Gráinne H Long

Summary

Affiliation: Pennsylvania State University
Country: USA

Publications

  1. pmc Experimental manipulation of immune-mediated disease and its fitness costs for rodent malaria parasites
    Gráinne H Long
    Institutes of Evolution, Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, King s Buildings, West Mains Road, Edinburgh, EH9 3JT, UK
    BMC Evol Biol 8:128. 2008
  2. doi request reprint Blockade of TNF receptor 1 reduces disease severity but increases parasite transmission during Plasmodium chabaudi chabaudi infection
    Gráinne H Long
    Institutes of Evolution, Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JT, Scotland, UK
    Int J Parasitol 38:1073-81. 2008
  3. pmc Dynamic models of immune responses: what is the ideal level of detail?
    Juilee Thakar
    Center for Infectious Disease Dynamics and Department of Physics, Pennsylvania State University, University Park, PA 16802, USA
    Theor Biol Med Model 7:35. 2010

Detail Information

Publications3

  1. pmc Experimental manipulation of immune-mediated disease and its fitness costs for rodent malaria parasites
    Gráinne H Long
    Institutes of Evolution, Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, King s Buildings, West Mains Road, Edinburgh, EH9 3JT, UK
    BMC Evol Biol 8:128. 2008
    ..Here we studied the effects of immunopathology on infection-induced host mortality rate and lifetime transmission potential - key components of parasite fitness - using the rodent malaria model, Plasmodium chabaudi chabaudi...
  2. doi request reprint Blockade of TNF receptor 1 reduces disease severity but increases parasite transmission during Plasmodium chabaudi chabaudi infection
    Gráinne H Long
    Institutes of Evolution, Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JT, Scotland, UK
    Int J Parasitol 38:1073-81. 2008
    ..These results suggest that the effects of candidate malaria interventions on infectivity should be examined alongside effects on disease severity so that the epidemiological consequences of such interventions can be evaluated...
  3. pmc Dynamic models of immune responses: what is the ideal level of detail?
    Juilee Thakar
    Center for Infectious Disease Dynamics and Department of Physics, Pennsylvania State University, University Park, PA 16802, USA
    Theor Biol Med Model 7:35. 2010
    ..Dynamic models constructed to study the interactions between pathogens and hosts' immune responses have revealed key regulatory processes in the infection...