Thomas C Stover

Summary

Affiliation: Pennsylvania State University
Country: USA

Publications

  1. ncbi request reprint Thermoresponsive and biodegradable linear-dendritic nanoparticles for targeted and sustained release of a pro-apoptotic drug
    Thomas C Stover
    Department of Pharmacology, 500 University Drive, Milton S Hershey Medical Center, Pennsylvania State University, Hershey, PA 17033, USA
    Biomaterials 29:359-69. 2008
  2. ncbi request reprint Ceramide recruits and activates protein kinase C zeta (PKC zeta) within structured membrane microdomains
    Todd E Fox
    Department of Pharmacology College of Medicine, Pennsylvania State University, Hershey, Pennsylvania 17033, USA
    J Biol Chem 282:12450-7. 2007
  3. ncbi request reprint Systemic delivery of liposomal short-chain ceramide limits solid tumor growth in murine models of breast adenocarcinoma
    Thomas C Stover
    Department of Pharmacology, Pennsylvania State College of Medicine, Hershey, Pennsylvania 17033, USA
    Clin Cancer Res 11:3465-74. 2005

Collaborators

  • Mark Kester
  • Jong K Yun
  • Todd E Fox
  • Murali Nagarajan
  • Stanley J Naides
  • Sean M O'Neill
  • Onur Unal
  • Kristy L Houck
  • Pawel T Pomianowski

Detail Information

Publications3

  1. ncbi request reprint Thermoresponsive and biodegradable linear-dendritic nanoparticles for targeted and sustained release of a pro-apoptotic drug
    Thomas C Stover
    Department of Pharmacology, 500 University Drive, Milton S Hershey Medical Center, Pennsylvania State University, Hershey, PA 17033, USA
    Biomaterials 29:359-69. 2008
    ..The designed thermoresponsive and biodegradable linear-dendritic nanoparticles have great potential for thermally targeted and sustained release of C(6) for the treatment of solid tumors with hyperthermia...
  2. ncbi request reprint Ceramide recruits and activates protein kinase C zeta (PKC zeta) within structured membrane microdomains
    Todd E Fox
    Department of Pharmacology College of Medicine, Pennsylvania State University, Hershey, Pennsylvania 17033, USA
    J Biol Chem 282:12450-7. 2007
    ..Taken together, these data demonstrate that structured membrane microdomains are necessary for ceramide-induced activation of PKC zeta and resultant diminished Akt activity, leading to vascular smooth muscle cell growth arrest...
  3. ncbi request reprint Systemic delivery of liposomal short-chain ceramide limits solid tumor growth in murine models of breast adenocarcinoma
    Thomas C Stover
    Department of Pharmacology, Pennsylvania State College of Medicine, Hershey, Pennsylvania 17033, USA
    Clin Cancer Res 11:3465-74. 2005
    ..Together, these results indicate that bioactive ceramide analogues can be incorporated into pegylated liposomal vehicles for improved solubility, drug delivery, and antineoplastic efficacy...