A Catharine Ross

Summary

Affiliation: Pennsylvania State University
Country: USA

Publications

  1. pmc Use of laboratory studies for the design, explanation, and validation of human micronutrient intervention studies
    A Catharine Ross
    Department of Nutritional Sciences, Pennsylvania State University, University Park, PA, USA
    J Nutr 142:157S-60S. 2012
  2. pmc Vitamin A and retinoic acid in T cell-related immunity
    A Catharine Ross
    Department of Nutritional Sciences, Pennsylvania State University, University Park, PA, USA
    Am J Clin Nutr 96:1166S-72S. 2012
  3. pmc Augmentation of antibody responses by retinoic acid and costimulatory molecules
    A Catharine Ross
    Department of Nutritional Sciences, Pennsylvania State University, 110 Chandlee Laboratory, University Park, PA 16802, USA
    Semin Immunol 21:42-50. 2009
  4. pmc Cytochrome P450s in the regulation of cellular retinoic acid metabolism
    A Catharine Ross
    Department of Nutritional Sciences, Pennsylvania State University, University Park, PA 16802, USA
    Annu Rev Nutr 31:65-87. 2011
  5. pmc The components of VARA, a nutrient-metabolite combination of vitamin A and retinoic acid, act efficiently together and separately to increase retinyl esters in the lungs of neonatal rats
    A Catharine Ross
    Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16801, USA
    J Nutr 136:2803-7. 2006
  6. ncbi Vitamin A combined with retinoic acid increases retinol uptake and lung retinyl ester formation in a synergistic manner in neonatal rats
    A Catharine Ross
    Department of Nutritional Sciences, Pennsylvania State University, University Park, 16802, USA
    J Lipid Res 47:1844-51. 2006
  7. pmc Lung retinyl ester is low in young adult rats fed a vitamin A deficient diet after weaning, despite neonatal vitamin A supplementation and maintenance of normal plasma retinol
    A Catharine Ross
    Department of Nutritional Sciences, Pennsylvania State University, University Park, PA 16802, USA
    J Nutr 137:2213-8. 2007
  8. pmc The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know
    A Catharine Ross
    Department of Nutritional Sciences, Pennsylvania State University, University Park, Pennsylvania 16802, USA
    J Clin Endocrinol Metab 96:53-8. 2011
  9. pmc Multiple cytochrome P-450 genes are concomitantly regulated by vitamin A under steady-state conditions and by retinoic acid during hepatic first-pass metabolism
    A Catharine Ross
    Department of Nutritional Sciences, Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Physiol Genomics 43:57-67. 2011
  10. ncbi Retinol combined with retinoic acid increases retinol uptake and esterification in the lungs of young adult rats when delivered by the intramuscular as well as oral routes
    A Catharine Ross
    Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802, USA
    J Nutr 137:2371-6. 2007

Collaborators

Detail Information

Publications66

  1. pmc Use of laboratory studies for the design, explanation, and validation of human micronutrient intervention studies
    A Catharine Ross
    Department of Nutritional Sciences, Pennsylvania State University, University Park, PA, USA
    J Nutr 142:157S-60S. 2012
    ....
  2. pmc Vitamin A and retinoic acid in T cell-related immunity
    A Catharine Ross
    Department of Nutritional Sciences, Pennsylvania State University, University Park, PA, USA
    Am J Clin Nutr 96:1166S-72S. 2012
    ....
  3. pmc Augmentation of antibody responses by retinoic acid and costimulatory molecules
    A Catharine Ross
    Department of Nutritional Sciences, Pennsylvania State University, 110 Chandlee Laboratory, University Park, PA 16802, USA
    Semin Immunol 21:42-50. 2009
    ..Mechanisms may include regulation of cell populations, type 1/type 2 cytokines, and B cell-related transcription factors, leading to accelerated B cell maturation...
  4. pmc Cytochrome P450s in the regulation of cellular retinoic acid metabolism
    A Catharine Ross
    Department of Nutritional Sciences, Pennsylvania State University, University Park, PA 16802, USA
    Annu Rev Nutr 31:65-87. 2011
    ..Thus, pharmacological approaches to limiting the activity of CYP26 enzymes may extend the half-life of RA and could be useful clinically in the future...
  5. pmc The components of VARA, a nutrient-metabolite combination of vitamin A and retinoic acid, act efficiently together and separately to increase retinyl esters in the lungs of neonatal rats
    A Catharine Ross
    Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16801, USA
    J Nutr 136:2803-7. 2006
    ..Given the importance of bioactive retinoids in cell differentiation and lung development, assuring an adequate lung RE content postnatally could be of benefit for lung maturation...
  6. ncbi Vitamin A combined with retinoic acid increases retinol uptake and lung retinyl ester formation in a synergistic manner in neonatal rats
    A Catharine Ross
    Department of Nutritional Sciences, Pennsylvania State University, University Park, 16802, USA
    J Lipid Res 47:1844-51. 2006
    ..In conclusion, VARA, a 10:1 nutrient-metabolite combination, increased lung RE significantly compared with VA alone and could be a promising therapeutic option for enhancing the delivery of VA to the lungs...
  7. pmc Lung retinyl ester is low in young adult rats fed a vitamin A deficient diet after weaning, despite neonatal vitamin A supplementation and maintenance of normal plasma retinol
    A Catharine Ross
    Department of Nutritional Sciences, Pennsylvania State University, University Park, PA 16802, USA
    J Nutr 137:2213-8. 2007
    ..0001). We infer that the lungs depend, at least in part, on the uptake of dietary vitamin A, probably from chylomicrons, to develop RE stores in the postweaning growth period...
  8. pmc The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know
    A Catharine Ross
    Department of Nutritional Sciences, Pennsylvania State University, University Park, Pennsylvania 16802, USA
    J Clin Endocrinol Metab 96:53-8. 2011
    ..Urgent research and clinical priorities were identified, including reassessment of laboratory ranges for 25-hydroxyvitamin D, to avoid problems of both undertreatment and overtreatment...
  9. pmc Multiple cytochrome P-450 genes are concomitantly regulated by vitamin A under steady-state conditions and by retinoic acid during hepatic first-pass metabolism
    A Catharine Ross
    Department of Nutritional Sciences, Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Physiol Genomics 43:57-67. 2011
    ....
  10. ncbi Retinol combined with retinoic acid increases retinol uptake and esterification in the lungs of young adult rats when delivered by the intramuscular as well as oral routes
    A Catharine Ross
    Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802, USA
    J Nutr 137:2371-6. 2007
    ..m. route. Overall, VARA can increase retinol uptake and esterification in adult lungs when delivered intramuscularly as well as orally...
  11. ncbi Chylomicron margination, lipolysis, and vitamin a uptake in the lactating rat mammary gland: implications for milk retinoid content
    A Catharine Ross
    Department of Nutritional Sciences, Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Exp Biol Med (Maywood) 229:46-55. 2004
    ..The mechanism of CM margination and mammary gland uptake described here for VA may be similar for other lipophilic substances...
  12. ncbi Advances in retinoid research: mechanisms of cancer chemoprevention symposium introduction
    A Catharine Ross
    Department of Nutritional Sciences, The Pennsylvania State University, University Park 16802, USA
    J Nutr 133:271S-272S. 2003
  13. ncbi Regulation of hepatic retinol metabolism: perspectives from studies on vitamin A status
    A Catharine Ross
    Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802, USA
    J Nutr 134:269S-275S. 2004
    ..Moreover, retinoid metabolism in the liver is likely to be closely integrated with that in peripheral tissues through the rapid interorgan transfer and recycling of retinoids, affecting the whole-body economy of vitamin A...
  14. ncbi Retinoid production and catabolism: role of diet in regulating retinol esterification and retinoic Acid oxidation
    A Catharine Ross
    Department of Nutritional Sciences, The Pennsylvania State University, University Park 16802, USA
    J Nutr 133:291S-296S. 2003
    ..The regulated expression of LRAT, CYP26 and other genes by RA may provide a sensitive response mechanism that overall serves to adjust the metabolism of vitamin A to maintain retinoid homeostasis and prevent retinoid excess...
  15. pmc Acidic retinoids synergize with vitamin A to enhance retinol uptake and STRA6, LRAT, and CYP26B1 expression in neonatal lung
    Lili Wu
    Department of Nutritional Sciences, Pennsylvania State University, University Park, PA 16802, USA
    J Lipid Res 51:378-87. 2010
    ..However, the pronounced and prolonged induction of CYP26B1 by Am580 may counteract lung RE accumulation after the absorption process is completed...
  16. pmc Lipopolysaccharide opposes the induction of CYP26A1 and CYP26B1 gene expression by retinoic acid in the rat liver in vivo
    Reza Zolfaghari
    Department of Nutritional Sciences, Pennsylvania State University, S 126 Henderson Bldg South, Univ Park, PA 16802, USA
    Am J Physiol Gastrointest Liver Physiol 292:G1029-36. 2007
    ..02) and CYP26B1 (P<0.01). Overall, these results suggest that inflammation can potentially disrupt the balance of RA metabolism and maintenance of RA homeostasis, which may possibly affect the expression of other RA-regulated genes...
  17. doi The 2011 Dietary Reference Intakes for Calcium and Vitamin D: what dietetics practitioners need to know
    A Catharine Ross
    The Pennsylvania State University, University Park, PA, USA
    J Am Diet Assoc 111:524-7. 2011
    ..Urgently needed are evidence-based guidelines to interpret serum 25OHD levels relative to vitamin D status and intervention...
  18. pmc Neonatal-age treatment with vitamin A delays postweaning vitamin A deficiency and increases the antibody response to T-cell dependent antigens in young adult rats fed a vitamin A-deficient diet
    Sandhya Sankaranarayanan
    Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802, USA
    J Nutr 137:1229-35. 2007
    ....
  19. pmc Inflammation induced by lipopolysaccharide does not prevent the vitamin A and retinoic acid-induced increase in retinyl ester formation in neonatal rat lungs
    Lili Wu
    Department of Nutritional Sciences, 110 Chandlee Laboratory, Pennsylvania State University, University Park, PA 16802, USA
    Br J Nutr 109:1739-45. 2013
    ....
  20. pmc An essential set of basic DNA response elements is required for receptor-dependent transcription of the lecithin:retinol acyltransferase (Lrat) gene
    Reza Zolfaghari
    Department of Nutritional Sciences, Pennsylvania State University, University Park, PA 16802, USA
    Arch Biochem Biophys 489:1-9. 2009
    ..Nuclear extracts from RA-treated cells exhibited enhanced binding. Therefore, this proximal region together with basal transcription factors may be sufficient to drive Lrat expression...
  21. pmc Multiple retinoic acid response elements cooperate to enhance the inducibility of CYP26A1 gene expression in liver
    Yao Zhang
    Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802, USA
    Gene 464:32-43. 2010
    ....
  22. pmc Perinatal exposure to vitamin A differentially regulates chondrocyte growth and the expression of aggrecan and matrix metalloprotein genes in the femur of neonatal rats
    Yao Zhang
    Department of Nutritional Sciences, Pennsylvania State University, University Park, PA, USA
    J Nutr 142:649-54. 2012
    ..These results suggest that moderately high maternal VA intake combined with neonatal VARA supplementation can reduce the ratio of aggrecan:MMP, which may unfavorably alter early bone development...
  23. pmc Vitamin A and immune function: retinoic acid modulates population dynamics in antigen receptor and CD38-stimulated splenic B cells
    Qiuyan Chen
    Department of Nutritional Sciences and Huck Institute for Life Sciences, Pennsylvania State University, University Park, PA 16802, USA
    Proc Natl Acad Sci U S A 102:14142-9. 2005
    ....
  24. pmc Cloning and molecular expression analysis of large and small lecithin:retinol acyltransferase mRNAs in the liver and other tissues of adult rats
    Reza Zolfaghari
    Department of Nutritional Sciences, The Pennsylvania State University, 126 S Henderson Building, University Park, PA 16802, U S A
    Biochem J 368:621-31. 2002
    ..The differential usage of these polyadenylation signals can explain the presence of multiple LRAT mRNA transcripts which are expressed in different tissue-specific patterns...
  25. pmc Retinoic acid promotes mouse splenic B cell surface IgG expression and maturation stimulated by CD40 and IL-4
    Qiuyan Chen
    Department of Nutritional Sciences, The Pennsylvania State University, 126 S Henderson Building, University Park, PA 16802, USA
    Cell Immunol 249:37-45. 2007
    ..Overall, RA can promote B-cell maturation at the population level by increasing the number of sIgG1 and CD138 expressing cells, which may be related to the potentiation of humoral immunity in vivo...
  26. pmc DHRS3, a retinal reductase, is differentially regulated by retinoic acid and lipopolysaccharide-induced inflammation in THP-1 cells and rat liver
    Reza Zolfaghari
    Department of Nutritional Sciences, Pennsylvania State University, University Park, 16802, USA
    Am J Physiol Gastrointest Liver Physiol 303:G578-88. 2012
    ....
  27. pmc Oral vitamin A and retinoic acid supplementation stimulates antibody production and splenic Stra6 expression in tetanus toxoid-immunized mice
    Libo Tan
    Graduate Program in Nutrition, Pennsylvania State University, University Park, PA, USA
    J Nutr 142:1590-5. 2012
    ..Concomitantly, these treatments increased the systemic antigen-specific antibody response. The ability of oral retinoids to stimulate systemic immunity has implications for public health and therapeutic use of VA...
  28. pmc Retinoic acid regulates CD1d gene expression at the transcriptional level in human and rodent monocytic cells
    Qiuyan Chen
    Department of Nutritional Sciences, Pennsylvania State University, 126 S Henderson Building, University Park, PA 16802, USA
    Exp Biol Med (Maywood) 232:488-94. 2007
    ..These studies together provide evidence for a previously unknown mechanism of CD1d gene expression regulation by RA and suggest that RA is a significant modulator of NKT cell activation...
  29. ncbi Cloning of rat cytochrome P450RAI (CYP26) cDNA and regulation of its gene expression by all-trans-retinoic acid in vivo
    Yuanping Wang
    Program in Integrative Biosciences, Pennsylvania State University, University Park, PA 16802, USA
    Arch Biochem Biophys 401:235-43. 2002
    ....
  30. pmc Retinoic acid and α-galactosylceramide differentially regulate B cell activation in vitro and augment antibody production in vivo
    Qiuyan Chen
    Department of Nutritional Sciences, Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Clin Vaccine Immunol 18:1015-20. 2011
    ..The results suggest that the combination of RA and αGalCer could be a useful adjuvant combination in vaccine strategies...
  31. pmc Galactomutarotase and other galactose-related genes are rapidly induced by retinoic acid in human myeloid cells
    Tongkun Pai
    Department of Nutritional Sciences, Graduate Program in Nutrition, and Huck Institute for Life Sciences, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Biochemistry 46:15198-207. 2007
    ....
  32. pmc Toll-like receptor 3 ligand and retinoic acid enhance germinal center formation and increase the tetanus toxoid vaccine response
    Yifan Ma
    Department of Nutritional Sciences and Huck Institute for the Life Sciences, Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Clin Vaccine Immunol 16:1476-84. 2009
    ....
  33. ncbi Lecithin:retinol acyltransferase expression is regulated by dietary vitamin A and exogenous retinoic acid in the lung of adult rats
    Reza Zolfaghari
    Department of Nutrition, The Pennsylvania State University, University Park, PA 16802, USA
    J Nutr 132:1160-4. 2002
    ..These results suggest that the regulated storage of vitamin A may be important for maintaining the integrity and physiologic functions of the lung...
  34. pmc Cloning, gene organization and identification of an alternative splicing process in lecithin:retinol acyltransferase cDNA from human liver
    Reza Zolfaghari
    Department of Nutritional Sciences, and Huck Life Science Institute, S 126 Henderson Building, The Pennsylvania State University, University Park, PA 16802, USA
    Gene 341:181-8. 2004
    ....
  35. pmc All-trans-retinoic acid distribution and metabolism in vitamin A-marginal rats
    Christopher J Cifelli
    Department of Nutritional Sciences, Pennsylvania State University, PA 16802, USA
    Am J Physiol Gastrointest Liver Physiol 291:G195-202. 2006
    ..Thus we conclude that RA and LPS act independently to alter RA metabolism in vitamin A-marginal rats...
  36. pmc Retinoic acid regulates cell cycle progression and cell differentiation in human monocytic THP-1 cells
    Qiuyan Chen
    Department of Nutritional Sciences and Huck Institute for Life Sciences, Pennsylvania State University, University Park, PA 16802, USA
    Exp Cell Res 297:68-81. 2004
    ..The multiple effects of RA on cell cycle progression may help to explain its well-documented ability to induce the differentiation of THP-1 cells, and thereby to enhance macrophage-like immune functions...
  37. pmc Ligand activation of peroxisome proliferator-activated receptor-beta/delta inhibits cell proliferation in human HaCaT keratinocytes
    Michael G Borland
    Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, 312 Life Science Building, University Park, PA 16802, USA
    Mol Pharmacol 74:1429-42. 2008
    ....
  38. pmc The anti-tetanus immune response of neonatal mice is augmented by retinoic acid combined with polyriboinosinic:polyribocytidylic acid
    Yifan Ma
    Graduate Program in Integrative Biosciences, Huck Institute for Life Sciences, Pennsylvania State University, University Park, PA 16802, USA
    Proc Natl Acad Sci U S A 102:13556-61. 2005
    ..Thus, RA combined with PIC, a nutritional-immunological intervention, seems promising as an adjuvant for early-life vaccination...
  39. pmc All-trans-retinoic acid and Erk1/2 signaling synergistically regulate the expression of CD300B in human monocytic cells
    Yong Wu
    Department of Nutritional Sciences, Pennsylvania State University, University Park, PA 16802, USA
    Cell Immunol 268:68-78. 2011
    ....
  40. pmc Vitamin A and retinoic acid in the regulation of B-cell development and antibody production
    A Catharine Ross
    Department of Nutritional Sciences, Pennsylvania State University, University Park, Pennsylvania, USA
    Vitam Horm 86:103-26. 2011
    ..Taken together, RA could be a useful component in vaccine strategies and/or for immunotherapy...
  41. pmc Retinoic acid combined with vitamin A synergizes to increase retinyl ester storage in the lungs of newborn and dexamethasone-treated neonatal rats
    A Catharine Ross
    Department of Nutritional Sciences and Huck Institute for Life Sciences, Pennsylvania State University, University Park, PA 16802, USA
    Neonatology 92:26-32. 2007
    ..We previously showed that the nutrient-metabolite combination VARA (molar ratio 10 vitamin A to 1 RA), synergistically increased REs in the lungs of 1-week-old rats, compared to vitamin A or RA alone...
  42. pmc Immunization with pneumococcal polysaccharide serotype 3 and lipopolysaccharide modulates lung and liver inflammation during a virulent Streptococcus pneumoniae infection in mice
    Katherine H Restori
    Graduate Program in Immunology and Infectious Disease, The Huck Institute of Life Sciences, Pennsylvania State University, University Park, Pennsylvania, USA
    Clin Vaccine Immunol 20:639-50. 2013
    ....
  43. pmc Retinoic acid exerts dual regulatory actions on the expression and nuclear localization of interferon regulatory factor-1
    Xin M Luo
    Department of Nutritional Sciences, 126 S Henderson Building, University Park, PA 16802, USA
    Exp Biol Med (Maywood) 231:619-31. 2006
    ....
  44. ncbi Recent advances in molecular cloning of fatty acid desaturase genes and the regulation of their expression by dietary vitamin A and retinoic acid
    Reza Zolfaghari
    Department of Nutritional Sciences, The Pennsylvania State University, 126 S Henderson Building, University Park, PA 16802, USA
    Prostaglandins Leukot Essent Fatty Acids 68:171-9. 2003
    ..The reaction products of these desaturases serve as critical regulators in a wide range of physiological processes which include fetal growth and development, reproduction, cell differentiation, immune and inflammatory responses...
  45. pmc Physiological and receptor-selective retinoids modulate interferon gamma signaling by increasing the expression, nuclear localization, and functional activity of interferon regulatory factor-1
    Xin M Luo
    Department of Nutritional Sciences, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    J Biol Chem 280:36228-36. 2005
    ..These results suggest that atRA, an RARalpha ligand, regulates IFNgamma-induced IRF-1 by affecting multiple components of the IFNgamma signaling pathway, from the plasma membrane to the nuclear transcription factors...
  46. pmc Retinoic acid and polyriboinosinic:polyribocytidylic acid stimulate robust anti-tetanus antibody production while differentially regulating type 1/type 2 cytokines and lymphocyte populations
    Yifan Ma
    Integrative Biosciences Nutritional Sciences Program, Department of Nutritional Sciences, and Huck Institute for the Life Sciences, Pennsylvania State University, University Park, PA 16801, USA
    J Immunol 174:7961-9. 2005
    ..The robust, durable, and proportionate increase in all anti-TT IgG isotypes induced by RA + PIC suggests that this combination is promising as a means to enhance the Ab response to TT and similar vaccines...
  47. pmc Vitamin A supplementation and retinoic acid treatment in the regulation of antibody responses in vivo
    A Catharine Ross
    Department of Nutritional Sciences and Huck Institute for Life Sciences, Pennsylvania State University, University Park, Pennsylvania 16802, USA
    Vitam Horm 75:197-222. 2007
    ....
  48. pmc Retinoic acid and the transcription factor MafB act together and differentially to regulate aggrecan and matrix metalloproteinase gene expression in neonatal chondrocytes
    Yao Zhang
    Department of Nutritional Sciences, Pennsylvania State University, University Park, PA 16802, USA
    J Cell Biochem 114:471-9. 2013
    ..These results support a role for MafB as a regulator of chondrocyte gene expression and matrix formation via control of aggrecan, MMP3 and MMP13 expression, and indicate an important role for RA in the regulation of MafB...
  49. pmc Application of a key events dose-response analysis to nutrients: a case study with vitamin A (retinol)
    A Catharine Ross
    Department of Nutritional Sciences, Pennsylvania State University, University Park, PA, USA
    Crit Rev Food Sci Nutr 49:708-17. 2009
    ....
  50. pmc Liver-specific cytochrome P450 CYP2C22 is a direct target of retinoic acid and a retinoic acid-metabolizing enzyme in rat liver
    Linxi Qian
    Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802, USA
    J Lipid Res 51:1781-92. 2010
    ..Our studies demonstrate that CYP2C22 is a high-abundance, retinoid-inducible, hepatic P450 with the potential to metabolize at-RA, providing additional insight into the role of the CYP2C gene family in retinoid homeostasis...
  51. pmc Opposing cytokine-specific effects of all trans-retinoic acid on the activation and expression of signal transducer and activator of transcription (STAT)-1 in THP-1 cells
    Qiuyan Chen
    Department of Nutritional Sciences, The Pennsylvania State University, 126 S Henderson Building, University Park, PA 16802, USA
    Immunology 107:199-208. 2002
    ..These results imply that RA can significantly rebalance STAT-1-dependent responses, and that one of the mechanisms may be through the inhibition of the NFkappaB pathway...
  52. doi All-trans-retinoic acid and the glycolipid α-galactosylceramide combined reduce breast tumor growth and lung metastasis in a 4T1 murine breast tumor model
    Qiuyan Chen
    Department of Nutritional Sciences, Pennsylvania State University, University Park, Pennsylvania, USA
    Nutr Cancer 64:1219-27. 2012
    ....
  53. pmc Lipid emulsion administered intravenously or orally attenuates triglyceride accumulation and expression of inflammatory markers in the liver of nonobese mice fed parenteral nutrition formula
    Kyoko Ito
    Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA, USA
    J Nutr 143:253-9. 2013
    ..In summary, LE given either i.v. or orally may be sufficient to reduce the steatotic potential of orally fed high-dextrose formulas and may suppress the early development of HS during PN therapy...
  54. pmc Chronic vitamin A status and acute repletion with retinyl palmitate are determinants of the distribution and catabolism of all-trans-retinoic acid in rats
    Christopher J Cifelli
    Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802, USA
    J Nutr 137:63-70. 2007
    ....
  55. pmc Diet in vitamin A research
    A Catharine Ross
    Department of Nutritional Sciences and Huck Institute for the Life Sciences, Pennsylvania State University, University Park, PA 16802, USA
    Methods Mol Biol 652:295-313. 2010
    ....
  56. doi Retinoic acid and α-galactosylceramide regulate the expression of costimulatory receptors and transcription factors responsible for B cell activation and differentiation
    Qiuyan Chen
    Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802, United States
    Immunobiology 218:1477-87. 2013
    ..Together, our data demonstrate that RA and αGalCer can regulate B cell activation and differentiation at multiple levels in a complementary manner, facilitating the progress of B cells towards antibody secreting cells...
  57. pmc Cortical and trabecular bone, bone mineral density, and resistance to ex vivo fracture are not altered in response to life-long vitamin A supplementation in aging rats
    Amanda E Wray
    Department of Nutritional Sciences, The Pennsylvania State University, University Park, PA 16802, USA
    J Nutr 141:660-6. 2011
    ..From these results, we conclude that VA-marginal status affects trabecular bone more than cortical bone, and VA supplementation at a moderate level over the lifetime is unlikely to increase the risk of age-related bone fracture in rats...
  58. ncbi Iron deficiency and marginal vitamin A deficiency affect growth, hematological indices and the regulation of iron metabolism genes in rats
    Yi Ning J Strube
    The Graduate Program in Nutrition and the Department of Nutritional Sciences, The Pennsylvania State University, University Park 16802, USA
    J Nutr 132:3607-15. 2002
    ..These results are consistent with an impaired mobilization of liver retinol during iron deficiency as well as multiple alterations in iron metabolism...
  59. ncbi Retinoic acid therapy attenuates the severity of tuberculosis while altering lymphocyte and macrophage numbers and cytokine expression in rats infected with Mycobacterium tuberculosis
    Hiroyuki Yamada
    Mycobacterial Reference Center, Research Institute of Tuberculosis, Tokyo 204 0022 Japan
    J Nutr 137:2696-700. 2007
    ..To our knowledge, this is the first reported study to demonstrate that orally administered RA significantly inhibits the in vivo growth of M. tuberculosis and the development of tuberculosis...
  60. ncbi On the sources of retinoic acid in the lung: understanding the local conversion of retinol to retinoic acid
    A Catharine Ross
    Am J Physiol Lung Cell Mol Physiol 286:L247-8. 2004
  61. pmc Profile of A. Catharine Ross
    Bijal Trivedi
    Proc Natl Acad Sci U S A 102:14139-41. 2005
  62. ncbi Retinol equivalency ratio of beta-carotene
    Robert M Russell
    J Nutr 133:2915-6; author reply 2917. 2003
  63. ncbi Retinol-binding protein, transthyretin, and C-reactive protein in extremely low birth weight (ELBW) infants
    Namasivayam Ambalavanan
    Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35246, USA
    J Perinatol 25:714-9. 2005
    ..Vitamin A deficiency reduces retinol binding protein (RBP) but not transthyretin (TTR), while inflammation reduces both RBP and TTR and increases C-reactive protein (CRP), an acute phase reactant...
  64. ncbi Proteomic analysis of rat plasma by two-dimensional liquid chromatography and matrix-assisted laser desorption ionization time-of-flight mass spectrometry
    Thomas Linke
    Phytonutrients Laboratory, Beltsville Human Nutrition Research Center, BARC East, Beltsville, MD 20705, USA
    J Chromatogr A 1123:160-9. 2006
    ..Quantitative proteomic analysis of complex samples such as plasma is still a difficult task. We discuss the potential of this approach for biomarker discovery and address the experimental challenges that remain...
  65. ncbi Profiling of rat plasma by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry, a novel tool for biomarker discovery in nutrition research
    Thomas Linke
    Phytonutrients Laboratory, Beltsville Human Nutrition Research Center, BARC East, Beltsville, MD 20705, USA
    J Chromatogr A 1043:65-71. 2004
    ..These results demonstrate that plasma profiling by anion-exchange fractionation and SELDI-TOF-MS may be a promising surveillance tool to detect changes in nutritional status and whole body physiology...
  66. ncbi 2,3,7,8-tetrachlorodibenzo-p-dioxin induces lecithin: retinol acyltransferase transcription in the rat kidney
    Pi Hoegberg
    Institute of Environmental Medicine, Karolinska Institutet, P O Box 210, S 17177 Stockholm, Sweden
    Chem Biol Interact 145:1-16. 2003
    ....

Research Grants27

  1. RETINOID NUTRITIONAL STATUS AND IMMUNE FUNCTION
    A Ross; Fiscal Year: 2005
    ..abstract_text> ..
  2. MOLECULAR REGULATION OF LRAT AND CYP26 IN LIVER
    A Ross; Fiscal Year: 2005
    ..This information could shed new light on the endogenous factors that control the availability of Retinoic acid in tissues and plasma which, in turn, are likely to affect Retinoic acid's anticarcinogenic potential. ..
  3. RETINOID NUTRITIONAL STATUS AND IMMUNE FUNCTION
    A Ross; Fiscal Year: 2007
    ....
  4. Molecular Regulation of LRAT and CYP26 in Lung and Liver
    A Ross; Fiscal Year: 2009
    ....
  5. RETINOID NUTRITIONAL STATUS AND IMMUNE FUNCTION
    A Ross; Fiscal Year: 2009
    ....
  6. Molecular Regulation of LRAT and CYP26 in Lung and Liver
    A Catharine Ross; Fiscal Year: 2010
    ....
  7. RETINOID NUTRITIONAL STATUS AND IMMUNE FUNCTION
    A Catharine Ross; Fiscal Year: 2010
    ....
  8. Vitamin A Supplementation and Retinol Metabolism in the Neonatal Period
    A Catharine Ross; Fiscal Year: 2010
    ..The evidence from these studies will help to inform U.S. dietary recommendations for infants, international VA supplementation policy, and clinical treatment of neonatal lung disease. ..
  9. RETINOID NUTRITIONAL STATUS AND IMMUNE FUNCTION
    A Ross; Fiscal Year: 2002
    ....
  10. RETINOID NUTRITIONAL STATUS AND IMMUNE FUNCTION
    A Catharine Ross; Fiscal Year: 2010
    ....