K S Smith
Affiliation: Pennsylvania State University
- Prokaryotic carbonic anhydrasesK S Smith
Department of Biochemistry and Molecular Biology, 204 South Frear Laboratory, The Pennsylvania State University, University Park, PA 16802, USA
FEMS Microbiol Rev 24:335-66. 2000..Investigations into prokaryotic carbonic anhydrase have already led to the identification of a new class (gamma) and future research will undoubtedly reveal novel functions for carbonic anhydrase in prokaryotes...
- Identification of cysteine and arginine residues essential for the phosphotransacetylase from Methanosarcina thermophilaM E Rasche
Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park 16802 4500, USA
J Bacteriol 179:7712-7. 1997..Five arginines were individually replaced with glutamine. Kinetic analysis of the altered enzymes identified R310 as essential for activity. Of the four nonessential for activity, R87 and R133 appear to be involved in binding CoA...
- Crystal structure of the "cab"-type beta class carbonic anhydrase from the archaeon Methanobacterium thermoautotrophicumP Strop
Biochemistry Option, California Institute of Technology, Pasadena, California 91125, USA
J Biol Chem 276:10299-305. 2001..The structure reveals a Hepes buffer molecule bound 8 A away from the active site zinc, which suggests a possible proton transfer pathway from the active site to the solvent...