Jennifer L Steiner

Summary

Affiliation: Pennsylvania State University
Country: USA

Publications

  1. doi request reprint Alcohol, Adipose Tissue and Lipid Dysregulation.
    Jennifer L Steiner
    Department of Cellular and Molecular Physiology, Penn State College of Medicine, Hershey, PA 17033, USA
    Biomolecules 7:. 2017
  2. doi request reprint Etiology of alcoholic cardiomyopathy: Mitochondria, oxidative stress and apoptosis
    Jennifer L Steiner
    Department of Cellular and Molecular Physiology, Penn State College of Medicine, 500 University Drive, Hershey, PA 17033, United States Electronic address
    Int J Biochem Cell Biol 89:125-135. 2017
  3. pmc Impact of Alcohol on Glycemic Control and Insulin Action
    Jennifer L Steiner
    Department of Cellular and Molecular Physiology, Penn State College of Medicine, Hershey, PA 17033, USA
    Biomolecules 5:2223-46. 2015
  4. pmc Moderate alcohol consumption does not impair overload-induced muscle hypertrophy and protein synthesis
    Jennifer L Steiner
    Department of Cellular and Molecular Physiology, Penn State College of Medicine, Hershey, Pennsylvania
    Physiol Rep 3:. 2015
  5. pmc Alcohol impairs skeletal muscle protein synthesis and mTOR signaling in a time-dependent manner following electrically stimulated muscle contraction
    Jennifer L Steiner
    Department of Cellular and Molecular Physiology, Pennsylvania State College of Medicine, Hershey, Pennsylvania
    J Appl Physiol (1985) 117:1170-9. 2014
  6. pmc Decreased Whole-Body Fat Mass Produced by Chronic Alcohol Consumption is Associated with Activation of S6K1-Mediated Protein Synthesis and Increased Autophagy in Epididymal White Adipose Tissue
    Kristen T Crowell
    Department of Cellular and Molecular Physiology, Penn State College Medicine, Hershey, Pennsylvania
    Alcohol Clin Exp Res 40:1832-45. 2016
  7. pmc Acute Alcohol-Induced Decrease in Muscle Protein Synthesis in Female Mice Is REDD-1 and mTOR-Independent
    Jennifer L Steiner
    Department of Cellular and Molecular Physiology, Penn State College of Medicine, 500 University Drive, Hershey, PA 17033, USA
    Alcohol Alcohol 51:242-50. 2016
  8. pmc Reduced REDD1 expression contributes to activation of mTORC1 following electrically induced muscle contraction
    Bradley S Gordon
    Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania
    Am J Physiol Endocrinol Metab 307:E703-11. 2014
  9. doi request reprint Alcoholic Cardiomyopathy: Disrupted Protein Balance and Impaired Cardiomyocyte Contractility
    Jennifer L Steiner
    Department of Cellular and Molecular Physiology, Penn State College of Medicine, Hershey, Pennsylvania
    Alcohol Clin Exp Res 41:1392-1401. 2017
  10. pmc Modulation of voltage-gated Ca2+ channels by G protein-coupled receptors in celiac-mesenteric ganglion neurons of septic rats
    Mohamed Farrag
    Department of Anesthesiology, Penn State College of Medicine, Hershey, PA, United States of America
    PLoS ONE 10:e0125566. 2015

Collaborators

  • Bradley S Gordon
  • Kristen T Crowell
  • Charles H Lang
  • Mohamed Farrag
  • Catherine S Coleman
  • Gregory E Weller
  • Victor Ruiz-Velasco
  • Lacee J Laufenberg

Detail Information

Publications15

  1. doi request reprint Alcohol, Adipose Tissue and Lipid Dysregulation.
    Jennifer L Steiner
    Department of Cellular and Molecular Physiology, Penn State College of Medicine, Hershey, PA 17033, USA
    Biomolecules 7:. 2017
    ....
  2. doi request reprint Etiology of alcoholic cardiomyopathy: Mitochondria, oxidative stress and apoptosis
    Jennifer L Steiner
    Department of Cellular and Molecular Physiology, Penn State College of Medicine, 500 University Drive, Hershey, PA 17033, United States Electronic address
    Int J Biochem Cell Biol 89:125-135. 2017
    ....
  3. pmc Impact of Alcohol on Glycemic Control and Insulin Action
    Jennifer L Steiner
    Department of Cellular and Molecular Physiology, Penn State College of Medicine, Hershey, PA 17033, USA
    Biomolecules 5:2223-46. 2015
    ....
  4. pmc Moderate alcohol consumption does not impair overload-induced muscle hypertrophy and protein synthesis
    Jennifer L Steiner
    Department of Cellular and Molecular Physiology, Penn State College of Medicine, Hershey, Pennsylvania
    Physiol Rep 3:. 2015
    ..These data show that moderate alcohol consumption does not impair muscle growth, and therefore imply that resistance exercise may be an effective therapeutic modality for alcoholic-related muscle disease. ..
  5. pmc Alcohol impairs skeletal muscle protein synthesis and mTOR signaling in a time-dependent manner following electrically stimulated muscle contraction
    Jennifer L Steiner
    Department of Cellular and Molecular Physiology, Pennsylvania State College of Medicine, Hershey, Pennsylvania
    J Appl Physiol (1985) 117:1170-9. 2014
    ..Our data indicate that acute EtOH intoxication suppresses muscle protein synthesis for at least 12 h and greatly impairs contraction-induced changes in synthesis and mTOR signaling...
  6. pmc Decreased Whole-Body Fat Mass Produced by Chronic Alcohol Consumption is Associated with Activation of S6K1-Mediated Protein Synthesis and Increased Autophagy in Epididymal White Adipose Tissue
    Kristen T Crowell
    Department of Cellular and Molecular Physiology, Penn State College Medicine, Hershey, Pennsylvania
    Alcohol Clin Exp Res 40:1832-45. 2016
    ..This study tested the hypothesis that the reduction in WAT mass in chronic alcohol-fed mice is associated with a decreased protein synthesis specifically related to impaired function of mammalian target of rapamycin (mTOR)...
  7. pmc Acute Alcohol-Induced Decrease in Muscle Protein Synthesis in Female Mice Is REDD-1 and mTOR-Independent
    Jennifer L Steiner
    Department of Cellular and Molecular Physiology, Penn State College of Medicine, 500 University Drive, Hershey, PA 17033, USA
    Alcohol Alcohol 51:242-50. 2016
    ..To determine the causative role of the REDD (regulated in development and DNA damage)-1 protein, a known negative regulator of mTOR kinase, in changes in muscle protein synthesis induced by acute alcohol administration...
  8. pmc Reduced REDD1 expression contributes to activation of mTORC1 following electrically induced muscle contraction
    Bradley S Gordon
    Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania
    Am J Physiol Endocrinol Metab 307:E703-11. 2014
    ..Overall, the data demonstrate that REDD1 expression contributes to the modulation of mTORC1 signaling following feeding- and contraction-induced activation of the pathway. ..
  9. doi request reprint Alcoholic Cardiomyopathy: Disrupted Protein Balance and Impaired Cardiomyocyte Contractility
    Jennifer L Steiner
    Department of Cellular and Molecular Physiology, Penn State College of Medicine, Hershey, Pennsylvania
    Alcohol Clin Exp Res 41:1392-1401. 2017
    ..Dysregulation of protein metabolism, including the rate of protein synthesis and autophagy, may contribute to contractile deficits and is a hallmark feature of ACM meriting additional sex-inclusive, methodologically consistent studies...
  10. pmc Modulation of voltage-gated Ca2+ channels by G protein-coupled receptors in celiac-mesenteric ganglion neurons of septic rats
    Mohamed Farrag
    Department of Anesthesiology, Penn State College of Medicine, Hershey, PA, United States of America
    PLoS ONE 10:e0125566. 2015
    ..Overall, our findings suggest that CSMG function is affected by sepsis via changes in cell size and α2-adrenergic receptor-mediated Ca2+ channel modulation. ..
  11. pmc Alcohol Differentially Alters Extracellular Matrix and Adhesion Molecule Expression in Skeletal Muscle and Heart
    Jennifer L Steiner
    Department of Cellular and Molecular Physiology, Penn State College of Medicine, Hershey, Pennsylvania
    Alcohol Clin Exp Res 39:1330-40. 2015
    ....
  12. pmc Dysregulation of skeletal muscle protein metabolism by alcohol
    Jennifer L Steiner
    Department of Cellular and Molecular Physiology, Pennsylvania State College of Medicine, Hershey, Pennsylvania
    Am J Physiol Endocrinol Metab 308:E699-712. 2015
    ..As the proportion of more economically developed countries ages and chronic illness becomes more prevalent, a better understanding of the etiology of biomedical consequences of alcohol use disorders is warranted...
  13. pmc Sepsis attenuates the anabolic response to skeletal muscle contraction
    Jennifer L Steiner
    Departments of Cellular and Molecular Physiology and Surgery, Penn State College of Medicine, Hershey, Pennsylvania
    Shock 43:344-51. 2015
    ..These findings demonstrate that resistance to contraction-induced anabolic signaling occurs during sepsis and is predominantly mTORC1-dependent. ..
  14. pmc Glucocorticoids attenuate the central sympathoexcitatory actions of insulin
    Jennifer L Steiner
    Department of Cellular and Molecular Physiology, Pennsylvania State College of Medicine, Hershey, Pennsylvania
    J Neurophysiol 112:2597-604. 2014
    ..Collectively, these findings suggest that dexamethasone attenuates the sympathoexcitatory actions of insulin through a disruption of ARC neuronal function downstream of Akt or mammalian target of rapamycin (mTOR) signaling. ..
  15. pmc Alcohol intoxication following muscle contraction in mice decreases muscle protein synthesis but not mTOR signal transduction
    Jennifer L Steiner
    Department of Cellular and Molecular Physiology, Penn State College of Medicine, Hershey, Pennsylvania
    Alcohol Clin Exp Res 39:1-10. 2015
    ..However, whether the anabolic response can be reversed when alcohol is consumed after the stimulus is unknown...