David J Vandenbergh

Summary

Affiliation: Pennsylvania State University
Country: USA

Publications

  1. ncbi Finding genomic function for genetic associations in nicotine addiction research: The ENCODE project's role in future pharmacogenomic analysis
    David J Vandenbergh
    Department of Biobehavioral Health, The Pennsylvania State University, 219 Biobehavioral Health Building, University Park, PA 16802, USA Penn State Institute of the Neurosciences, 101 Life Sciences Building, University Park, PA 16802, USA Electronic address
    Pharmacol Biochem Behav 123:34-44. 2014
  2. doi Age-specific locomotor response to nicotine in yellow and mottled yellow A(vy)/a mice
    Marc A Dingman
    Department of Biobehavioral Health, The Pennsylvania State University, 219 Biobehavioral Health Building, 16802 University Park, PA, USA
    BMC Res Notes 6:497. 2013
  3. pmc Resolving candidate genes of mouse skeletal muscle QTL via RNA-Seq and expression network analyses
    Arimantas Lionikas
    School of Medical Sciences, University of Aberdeen, Aberdeen, AB25 2ZD, UK
    BMC Genomics 13:592. 2012
  4. ncbi A simple tandem repeat polymorphism is present in the eighth intron of FLJ12960, a possible queuine salvage enzyme gene
    David J Vandenbergh
    Department of Biobehavioral Health, The Pennsylvania State University, 225 Research Building E, 101 Amy Gardener House, University Park, PA 16802, USA
    Mol Cell Probes 17:319-20. 2003
  5. ncbi Optimizing DNA yield from buccal swabs in the elderly: attempts to promote buccal cell growth in culture
    David J Vandenbergh
    Center for Developmental and Health Genetics, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Am J Hum Biol 15:637-42. 2003
  6. pmc Simple tests to detect errors in high-throughput genotype data in the molecular laboratory
    David J Vandenbergh
    Center for Developmental and Health Genetics, Department of Biobehavioral Health, and Life Sciences Consortium, The Pennsylvania State University, University Park, PA 16802, USA
    J Biomol Tech 14:9-16. 2003
  7. ncbi Smoking status and the human dopamine transporter variable number of tandem repeats (VNTR) polymorphism: failure to replicate and finding that never-smokers may be different
    David J Vandenbergh
    Department of Biobehavioral Health, Center for Developmental and Health Genetics, The Pennsylvania State University, 225 Research Building E, University Park, PA 16802 2321, USA
    Nicotine Tob Res 4:333-40. 2002
  8. ncbi Dopamine receptor genes (DRD2, DRD3 and DRD4) and gene-gene interactions associated with smoking-related behaviors
    David J Vandenbergh
    Department of Biobehavioral Health, The Pennsylvania State University, University Park, PA 16802 2321, USA
    Addict Biol 12:106-16. 2007
  9. pmc Bone, muscle, and physical activity: structural equation modeling of relationships and genetic influence with age
    Dean H Lang
    Department of Kinesiology, College of Health and Human Development, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    J Bone Miner Res 24:1608-17. 2009
  10. ncbi Quantitative trait loci (QTL) analysis of longevity in C57BL/6J by DBA/2J (BXD) recombinant inbred mice
    Dean H Lang
    The Biomechanics Laboratory, Department of Kinesiology, College of Health and Human Development, The Pennsylvania State University, University Park, PA, USA
    Aging Clin Exp Res 22:8-19. 2010

Collaborators

Detail Information

Publications33

  1. ncbi Finding genomic function for genetic associations in nicotine addiction research: The ENCODE project's role in future pharmacogenomic analysis
    David J Vandenbergh
    Department of Biobehavioral Health, The Pennsylvania State University, 219 Biobehavioral Health Building, University Park, PA 16802, USA Penn State Institute of the Neurosciences, 101 Life Sciences Building, University Park, PA 16802, USA Electronic address
    Pharmacol Biochem Behav 123:34-44. 2014
    ..By serving as a bridge between genetic associations and biochemical function, ENCODE has the power to propel progress in untangling the genetic aspects of nicotine addiction - a major public health concern. ..
  2. doi Age-specific locomotor response to nicotine in yellow and mottled yellow A(vy)/a mice
    Marc A Dingman
    Department of Biobehavioral Health, The Pennsylvania State University, 219 Biobehavioral Health Building, 16802 University Park, PA, USA
    BMC Res Notes 6:497. 2013
    ..5 mg/kg) followed by open-field testing on serum corticosterone levels in a separate group of 25 young adult male Avy/a and a/a mice...
  3. pmc Resolving candidate genes of mouse skeletal muscle QTL via RNA-Seq and expression network analyses
    Arimantas Lionikas
    School of Medical Sciences, University of Aberdeen, Aberdeen, AB25 2ZD, UK
    BMC Genomics 13:592. 2012
    ..To facilitate nomination of the candidate genes responsible for these differences we examined the transcriptome of the tibialis anterior (TA) muscle of each strain by RNA-Seq...
  4. ncbi A simple tandem repeat polymorphism is present in the eighth intron of FLJ12960, a possible queuine salvage enzyme gene
    David J Vandenbergh
    Department of Biobehavioral Health, The Pennsylvania State University, 225 Research Building E, 101 Amy Gardener House, University Park, PA 16802, USA
    Mol Cell Probes 17:319-20. 2003
    ..A Simple Tandem Repeat (STR) polymorphism was identified in intron 8 of the FLJ12960 gene. Primers designed to amplify the CA repeat detect 16 alleles from 121 to 151 base pairs, with a heterozygosity of 0.74...
  5. ncbi Optimizing DNA yield from buccal swabs in the elderly: attempts to promote buccal cell growth in culture
    David J Vandenbergh
    Center for Developmental and Health Genetics, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Am J Hum Biol 15:637-42. 2003
    ..Thus, an inexpensive and efficient method exists for genetic studies of population-based samples...
  6. pmc Simple tests to detect errors in high-throughput genotype data in the molecular laboratory
    David J Vandenbergh
    Center for Developmental and Health Genetics, Department of Biobehavioral Health, and Life Sciences Consortium, The Pennsylvania State University, University Park, PA 16802, USA
    J Biomol Tech 14:9-16. 2003
    ..A set of 96 dinucleotide repeat markers that are polymorphic between the C57BL/6J and DBA/2J mouse strains and can be multiplexed is reported for use in other genotyping projects...
  7. ncbi Smoking status and the human dopamine transporter variable number of tandem repeats (VNTR) polymorphism: failure to replicate and finding that never-smokers may be different
    David J Vandenbergh
    Department of Biobehavioral Health, Center for Developmental and Health Genetics, The Pennsylvania State University, 225 Research Building E, University Park, PA 16802 2321, USA
    Nicotine Tob Res 4:333-40. 2002
    ..We have also developed an improved set of polymerase chain reaction conditions to increase the frequency of successful amplification of DAT'sw VNTR, which is a long, G+C-rich repeat...
  8. ncbi Dopamine receptor genes (DRD2, DRD3 and DRD4) and gene-gene interactions associated with smoking-related behaviors
    David J Vandenbergh
    Department of Biobehavioral Health, The Pennsylvania State University, University Park, PA 16802 2321, USA
    Addict Biol 12:106-16. 2007
    ..020) and trouble sleeping (P = 0.015). An interaction between DRD2 and DRD3 was found for trouble concentrating (P = 0.020). These relationships present possible dopamine-related responses to nicotine that warrant further study...
  9. pmc Bone, muscle, and physical activity: structural equation modeling of relationships and genetic influence with age
    Dean H Lang
    Department of Kinesiology, College of Health and Human Development, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    J Bone Miner Res 24:1608-17. 2009
    ..Further exploration of these and other mechanisms through which genes function will aid in development of individualized interventions able to exploit the numerous complex pathways contributing to skeletal health...
  10. ncbi Quantitative trait loci (QTL) analysis of longevity in C57BL/6J by DBA/2J (BXD) recombinant inbred mice
    Dean H Lang
    The Biomechanics Laboratory, Department of Kinesiology, College of Health and Human Development, The Pennsylvania State University, University Park, PA, USA
    Aging Clin Exp Res 22:8-19. 2010
    ..The aim of this study was to identify quantitative trait loci (QTLs) that influence longevity in male and female mice from twenty-three C57BL/6J by DBA/2J (BXD) recombinant inbred (RI) strains...
  11. pmc Adjusting data to body size: a comparison of methods as applied to quantitative trait loci analysis of musculoskeletal phenotypes
    Dean H Lang
    Department of Kinesiology, College of Health and Human Development, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    J Bone Miner Res 20:748-57. 2005
    ..It was found that dividing skeletal phenotypes by body mass index induced erroneous QTL results. The preferred method of body size adjustment was multiple regression...
  12. ncbi QTL analysis of trabecular bone in BXD F2 and RI mice
    Abbey L Bower
    The Biomechanics Laboratory, The Pennsylvania State University, University Park, Pennsylvania 16802 5702, USA
    J Bone Miner Res 21:1267-75. 2006
    ..QTLs for bone in the proximal tibial metaphysis were identified on several chromosomes indicating regions containing genes that regulate properties of trabecular bone...
  13. ncbi Serum alkaline phosphatase activity is regulated by a chromosomal region containing the alkaline phosphatase 2 gene (Akp2) in C57BL/6J and DBA/2J mice
    Jennifer E Foreman
    Center for Developmental and Health Genetics, The Pennsylvania State University, University Park, Pennsylvania 16802 2317, USA
    Physiol Genomics 23:295-303. 2005
    ....
  14. ncbi Genetic determinants of weight of fast- and slow-twitch skeletal muscles in old mice
    Arimantas Lionikas
    Center for Developmental and Health Genetics, The Pennsylvania State University, 101 Amy Gardner House, University Park, PA 16802, USA
    Mamm Genome 17:615-28. 2006
    ..05 for TA muscle in males (between 200 and 800 days) and females (between 500 and 800 days), respectively. Analysis of all age groups supported previous findings that the genetic effects may be muscle-, age-, and sex-specific...
  15. pmc Blood pressure and heart rate QTL in mice of the B6/D2 lineage: sex differences and environmental influences
    David A Blizard
    Center for Developmental and Health Genetics, The Pennsylvania State University, University Park, PA 16802, USA
    Physiol Genomics 36:158-66. 2009
    ..Evidence for a role for mitochondrial DNA was found for both HR and SBP. QTL for HR and SBP may differ in males and females and may be sensitive to different environmental contexts...
  16. ncbi QTL influencing baseline hematocrit in the C57BL/6J and DBA/2J lineage: age-related effects
    Frank Johannes
    Department of Biobehavioral Health, Center for Developmental and Health Genetics, The Pennsylvania State University, 101 Amy Gardner House, University Park, PA 16803, USA
    Mamm Genome 17:689-99. 2006
    ..Baseline serum hematocrit is influenced by several QTL that appear to vary with the age and sex of the animal. These QTL primarily overlap with QTL that have been shown to regulate hematopoietic stem cell phenotypes...
  17. doi Learning in the 2-bottle alcohol preference test
    David A Blizard
    Center for Developmental and Health Genetics, Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Alcohol Clin Exp Res 32:2041-6. 2008
    ..The 2-bottle preference test is a popular protocol for characterizing a rodent's selection of a variety of solutions. Little attention has been paid, however, to the role of learning in this procedure...
  18. doi Activity-related behaviors in the hole-board predict nicotine consumption in C57B6 mice perinatally exposed to nicotine
    Joseph Gyekis
    Center for Developmental and Health Genetics, The Pennsylvania State University, University Park, PA 16802, USA
    Behav Brain Res 206:139-42. 2010
    ..These results show that hole-board behaviors predict subsequent nicotine intake in mice exposed to nicotine perinatally, especially after habituation to the apparatus...
  19. doi Perinatal nicotine exposure delays genital development in mice
    Joseph Gyekis
    Center for Developmental and Health Genetics, The Pennsylvania State University, University Park, PA 16802, USA
    Reprod Toxicol 29:378-80. 2010
    ..Nicotine's perinatal effects on genital development in mice, which is interpreted as a measure of endocrine disrupting activity, were evaluated in this report...
  20. pmc Quantitative trait loci analysis of structural and material skeletal phenotypes in C57BL/6J and DBA/2 second-generation and recombinant inbred mice
    Dean H Lang
    The Center for Locomotion Studies, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    J Bone Miner Res 20:88-99. 2005
    ..QTLs for skeletal traits co-located with each other and with correlated traits such as body weight and length, adipose mass, and serum alkaline phosphatase...
  21. ncbi Sex differences in voluntary oral nicotine consumption by adolescent mice: a dose-response experiment
    Laura Cousino Klein
    Department of Biobehavioral Health, Center for Developmental and Health Genetics, 315 East Health and Human Development Building, The Pennsylvania State University, University Park, PA 16802, USA
    Pharmacol Biochem Behav 78:13-25. 2004
    ..Sex differences in nicotine consumption, but not in cotinine levels, suggest sex differences in pharmacokinetic processes that may contribute to oral nicotine consumption behavior during periadolescence...
  22. ncbi An examination of early smoking experiences and smoking status in a national cross-sectional sample
    RICHARD J O'CONNOR
    Department of Biobehavioral Health, The Pennsylvania State University, University Park, PA 16801, USA
    Addiction 100:1352-7. 2005
    ..To extend previous work showing lightheadedness from and liking for smoking to be associated with continued smoking while controlling for demographics and social influences that can also contribute to progression to established smoking...
  23. doi Gustatory, trigeminal, and olfactory aspects of nicotine intake in three mouse strains
    Joseph P Gyekis
    Department of Biobehavioral Health, Pennsylvania State University, 201 Research Building D, University Park, PA 16802, USA
    Behav Genet 42:820-9. 2012
    ....
  24. ncbi Effects of periadolescent ethanol exposure on alcohol preference in two BALB substrains
    David A Blizard
    Center for Developmental and Health Genetics, The Pennsylvania State University, University Park, PA 16802, USA
    Alcohol 34:177-85. 2004
    ....
  25. ncbi Anogenital distance measured at weaning is correlated with measures of blood chemistry and behaviors in 450-day-old female mice
    Tara K Kerin
    Center for Developmental and Health Genetics, Pennsylvania State University, 101 Amy Gardner House, University Park, PA 16802, USA
    Physiol Behav 78:697-702. 2003
    ..These findings suggest that in utero proximity to males, as indexed by AGDWTRES, may have effects on fundamental aspects of blood chemistry and behavior that extend well into mouse middle age, and could play an important role in health...
  26. pmc Communal nesting increases pup growth but has limited effects on adult behavior and neurophysiology in inbred mice
    Kathleen M Heiderstadt
    Animal Resource Program, The Pennsylvania State University, University Park, Pennsylvania, USA
    J Am Assoc Lab Anim Sci 53:152-60. 2014
    ..Communal rearing can enhance juvenile growth rates but does not change adult behavior in inbred mouse strains, although potential effects on adult neurophysiology are possible. ..
  27. ncbi Using a telephone survey to acquire genetic and behavioral data related to cigarette smoking in "made-anonymous" and "registry" samples
    Lynn T Kozlowski
    Department of Biobehavioral Health, College of Health and Human Development, The Pennsylvania State University, University Park, PA 16802, USA
    Am J Epidemiol 156:68-77. 2002
    ..The authors conclude that random digit dialing surveys coupled with mail collection of DNA may constitute a practical method of obtaining DNA samples for biobehavioral research...
  28. ncbi Laternal nicotine exposure increases nicotine preference in periadolescent male but not female C57B1/6J mice
    Laura Cousino Klein
    Department of Biobehavioral Health, Center for Developmental and Health Genetics, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Nicotine Tob Res 5:117-24. 2003
    ..Differential outcomes for males and females suggest that different processes underlie sex differences in nicotine consumption following maternal nicotine exposure...
  29. ncbi Effect of the monoamine oxidase inhibition on rewarding effects of nicotine in rodents
    Christine H Kapelewski
    Department of Biobehavioral Health, The Pennsylvania State University, University Park, PA 16802, USA
    Curr Drug Abuse Rev 4:110-21. 2011
    ..These data will enhance our understanding of the neuropharmacological effects of smoking and the value of implementing MAO inhibitors as pharmacotherapies for smoking cessation...
  30. ncbi Dopaminergic polymorphisms in Tourette syndrome: association with the DAT gene (SLC6A3)
    Dustin Y Yoon
    Department of Neurology, Johns Hopkins University School of Medicine, Harriet Lane Children s Health Building, Wolfe Street, Baltimore, Maryland 21205, USA
    Am J Med Genet B Neuropsychiatr Genet 144:605-10. 2007
    ..Since abnormalities of the dopamine transporter have been hypothesized in the pathophysiology of TS, it is possible that this could be a functional allele associated with clinical expression...
  31. ncbi DAT's not all, but it may be more than we realize
    David J Vandenbergh
    Nicotine Tob Res 4:251-2. 2002
  32. pmc Genetic effects on children's conversational language use
    Laura S DeThorne
    University of Illinois at Urbana Champaign, 901 South Sixth Street, Champaign, IL 61820, USA
    J Speech Lang Hear Res 51:423-35. 2008
    ..The present study examined the extent of genetic and environmental influences on individual differences in children's conversational language use...
  33. ncbi Norepinephrine transporter polymorphisms in Tourette syndrome with and without attention deficit hyperactivity disorder: no evidence for significant association
    Christopher A Rippel
    Department of Neurology, Johns Hopkins University School of Medicine, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA
    Psychiatr Genet 16:179-80. 2006
    ..Further research with additional NET polymorphisms and larger sample sizes are indicated in the pursuit of biomarkers for therapeutic responders...