Research Topics
| Timothy MosherSummaryAffiliation: Pennsylvania State University Country: USA Publications
Research Grants
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Detail Information
Publications
Change in knee cartilage T2 at MR imaging after running: a feasibility studyTimothy J Mosher
Pennsylvania State University Center for NMR Research, Department of Radiology, Milton S Hershey Medical Center, 500 University Drive, Hershey, PA 17033, USA
Radiology 234:245-9. 2005..These in vivo observations agree well with published ex vivo results and support the hypothesis that cartilage compression results in greater anisotropy of superficial collagen fibers...
1H magnetic resonance spectroscopy of nanomelic chicken cartilage: effect of aggrecan depletion on cartilage T2T J Mosher
Penn State Center for NMR Research, Department of Radiology, The Penn State University College of Medicine, Hershey, PA 17033, USA
Osteoarthritis Cartilage 11:709-15. 2003..To determine the effect of proteoglycan depletion on cartilage proton magnetic resonance (MR) spectroscopy T2 using nanomelic chicken cartilage, a genetic mutant that completely lacks aggrecan...
Effect of gender on in vivo cartilage magnetic resonance imaging T2 mappingTimothy J Mosher
Penn State Center for NMR Research, Department of Radiology, Penn State University College of Medicine, Hershey, Pennsylvania 17033, USA
J Magn Reson Imaging 19:323-8. 2004..To determine if gender is a significant variable for in vivo magnetic resonance imaging (MRI) T2-mapping of knee articular cartilage in young asymptomatic volunteers...
Functional cartilage MRI T2 mapping: evaluating the effect of age and training on knee cartilage response to runningT J Mosher
Penn State Center for NMR Research, Department of Radiology, The Penn State Milton S Hershey Medical Center, Hershey, PA 17033, USA
Osteoarthritis Cartilage 18:358-64. 2010..To characterize effects of age and physical activity level on cartilage thickness and T2 response immediately after running...
Imaging of rheumatoid arthritis: can MR imaging be used to monitor cellular response of disease?Timothy J Mosher
Department of Radiology, MC H066, Milton S Hershey Medical Center, 500 University Dr, Hershey, PA 17033, USA
Radiology 233:1-2. 2004
Age dependency of cartilage magnetic resonance imaging T2 relaxation times in asymptomatic womenTimothy J Mosher
Pennsylvania State University, Milton S Hershey Medical Center, Hershey, Pennsylvania 17033, USA
Arthritis Rheum 50:2820-8. 2004..The purpose of this study was to determine age-dependent differences in cartilage T2 values in healthy asymptomatic women...
MRI of osteochondral injuries of the knee and ankle in the athleteTimothy J Mosher
Department of Radiology, MC H066, Pennsylvania State University Milton S. Hershey Medical Center, 500 University Drive, Hershey, PA 17033, USA
Clin Sports Med 25:843-66. 2006
Knee articular cartilage damage in osteoarthritis: analysis of MR image biomarker reproducibility in ACRIN-PA 4001 multicenter trialTimothy J Mosher
Department of Radiology, Penn State University College of Medicine, Penn State University Hospital, 500 University Dr, Hershey, PA 17033, USA
Radiology 258:832-42. 2011....
Musculoskeletal imaging at 3T: current techniques and future applicationsTimothy J Mosher
Department of Radiology, Penn State Milton S Hershey Medical Center, Hershey, PA 17033, USA
Magn Reson Imaging Clin N Am 14:63-76. 2006..In addition to clinical application, 3T MR imaging has an important role for furthering translational research in MSK diseases through the development of new molecular and functional MR imaging techniques...
High prevalence of pelvic and hip magnetic resonance imaging findings in asymptomatic collegiate and professional hockey playersMatthew L Silvis
Pennsylvania State Milton S Hershey Medical Center, 17033, USA
Am J Sports Med 39:715-21. 2011..The true prevalence of these findings and association with symptoms in this population is unknown...
Interphalangeal joint cartilage: high-spatial-resolution in vivo MR T2 mapping--a feasibility studyJelena Lazovic-Stojkovic
Department of Radiology, Pennsylvania State University Center for NMR Research, Penn State Milton S. Hershey Medical Center, 500 University Dr, Hershey, PA 17033, USA
Radiology 233:292-6. 2004..Application of T2 mapping techniques to non-weight-bearing joints may provide a means for differentiation of local biomechanical and systemic factors that can affect cartilage T2 values...
Attenuation of arthritis in rodents by a novel orally-available inhibitor of sphingosine kinaseLeo R Fitzpatrick
Department of Pharmacology, Penn State College of Medicine, Hershey, Hummelstown, PA 17036, USA
Inflammopharmacology 19:75-87. 2011..Pro-inflammatory cytokines like TNF-α activate sphingosine kinase (SK). Therefore, inhibition of SK is a potential molecular target for the treatment of rheumatoid arthritis...
Cartilage MRI T2 relaxation time mapping: overview and applicationsTimothy J Mosher
Department of Radiology, The Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania 17033, USA
Semin Musculoskelet Radiol 8:355-68. 2004....
Diagnostic effectiveness of gadolinium-enhanced MR imaging in evaluation of abnormal bone marrow signalTimothy J Mosher
Radiology 224:320-2. 2002
Research Grants
- MRI T2 Mapping of Cartilage for Diagnosis of Early OATimothy Mosher; Fiscal Year: 2003....
