Anne M Karinch

Summary

Affiliation: Pennsylvania State University
Country: USA

Publications

  1. pmc Acute and chronic ethanol consumption differentially impact pathways limiting hepatic protein synthesis
    Anne M Karinch
    Department of Cellular and Molecular Physiology, MC H166, Penn State Univ College of Medicine, 500 Univ Drive, Hershey, PA 17033, USA
    Am J Physiol Endocrinol Metab 295:E3-9. 2008
  2. ncbi request reprint Stimulation of expression of the intestinal glutamine transporter ATB0 in tumor-bearing rats
    Haroon A Choudry
    Department of Surgery, The Milton S Hershey Medical Center, The Pennsylvania State University, College of Medicine, 500 University Drive, P O Box MC 850, Hershey, PA 17033, USA
    Ann Surg Oncol 13:1747-53. 2006
  3. ncbi request reprint Glucocorticoids have a role in renal cortical expression of the SNAT3 glutamine transporter during chronic metabolic acidosis
    Anne M Karinch
    Department of Surgery, Milton S Hershey Medical Center, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA
    Am J Physiol Renal Physiol 292:F448-55. 2007
  4. ncbi request reprint Epidermal growth factor activation of intestinal glutamine transport is mediated by mitogen-activated protein kinases
    Christopher L Wolfgang
    Department of Surgery, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, USA
    J Gastrointest Surg 7:149-56. 2003
  5. ncbi request reprint Insulin-like growth factor-2 activation of intestinal glutamine transport is mediated by mitogen-activated protein kinases
    Qinghe Meng
    Departments of Surgery, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, USA
    J Gastrointest Surg 8:40-7. 2004
  6. ncbi request reprint Metabolic acidosis stimulates intestinal glutamine absorption
    Mark J Epler
    Department of Surgery, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, USA
    J Gastrointest Surg 7:1045-52. 2003
  7. ncbi request reprint Activation of intestinal arginine transport by protein kinase C is mediated by mitogen-activated protein kinases
    Ming Pan
    Department of Surgery, Pennsylvania State University College of Medicine, MC 850, Hershey, PA 17033, USA
    J Gastrointest Surg 6:876-82. 2002
  8. ncbi request reprint Regulation of amino acid arginine transport by lipopolysaccharide and nitric oxide in intestinal epithelial IEC-6 cells
    Qinghe Meng
    Department of Surgery, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, USA
    J Gastrointest Surg 9:1276-85; discussion 1285. 2005
  9. ncbi request reprint Stimulation of intestinal glutamine absorption in chronic metabolic acidosis
    Ming Pan
    Department of Surgery, The Milton S Hershey Medical Center, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA
    Surgery 136:127-34. 2004
  10. ncbi request reprint Regulation of expression of the SN1 transporter during renal adaptation to chronic metabolic acidosis in rats
    Anne M Karinch
    Department of Surgery, Milton S Hershey Medical Center, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA
    Am J Physiol Renal Physiol 283:F1011-9. 2002

Collaborators

  • Ming Pan
  • THOMAS VARY
  • Qinghe Meng
  • Haroon A Choudry
  • Chengmao Lin
  • Wiley W Souba
  • Mark J Epler
  • Jingli Huang
  • Christopher L Wolfgang

Detail Information

Publications15

  1. pmc Acute and chronic ethanol consumption differentially impact pathways limiting hepatic protein synthesis
    Anne M Karinch
    Department of Cellular and Molecular Physiology, MC H166, Penn State Univ College of Medicine, 500 Univ Drive, Hershey, PA 17033, USA
    Am J Physiol Endocrinol Metab 295:E3-9. 2008
    ..Enhanced phosphorylation of eIF2alpha represents a unique response of liver to alcohol intoxication, because the ethanol-induced elevation of eIF2alpha(P) is not observed in skeletal muscle or heart...
  2. ncbi request reprint Stimulation of expression of the intestinal glutamine transporter ATB0 in tumor-bearing rats
    Haroon A Choudry
    Department of Surgery, The Milton S Hershey Medical Center, The Pennsylvania State University, College of Medicine, 500 University Drive, P O Box MC 850, Hershey, PA 17033, USA
    Ann Surg Oncol 13:1747-53. 2006
    ..The purpose of this in vivo study was to investigate intestinal glutamine transport and expression of glutamine transporter ATB(0) in methyl-cholanthrene (MCA)-sarcoma bearing rats...
  3. ncbi request reprint Glucocorticoids have a role in renal cortical expression of the SNAT3 glutamine transporter during chronic metabolic acidosis
    Anne M Karinch
    Department of Surgery, Milton S Hershey Medical Center, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA
    Am J Physiol Renal Physiol 292:F448-55. 2007
    ..These studies indicate that glucocorticoids regulate acid-base homeostasis during metabolic acidosis in part by regulating expression of the System N transporter SNAT3...
  4. ncbi request reprint Epidermal growth factor activation of intestinal glutamine transport is mediated by mitogen-activated protein kinases
    Christopher L Wolfgang
    Department of Surgery, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, USA
    J Gastrointest Surg 7:149-56. 2003
    ..EGF activates glutamine transport via alterations in transporter mRNA levels and the number of functional copies of transporter units...
  5. ncbi request reprint Insulin-like growth factor-2 activation of intestinal glutamine transport is mediated by mitogen-activated protein kinases
    Qinghe Meng
    Departments of Surgery, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, USA
    J Gastrointest Surg 8:40-7. 2004
    ..Activation of mitogen-activated protein kinases and protein kinase C cascades are involved in the regulation. This increase in glutamine uptake may occur to support intestinal cell growth and proliferation...
  6. ncbi request reprint Metabolic acidosis stimulates intestinal glutamine absorption
    Mark J Epler
    Department of Surgery, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, USA
    J Gastrointest Surg 7:1045-52. 2003
    ..Mitogen-activated protein kinases are key intracellular regulators involved in this signal transduction cascade. An increased availability of glutamine to cells subjected to redox stress may help in maintaining cellular integrity...
  7. ncbi request reprint Activation of intestinal arginine transport by protein kinase C is mediated by mitogen-activated protein kinases
    Ming Pan
    Department of Surgery, Pennsylvania State University College of Medicine, MC 850, Hershey, PA 17033, USA
    J Gastrointest Surg 6:876-82. 2002
    ..Protein kinase C and MAP kinases MEK1/2 and p44/42 are key intracellular regulators involved in this signal transduction cascade...
  8. ncbi request reprint Regulation of amino acid arginine transport by lipopolysaccharide and nitric oxide in intestinal epithelial IEC-6 cells
    Qinghe Meng
    Department of Surgery, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, USA
    J Gastrointest Surg 9:1276-85; discussion 1285. 2005
    ..The LPS-stimulated arginine transport activity is regulated by the availability of nitric oxide...
  9. ncbi request reprint Stimulation of intestinal glutamine absorption in chronic metabolic acidosis
    Ming Pan
    Department of Surgery, The Milton S Hershey Medical Center, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA
    Surgery 136:127-34. 2004
    ..The purpose of this in vivo study was to investigate the regulation of intestinal glutamine absorption during chronic metabolic acidosis...
  10. ncbi request reprint Regulation of expression of the SN1 transporter during renal adaptation to chronic metabolic acidosis in rats
    Anne M Karinch
    Department of Surgery, Milton S Hershey Medical Center, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA
    Am J Physiol Renal Physiol 283:F1011-9. 2002
    ..These data provide evidence that regulation of expression of the SN1 amino acid transporter is part of the renal homeostatic response to acid-base imbalance...
  11. ncbi request reprint Branched-chain amino acid-enriched nutritional support in surgical and cancer patients
    Haroon A Choudry
    Department of Surgery, The Pennsylvania State University, College of Medicine, The Milton S Hershey Medical Center, Hershey, PA, USA
    J Nutr 136:314S-8S. 2006
    ..In summary, the role of BCAAs in the nutritional support of stressed surgical and cancer patients remains to be clearly defined, despite their potential beneficial biological properties...
  12. ncbi request reprint Specific reversible stimulation of system y(+) L-arginine transport activity in human intestinal cells
    Ming Pan
    Department of Surgery, Penn State College of Medicine, Milton S Hershey Medical Center, Hershey, PA 17033, USA
    J Gastrointest Surg 6:379-86. 2002
    ..These findings identify a mechanism by which luminal nutrients regulate arginine uptake by the gut...
  13. ncbi request reprint Protein kinase C activation of intestinal glutamine transport is mediated by mitogen-activated protein kinases
    Ming Pan
    Department of Surgery, Penn State College of Medicine, Hershey, PA 17033, USA
    J Surg Res 106:137-44. 2002
    ..Our hypothesis was that the activation of intestinal glutamine transport involves protein kinase C (PKC) and is mediated by mitogen-activated protein kinases (MAPKs)...
  14. ncbi request reprint Epidermal growth factor regulation of system L alanine transport in undifferentiated and differentiated intestinal Caco-2 cells
    Ming Pan
    Department of Surgery, Pennsylvania State College of Medicine, Milton S Hershey Medical Center, Hershey, PA 17033, USA
    J Gastrointest Surg 6:410-7. 2002
    ..Both cell differentiation and EGF regulation of system L activity occur via alteration of functional copies of the system L transporter...
  15. ncbi request reprint Posttranslational alanine trans-stimulation of zwitterionic amino acid transport systems in human intestinal Caco-2 cells
    Ming Pan
    Department of Surgery, Pennsylvania State University, Hershey, Pennsylvania 17033, USA
    J Surg Res 104:63-9. 2002
    ..This study examined the effects of acute amino acid substrate exposure on the rapid modulation of apical membrane alanine transport in cultured human intestinal cells...