Ozdemir T, Xu L, SIEDLECKI C, Brown J. Substrate curvature sensing through Myosin IIa upregulates early osteogenesis. Integr Biol (Camb). 2013;5:1407-16 pubmed publisher
..Our results shed light on mechanisms underlying geometry sensing by highlighting the role of Myosin IIa in addition to ROCKII and could ultimately contribute to scaffold design strategies. ..
Higgins A, Banik B, Brown J. Geometry sensing through POR1 regulates Rac1 activity controlling early osteoblast differentiation in response to nanofiber diameter. Integr Biol (Camb). 2015;7:229-36 pubmed publisher
..Thus, POR1 senses curvature and increases Rac1 activity, which negatively regulates bone differentiation. ..