JOSHUA LAMBERT

Summary

Affiliation: Pennsylvania State University
Country: USA

Publications

  1. ncbi request reprint Avocado (Persea americana) seed as a source of bioactive phytochemicals
    Deepti Dabas
    Department of Food Science, The Pennsylvania State University, 332 Food Science Building, University Park, PA 16802
    Curr Pharm Des 19:6133-40. 2013
  2. ncbi request reprint The cancer preventive effects of edible mushrooms
    Tongtong Xu
    Center of Excellence for Plant and Mushroom Foods for Health, Department of Food Science, The Pennsylvania State University, University Park, PA 16802, USA
    Anticancer Agents Med Chem 12:1255-63. 2012
  3. doi request reprint A colored avocado seed extract as a potential natural colorant
    Deepti Dabas
    Dept of Food Science, The Pennsylvania State Univ, Univ Park, PA 16802, USA
    J Food Sci 76:C1335-41. 2011
  4. pmc Inhibition of lung cancer growth in mice by dietary mixed tocopherols
    Joshua D Lambert
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ, USA
    Mol Nutr Food Res 53:1030-5. 2009
  5. pmc Effect of genistein on the bioavailability and intestinal cancer chemopreventive activity of (-)-epigallocatechin-3-gallate
    Joshua D Lambert
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
    Carcinogenesis 29:2019-24. 2008
  6. pmc Anticancer and anti-inflammatory effects of cysteine metabolites of the green tea polyphenol, (-)-epigallocatechin-3-gallate
    Joshua D Lambert
    Department of Food Science, The Pennsylvania State University, 332 Food Science Building, University Park, Pennsylvania 16802, USA
    J Agric Food Chem 58:10016-9. 2010
  7. pmc The antioxidant and pro-oxidant activities of green tea polyphenols: a role in cancer prevention
    Joshua D Lambert
    Department of Food Science, The Pennsylvania State University, University Park, PA 16802, USA
    Arch Biochem Biophys 501:65-72. 2010
  8. pmc Hepatotoxicity of high oral dose (-)-epigallocatechin-3-gallate in mice
    Joshua D Lambert
    Department of Food Science, The Pennsylvania State University, 332 Food Science Building, University Park, PA 16802, USA
    Food Chem Toxicol 48:409-16. 2010
  9. pmc Antioxidative and anti-carcinogenic activities of tea polyphenols
    Chung S Yang
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, 164 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Arch Toxicol 83:11-21. 2009
  10. ncbi request reprint Mechanisms of cancer prevention by tea constituents
    Joshua D Lambert
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
    J Nutr 133:3262S-3267S. 2003

Collaborators

  • Chung Yang
  • S Sang
  • Hang Xiao
  • Robert Dorr
  • Yong Lin
  • Jihyeung Ju
  • Deepti Dabas
  • Mousumi Bose
  • Xingpei Hao
  • Mao Jung Lee
  • Kimberly A Grove
  • Gang Lu
  • Gregory R Ziegler
  • Tongtong Xu
  • Sudathip Sae-Tan
  • Ali Husain
  • Sunny Park
  • Dapeng Chen
  • Zhe Hou
  • Jungil Hong
  • Rachel M Shegog
  • Robert B Beelman
  • Mary J Kennett
  • Ryan J Elias
  • Harold L Newmark
  • Kenneth R Reuhl
  • Sue A Shapses
  • Yuhai Sun
  • Steven Wang
  • William J Welsh
  • Ching Y Wang
  • Ni Ai
  • Hong Lu
  • Xiaofeng Meng
  • Saileta Prabhu
  • Pius Maliakal
  • Chi Tang Ho
  • Khew Voon Chin
  • Sung Hack Lee
  • Patrick J Sinko

Detail Information

Publications46

  1. ncbi request reprint Avocado (Persea americana) seed as a source of bioactive phytochemicals
    Deepti Dabas
    Department of Food Science, The Pennsylvania State University, 332 Food Science Building, University Park, PA 16802
    Curr Pharm Des 19:6133-40. 2013
    ..Here, we review the currently-available data on the bioactivity and other functional properties of avocado seeds. We discuss the strength of the available data, the putative active compounds, and potential directions for future studies. ..
  2. ncbi request reprint The cancer preventive effects of edible mushrooms
    Tongtong Xu
    Center of Excellence for Plant and Mushroom Foods for Health, Department of Food Science, The Pennsylvania State University, University Park, PA 16802, USA
    Anticancer Agents Med Chem 12:1255-63. 2012
    ..The results of animal model and human intervention studies, as well as supporting in vitro mechanistic studies are critically evaluated. Weaknesses in the current data and topics for future work are highlighted...
  3. doi request reprint A colored avocado seed extract as a potential natural colorant
    Deepti Dabas
    Dept of Food Science, The Pennsylvania State Univ, Univ Park, PA 16802, USA
    J Food Sci 76:C1335-41. 2011
    ..The color was found to be stable in solution at -18 °C for 2 mo. These results suggest that the avocado seed may be a potential source of natural colorant, and that color development is PPO-dependent...
  4. pmc Inhibition of lung cancer growth in mice by dietary mixed tocopherols
    Joshua D Lambert
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ, USA
    Mol Nutr Food Res 53:1030-5. 2009
    ..Further studies are needed to determine the underlying mechanisms for this anticancer activity, and to determine if such activity occurs in other models of cancer...
  5. pmc Effect of genistein on the bioavailability and intestinal cancer chemopreventive activity of (-)-epigallocatechin-3-gallate
    Joshua D Lambert
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
    Carcinogenesis 29:2019-24. 2008
    ..These results further show the need for careful cancer prevention studies in animal models and for caution when interpreting data from in vitro studies...
  6. pmc Anticancer and anti-inflammatory effects of cysteine metabolites of the green tea polyphenol, (-)-epigallocatechin-3-gallate
    Joshua D Lambert
    Department of Food Science, The Pennsylvania State University, 332 Food Science Building, University Park, Pennsylvania 16802, USA
    J Agric Food Chem 58:10016-9. 2010
    ..These results remain to be confirmed in vivo...
  7. pmc The antioxidant and pro-oxidant activities of green tea polyphenols: a role in cancer prevention
    Joshua D Lambert
    Department of Food Science, The Pennsylvania State University, University Park, PA 16802, USA
    Arch Biochem Biophys 501:65-72. 2010
    ..This review is meant point out understudied areas and stimulate research on the topic with the hope that insights into the mechanisms of cancer preventive activity of tea polyphenols will result...
  8. pmc Hepatotoxicity of high oral dose (-)-epigallocatechin-3-gallate in mice
    Joshua D Lambert
    Department of Food Science, The Pennsylvania State University, 332 Food Science Building, University Park, PA 16802, USA
    Food Chem Toxicol 48:409-16. 2010
    ....
  9. pmc Antioxidative and anti-carcinogenic activities of tea polyphenols
    Chung S Yang
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, 164 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Arch Toxicol 83:11-21. 2009
    ..Finally, we discuss the effects of tea consumption on cancer risk in humans. It is our aim to raise some of the unanswered questions regarding cancer prevention by tea and to stimulate further research in this area...
  10. ncbi request reprint Mechanisms of cancer prevention by tea constituents
    Joshua D Lambert
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
    J Nutr 133:3262S-3267S. 2003
    ..Such discussion, it is hoped, will clarify some misunderstandings of cancer prevention by tea and stimulate new research efforts...
  11. pmc N-Acetylcysteine enhances the lung cancer inhibitory effect of epigallocatechin-3-gallate and forms a new adduct
    Joshua D Lambert
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
    Free Radic Biol Med 44:1069-74. 2008
    ..The present results show that under cell culture conditions, EGCG and NAC interact to form a previously unreported adduct, EGCG-2'-NAC, which may contribute to enhancement of EGCG-mediated cell killing...
  12. ncbi request reprint Biotransformation of green tea polyphenols and the biological activities of those metabolites
    Joshua D Lambert
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854, USA
    Mol Pharm 4:819-25. 2007
    ..We hope this article will spark research efforts on some of the important questions regarding tea polyphenol bioavailability, biotransformation, and the biological activities of tea catechin metabolites...
  13. pmc Inhibition of carcinogenesis by tea constituents
    Jihyeung Ju
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854 8020, USA
    Semin Cancer Biol 17:395-402. 2007
    ..Human intervention trials are warranted to determine the possible prevention of cancer of specific sites by preparation of tea constituents...
  14. ncbi request reprint Delivery of tea polyphenols to the oral cavity by green tea leaves and black tea extract
    Mao Jung Lee
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA
    Cancer Epidemiol Biomarkers Prev 13:132-7. 2004
    ..These results indicate that tea leaves can be used as a convenient, slow-release source of catechins and theaflavins and provide information for the possible use of tea in the prevention of oral cancer and dental caries...
  15. ncbi request reprint Cancer chemopreventive activity and bioavailability of tea and tea polyphenols
    Joshua D Lambert
    Department of Chemical Biology, Laboratory for Cancer Research, Rutgers, The State University of New Jersey, 164 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Mutat Res 523:201-8. 2003
    ..We hope this article will spark research efforts on some of the important questions regarding tea polyphenol bioavailability and cancer chemoprevention...
  16. ncbi request reprint Redox properties of tea polyphenols and related biological activities
    Shengmin Sang
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
    Antioxid Redox Signal 7:1704-14. 2005
    ....
  17. ncbi request reprint Inhibition of intestinal tumorigenesis in Apc(min/+) mice by green tea polyphenols (polyphenon E) and individual catechins
    Xingpei Hao
    Department of Chemical Biology, Ernest Mario School of Pharmacy Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
    Nutr Cancer 59:62-9. 2007
    ..The results suggest that these molecular events contribute to the cancer prevention activity of EGCG and PPE. Furthermore, diet appears to be a better route of administration for PPE than drinking fluid...
  18. doi request reprint Bioavailability issues in studying the health effects of plant polyphenolic compounds
    Chung S Yang
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854 8020, USA
    Mol Nutr Food Res 52:S139-51. 2008
    ..Further research on both the biological activity and bioavailability of dietary polyphenols is needed to properly assess their usefulness for the prevention and treatment of disease...
  19. ncbi request reprint Peracetylation as a means of enhancing in vitro bioactivity and bioavailability of epigallocatechin-3-gallate
    Joshua D Lambert
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
    Drug Metab Dispos 34:2111-6. 2006
    ..4- and 6.0-fold, respectively). These data suggest that acetylation represents a means of increasing the biological potency in vitro, increasing the bioavailability of EGCG in vivo, and may improve cancer-preventive activity...
  20. pmc Cancer prevention by tea and tea polyphenols
    Chung S Yang
    Department of Chemical Biology, Ernest Mario School of Phar macy, Rutgers, The State University of New Jersey, 164 Frelinghuysen Road, Piscataway, NJ 08854 8020, USA
    Asia Pac J Clin Nutr 17:245-8. 2008
    ..Human intervention trials and large prospective studies are needed to further assess the cancer preventive activities of tea constituents...
  21. ncbi request reprint Possible controversy over dietary polyphenols: benefits vs risks
    Joshua D Lambert
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854, USA
    Chem Res Toxicol 20:583-5. 2007
  22. ncbi request reprint Effects of tea polyphenols on signal transduction pathways related to cancer chemoprevention
    Zhe Hou
    Susan Lehman Cullman Laboratory for Cancer Research, Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers University, 164 Frelinghuysen Road, Piscataway, NJ 08854 8020, USA
    Mutat Res 555:3-19. 2004
    ..It is likely that multiple signal transduction pathways are involved in the inhibition of carcinogenesis by tea constituents. The relative importance of these pathways needs to be determined in vivo...
  23. ncbi request reprint Synthesis and biological activity of the tea catechin metabolites, M4 and M6 and their methoxy-derivatives
    Joshua D Lambert
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854 8020, USA
    Bioorg Med Chem Lett 15:873-6. 2005
    ..The possible antiinflammatory activity of 1 and its trimethoxy derivative was also evaluated. Neither compound inhibited the release of arachidonic acid, although 1 inhibited NO production by 50% at 20 microM...
  24. ncbi request reprint Molecular targets for the cancer preventive activity of tea polyphenols
    Chung S Yang
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854, USA
    Mol Carcinog 45:431-5. 2006
    ..Validating the related cancer preventive mechanisms found in in vitro studies in animal models and human samples would be exciting...
  25. pmc Tea and cancer prevention: molecular mechanisms and human relevance
    Chung S Yang
    Susan Lehman Cullman Laboratory of Cancer Research, Department of Chemical Biology, and Center for Cancer Prevention Research, The State University of New Jersey, Piscataway, NJ 08854 8020, USA
    Toxicol Appl Pharmacol 224:265-73. 2007
    ..Some interesting examples in this area are discussed...
  26. pmc The major green tea polyphenol, (-)-epigallocatechin-3-gallate, inhibits obesity, metabolic syndrome, and fatty liver disease in high-fat-fed mice
    Mousumi Bose
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
    J Nutr 138:1677-83. 2008
    ..Short-term EGCG treatment appeared to reverse preexisting high-fat-induced metabolic pathologies in obese mice. These effects may be mediated by decreased lipid absorption, decreased inflammation, and other mechanisms...
  27. ncbi request reprint Inhibition of carcinogenesis by polyphenols: evidence from laboratory investigations
    Joshua D Lambert
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, New Jersey, USA
    Am J Clin Nutr 81:284S-291S. 2005
    ....
  28. pmc Laboratory, epidemiological, and human intervention studies show that tea (Camellia sinensis) may be useful in the prevention of obesity
    Kimberly A Grove
    Department of Food Science, The Pennsylvania State University, University Park, PA 16802, USA
    J Nutr 140:446-53. 2010
    ..We hope that this review will expose areas for further study and encourage research on this important public health issue...
  29. ncbi request reprint Inhibition of tumorigenesis in ApcMin/+ mice by a combination of (-)-epigallocatechin-3-gallate and fish oil
    Mousumi Bose
    Susan L Cullman Laboratory for Cancer Research, Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, State University of New Jersey, 164 Frelinghuysen Road, Piscataway, New Jersey 08854 8020, USA
    J Agric Food Chem 55:7695-700. 2007
    ..The results indicate that a combination of low doses of EGCG and fish oil can inhibit tumor multiplicity in Apc (Min/+) mice...
  30. ncbi request reprint Metabolism of dietary polyphenols and possible interactions with drugs
    Joshua D Lambert
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
    Curr Drug Metab 8:499-507. 2007
    ..The potential consequences of these effects on drug metabolism will also be discussed...
  31. ncbi request reprint Epigallocatechin-3-gallate is absorbed but extensively glucuronidated following oral administration to mice
    Joshua D Lambert
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
    J Nutr 133:4172-7. 2003
    ..This is the first report of the pharmacokinetic parameters of EGCG in mice. Such information provides a basis for understanding the bioavailability of EGCG in mice and should aid in understanding the cancer preventive activity of EGCG...
  32. ncbi request reprint Possible mechanisms of the cancer-preventive activities of green tea
    Chung S Yang
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
    Mol Nutr Food Res 50:170-5. 2006
    ..We also need to distinguish between primary and subsequent events. Possible artifacts should be recognized. The cancer-preventive mechanisms need to be validated in animal models or human samples...
  33. ncbi request reprint Synthesis and structure identification of thiol conjugates of (-)-epigallocatechin gallate and their urinary levels in mice
    Shengmin Sang
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, New Jersey 08854 8020, USA
    Chem Res Toxicol 18:1762-9. 2005
    ..These results suggest that detectable amounts of thiol conjugates of EGCG are formed only after rather high doses of EGCG are given to the mice...
  34. ncbi request reprint Enzymatic synthesis of tea theaflavin derivatives and their anti-inflammatory and cytotoxic activities
    Shengmin Sang
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers University, 164 Frelinghuysen Road, Piscataway, NJ 08854 8020, USA
    Bioorg Med Chem 12:459-67. 2004
    ..7 cells. Their cytotoxic activities against KYSE 150 and 510 human esophageal squamous cell carcinoma and HT 29 human colon cancer cells were also evaluated...
  35. ncbi request reprint Cancer chemoprevention by targeting proteasomal degradation: commentary re KA Dragnev et al, Specific chemopreventive agents trigger proteasomal degradation of G1 cyclins: implications for combination therapy. Clin Cancer Res, 2004;10:2570-7
    Chung S Yang
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA
    Clin Cancer Res 10:2220-1. 2004
  36. ncbi request reprint Piperine enhances the bioavailability of the tea polyphenol (-)-epigallocatechin-3-gallate in mice
    Joshua D Lambert
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, State University of New Jersey, Piscataway, NJ 08854, USA
    J Nutr 134:1948-52. 2004
    ..The present study demonstrates the modulation of the EGCG bioavailablity by a second dietary component and illustrates a mechanism for interactions between dietary chemicals...
  37. ncbi request reprint Dose-dependent levels of epigallocatechin-3-gallate in human colon cancer cells and mouse plasma and tissues
    Joshua D Lambert
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, NJ 08854 8020, USA
    Drug Metab Dispos 34:8-11. 2006
    ..The present study provides information with respect to what concentrations of EGCG are achievable in mice and may guide dose selection for future cancer chemoprevention studies with EGCG...
  38. ncbi request reprint Inhibition of human liver catechol-O-methyltransferase by tea catechins and their metabolites: structure-activity relationship and molecular-modeling studies
    Dapeng Chen
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers University, 164 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Biochem Pharmacol 69:1523-31. 2005
    ..These results provide mechanistic insight into the inhibition of COMT by commonly consumed tea catechins...
  39. ncbi request reprint Salivary hydrogen peroxide produced by holding or chewing green tea in the oral cavity
    Joshua D Lambert
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway NJ 08854, USA
    Free Radic Res 41:850-3. 2007
    ..2 microM). Salivary H(2)O(2) and catechin concentrations were similar to those that are biologically active in vitro. Catechin-generated H(2)O(2) may, therefore, have a role in disease prevention by green tea...
  40. ncbi request reprint Transdermal delivery of (-)-epigallocatechin-3-gallate, a green tea polyphenol, in mice
    Joshua D Lambert
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
    J Pharm Pharmacol 58:599-604. 2006
    ..These data indicate that transdermal EGCG is useful for delivering prolonged levels of EGCG to plasma and tissues, and may provide an alternative to tea consumption as a dosage form of EGCG...
  41. pmc (-)-Epigallocatechin-3-gallate increases the expression of genes related to fat oxidation in the skeletal muscle of high fat-fed mice
    Sudathip Sae-Tan
    Department of Food Science, The Pennsylvania State University, 332 Food Science Building, University Park, PA 16802, USA
    Food Funct 2:111-6. 2011
    ..In summary, it appears that EGCG modulates body weight gain in high fat-fed mice both by increasing the expression of genes related fat oxidation in the skeletal muscle and by modulating fat absorption from the diet...
  42. ncbi request reprint Involvement of multidrug resistance-associated proteins in regulating cellular levels of (-)-epigallocatechin-3-gallate and its methyl metabolites
    Jungil Hong
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA
    Biochem Biophys Res Commun 310:222-7. 2003
    ..The results indicate that EGCG and its methyl metabolites are substrates for MRP1 and MRP2, but not for Pgp. MRP type efflux pumps may limit the bioavailability of EGCG...
  43. ncbi request reprint Cytotoxic lignans from Larrea tridentata
    Joshua D Lambert
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, 164 Frelinghuysen Road, Piscataway, NJ 08854, USA
    Phytochemistry 66:811-5. 2005
    ..The relative potency of linear butane type lignans against human breast cancer appears to correlate positively with the number of O-methyl groups present on the molecule...
  44. ncbi request reprint Benzotropolone inhibitors of estradiol methylation: kinetics and in silico modeling studies
    Joshua D Lambert
    Department of Chemical Biology Rutgers, Ernest Mario School of Pharmacy, The State University of New Jersey, 164 Frelinghuysen Rd, Piscataway, NJ 08854, USA
    Bioorg Med Chem 13:2501-7. 2005
    ..Further studies are needed to determine the impact in vivo of COMT inhibition by these compounds...
  45. ncbi request reprint Wheat bran oil and its fractions inhibit human colon cancer cell growth and intestinal tumorigenesis in Apc(min/+) mice
    Shengmin Sang
    Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers University, 164 Frelinghuysen Road, Piscataway, New Jersey 08854 8020, USA
    J Agric Food Chem 54:9792-7. 2006
    ..The current results demonstrate, for the first time, the intestinal cancer preventive activity of WB oil. The active ingredients, however, remain to be identified...
  46. pmc A gamma-tocopherol-rich mixture of tocopherols inhibits colon inflammation and carcinogenesis in azoxymethane and dextran sulfate sodium-treated mice
    Jihyeung Ju
    Susan Lehman Cullman Laboratory for Cancer Research, Department of Chemical Biology, and Center for Cancer Prevention Research, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA
    Cancer Prev Res (Phila) 2:143-52. 2009
    ....

Research Grants2

  1. Fatty Liver Preventive Effects and High Dose Hepatotoxicity of Tea Polyphenols
    JOSHUA LAMBERT; Fiscal Year: 2009
    ..e. preexisting fatty liver disease) in which individuals may be sensitized to the hepatotoxic effects of EGCG. ..
  2. Fatty Liver Preventive Effects and High Dose Hepatotoxicity of Tea Polyphenols
    Joshua D Lambert; Fiscal Year: 2010
    ..e. preexisting fatty liver disease) in which individuals may be sensitized to the hepatotoxic effects of EGCG. ..