therapy versus placebo: differences associated with years since menopauseKimberly A Brownley
Department of Psychiatry, University of North Carolina, Chapel Hill, 27599 7175, USA
Am J Obstet Gynecol 190:1052-8. 2004....
Soy protein with or without isoflavones: in search of a cardioprotective mechanism of actionPenny M Kris-Etherton
Am J Clin Nutr 81:5-6. 2005
Postprandial ghrelin is elevated in black compared with white womenKimberly A Brownley
Department of Psychiatry, CB 7175, University of North Carolina, Chapel Hill, North Carolina 27599 7175, USA
J Clin Endocrinol Metab 89:4457-63. 2004..These findings suggest subnormal postprandial ghrelin suppression (or faster ghrelin rebound) in black women, especially the obese, that might play a role in their increased prevalence of obesity and cardiovascular disorders...
Sympathoadrenergic mechanisms in reduced hemodynamic stress responses after exerciseKimberly A Brownley
Department of Psychiatry, University of North Carolina, Chapel Hill 27599, USA
Med Sci Sports Exerc 35:978-86. 2003..This study examines the acute effects of moderate aerobic exercise on 1) hemodynamic and sympathetic activity during behavioral stress and 2) beta-adrenergic receptor responsivity in a biracial sample of 24 sedentary adults...
Cardiovascular stress responses among Asian Indian and European American women and menCatherine M Stoney
Department of Psychology, The Ohio State University, Columbus 43210 1222, USA
Ann Behav Med 24:113-21. 2002..These data are in contrast to our expectation of decreased tendency of Asian Indians to vasodilate during psychological stress but do suggest that sex and Asian Indian ethnicity interact to influence vascular reactivity to stressors...
Acute psychological stress reduces plasma triglyceride clearanceCatherine M Stoney
Department of Psychology, Ohio State University, Columbus 43210 1222, USA
Psychophysiology 39:80-5. 2002..The diminished ability to clear an intravenous fat emulsion during stress suggests one mechanism for stress-induced elevations in lipids...
A high-fat meal increases cardiovascular reactivity to psychological stress in healthy young adultsFabijana Jakulj
University of Calgary, Department of Psychology, Calgary, AB, Canada T2N 1N4
J Nutr 137:935-9. 2007....
