Anita K Hopper

Summary

Affiliation: Pennsylvania State University
Country: USA

Publications

  1. ncbi request reprint Nucleocytoplasmic transport: Inside out regulation
    A K Hopper
    Department of Biochemistry and Molecular Biology, H171, Pennsylvania State University College of Medicine, 500 University Drive, Hershey, Pennsylvania 17033, USA
    Curr Biol 9:R803-6. 1999
  2. ncbi request reprint Cellular dynamics of small RNAs
    Anita K Hopper
    Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA 17033, USA
    Crit Rev Biochem Mol Biol 41:3-19. 2006
  3. ncbi request reprint tRNA transfers to the limelight
    Anita K Hopper
    Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, USA
    Genes Dev 17:162-80. 2003
  4. pmc Retrograde movement of tRNAs from the cytoplasm to the nucleus in Saccharomyces cerevisiae
    Hussam H Shaheen
    Department of Biochemistry and Molecular Biology, C5757, H171, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA
    Proc Natl Acad Sci U S A 102:11290-5. 2005
  5. pmc Rapid and reversible nuclear accumulation of cytoplasmic tRNA in response to nutrient availability
    Michael L Whitney
    Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA
    Mol Biol Cell 18:2678-86. 2007
  6. pmc Genome-wide screen for inner nuclear membrane protein targeting in Saccharomyces cerevisiae: roles for N-acetylation and an integral membrane protein
    Athulaprabha Murthi
    Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, USA
    Genetics 170:1553-60. 2005
  7. pmc A Los1p-independent pathway for nuclear export of intronless tRNAs in Saccharomycescerevisiae
    Wenqin Feng
    Department of Biochemistry and Molecular Biology, H171, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA
    Proc Natl Acad Sci U S A 99:5412-7. 2002
  8. pmc Importin-beta family members mediate alpharetrovirus gag nuclear entry via interactions with matrix and nucleocapsid
    Kristin L Butterfield-Gerson
    Division of Infectious Diseases HO36, Penn State College of Medicine, 500 University Drive, Hershey, PA 17033, USA
    J Virol 80:1798-806. 2006
  9. ncbi request reprint tRNA traffic meets a cell-cycle checkpoint
    Ted Weinert
    Department of Molecular and Cellular Biology, University of Arizona, Life Sciences South 546, P O Box 210106, Tucson, AZ 85721 0106, USA
    Cell 131:838-40. 2007
  10. pmc Retrograde nuclear accumulation of cytoplasmic tRNA in rat hepatoma cells in response to amino acid deprivation
    Hussam H Shaheen
    Department of Molecular Genetics, Ohio State University, 484 West 12th Avenue, Room Riffe 800, Columbus, OH 43210, USA
    Proc Natl Acad Sci U S A 104:8845-50. 2007

Collaborators

  • S R Kimball
  • L S Jefferson
  • Eric Phizicky
  • Ted Weinert
  • Hussam H Shaheen
  • Rebecca L Hurto
  • Athulaprabha Murthi
  • Michael L Whitney
  • David R Engelke
  • Kristin L Butterfield-Gerson
  • Marta Kwapisz
  • Weifeng Gu
  • Wenqin Feng
  • Joanna Kaminska
  • Charles Boone
  • Amy Hin Yan Tong
  • Rick L Horetsky
  • Eileen P Ryan
  • Leslie J Parent
  • Lisa Z Scheifele
  • Piotr Cholbinski
  • Teresa Zoladek
  • Jean Pierre Rousset
  • Elizabeth J Grayhack
  • Teresa ZoƂadek
  • Beata Gajewska

Detail Information

Publications16

  1. ncbi request reprint Nucleocytoplasmic transport: Inside out regulation
    A K Hopper
    Department of Biochemistry and Molecular Biology, H171, Pennsylvania State University College of Medicine, 500 University Drive, Hershey, Pennsylvania 17033, USA
    Curr Biol 9:R803-6. 1999
    ..Recent findings in budding yeast indicate that the nuclear transport receptor Msn5p mediates the nuclear export of several transcription regulators after their phosphorylation in the nucleus...
  2. ncbi request reprint Cellular dynamics of small RNAs
    Anita K Hopper
    Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA 17033, USA
    Crit Rev Biochem Mol Biol 41:3-19. 2006
    ..This report discusses data that support or argue against nucleus/cytoplasm bidirectional movement for each category of small RNA and the possible roles that such movement may serve...
  3. ncbi request reprint tRNA transfers to the limelight
    Anita K Hopper
    Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, USA
    Genes Dev 17:162-80. 2003
  4. pmc Retrograde movement of tRNAs from the cytoplasm to the nucleus in Saccharomyces cerevisiae
    Hussam H Shaheen
    Department of Biochemistry and Molecular Biology, C5757, H171, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA
    Proc Natl Acad Sci U S A 102:11290-5. 2005
    ..Nuclear accumulation of cytoplasmic tRNA requires Ran and the Mtr10/Kap111 member of the importin-beta family. Retrograde tRNA nuclear import may provide a novel mechanism to regulate gene expression in eukaryotes...
  5. pmc Rapid and reversible nuclear accumulation of cytoplasmic tRNA in response to nutrient availability
    Michael L Whitney
    Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA
    Mol Biol Cell 18:2678-86. 2007
    ..These findings suggest tRNA nucleocytoplasmic distribution may play a role in gene expression in response to nutritional stress...
  6. pmc Genome-wide screen for inner nuclear membrane protein targeting in Saccharomyces cerevisiae: roles for N-acetylation and an integral membrane protein
    Athulaprabha Murthi
    Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, USA
    Genetics 170:1553-60. 2005
    ..Our methodology can be extrapolated to obtain genome-wide perspectives of mechanisms necessary to achieve appropriate subcellular and/or suborganellar location for any resident protein...
  7. pmc A Los1p-independent pathway for nuclear export of intronless tRNAs in Saccharomycescerevisiae
    Wenqin Feng
    Department of Biochemistry and Molecular Biology, H171, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA
    Proc Natl Acad Sci U S A 99:5412-7. 2002
    ..In contrast, we show that overexpressed Cca1p corrects the nuclear export, but not the pre-tRNA-splicing defects of los1Kan(r) cells, thereby uncoupling pre-tRNA splicing and tRNA nuclear export...
  8. pmc Importin-beta family members mediate alpharetrovirus gag nuclear entry via interactions with matrix and nucleocapsid
    Kristin L Butterfield-Gerson
    Division of Infectious Diseases HO36, Penn State College of Medicine, 500 University Drive, Hershey, PA 17033, USA
    J Virol 80:1798-806. 2006
    ..Thus, the nucleocytoplasmic dynamics of RSV Gag depend upon the counterbalance of Crm1p-mediated export with two independent NLSs, each interacting with distinct nuclear import factors...
  9. ncbi request reprint tRNA traffic meets a cell-cycle checkpoint
    Ted Weinert
    Department of Molecular and Cellular Biology, University of Arizona, Life Sciences South 546, P O Box 210106, Tucson, AZ 85721 0106, USA
    Cell 131:838-40. 2007
    ..2007) reported in this issue suggest that tRNA trafficking and the transcription factor Gcn4 are key intermediates in the process by which yeast cells detect DNA damage and delay cell-cycle progression at the G1 to S phase transition...
  10. pmc Retrograde nuclear accumulation of cytoplasmic tRNA in rat hepatoma cells in response to amino acid deprivation
    Hussam H Shaheen
    Department of Molecular Genetics, Ohio State University, 484 West 12th Avenue, Room Riffe 800, Columbus, OH 43210, USA
    Proc Natl Acad Sci U S A 104:8845-50. 2007
    ....
  11. pmc Inorganic phosphate deprivation causes tRNA nuclear accumulation via retrograde transport in Saccharomyces cerevisiae
    Rebecca L Hurto
    Department of Molecular Genetics, Ohio State University, Columbus, Ohio 43210, USA
    Genetics 176:841-52. 2007
    ....
  12. ncbi request reprint Modified view of tRNA: stability amid sequence diversity
    David R Engelke
    Department of Biological Chemistry, The University of Michigan, 1150 West Medical Center Drive, 3200 MSRB III, Ann Arbor, Michigan 48109, USA
    Mol Cell 21:144-5. 2006
    ..Alexandrov et al. (2006) show that tRNA modifications can play an important role in tRNA stability, as without particular modifications, tRNA half-life can be reduced from hours to minutes by a new turnover pathway...
  13. pmc Rsp5 ubiquitin ligase modulates translation accuracy in yeast Saccharomyces cerevisiae
    Marta Kwapisz
    Department of Genetics, Institute of Biochemistry and Biophysics, PAS, Warsaw, Poland
    RNA 11:1710-8. 2005
    ..This defect, also reversed by overproduction of the elongation factor eEF1A, may be the primary reason for altered translational decoding accuracy...
  14. pmc Depletion of Saccharomyces cerevisiae tRNA(His) guanylyltransferase Thg1p leads to uncharged tRNAHis with additional m(5)C
    Weifeng Gu
    Department of Biochemistry and Biophysics, University of Rochester School of Medicine, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Mol Cell Biol 25:8191-201. 2005
    ..We developed a new method to map m(5)C residues in RNA and localized the additional m(5)C to positions 48 and 50. This is the first documented example of the accumulation of additional modifications in a eukaryotic tRNA species...
  15. doi request reprint A decade of surprises for tRNA nuclear-cytoplasmic dynamics
    Anita K Hopper
    Department of Molecular Genetics, Ohio State University, 484 West 12th Avenue, Room Riffe 800, Columbus, OH 43210, USA
    Trends Cell Biol 18:98-104. 2008
    ..Moreover, the subcellular distribution of tRNA seems to serve unanticipated functions in diverse processes, including response to nutrient availability, DNA repair and HIV replication...
  16. pmc Rsp5p, a new link between the actin cytoskeleton and endocytosis in the yeast Saccharomyces cerevisiae
    Joanna Kaminska
    Department of Genetics, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland
    Mol Cell Biol 22:6946-8. 2002
    ..iv) rsp5-w1 mutants are resistant to latrunculin A, a drug that sequesters actin monomers and depolymerizes actin filaments, consistent with the fact that Rsp5p is involved in actin cytoskeleton dynamics...